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Edexcel A‑Level Biology B questions by topic

Every question from every Edexcel A-Level Biology B paper, 2016–2025, part by part. Filter by topic, paper or year, open the mark scheme under any question, and download a set as a PDF.

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Year 1 · AS

Year 2 · A‑Level only

Calculations

1,826 questions

  1. Q1(a)

    June 2025 · Paper 1

    1 mark
    The whole paper ↗
    June 2025 Paper 1, question 1(a): What happens during active transport? (1) A ATP is hydrolysed releasing energy B ATP is hydrolysed using energy C ATP is phosphorylated releasing energy D ATP i

  2. Q1(b)

    June 2025 · Paper 1

    1 mark
    The whole paper ↗
    June 2025 Paper 1, question 1(b): Which substance is transported against a concentration gradient by active transport? (1) A hydrophilic molecule B large hydrophobic molecule C small hydrophobic

  3. Q1(c)

    June 2025 · Paper 1

    2 marks
    The whole paper ↗
    June 2025 Paper 1, question 1(c): The graph shows the change in concentration of molecule A and molecule B, as they are transported into the cytoplasm of a cell. molecule A Concentration of mole

  4. Q2(a)

    June 2025 · Paper 1

    1 mark
    The whole paper ↗
    June 2025 Paper 1, question 2(a): Which is molecule X? (1) A glycerate 3-phosphate B glycogen C lactate D pyruvate

  5. Q2(b)

    June 2025 · Paper 1

    1 mark
    The whole paper ↗
    June 2025 Paper 1, question 2(b): Which row of the table shows the locations of glycolysis, the link reaction and the Krebs cycle in eukaryotic cells? (1) Glycolysis Link reaction Krebs cycle A

  6. Q2(c)(i)

    June 2025 · Paper 1

    2 marks
    The whole paper ↗
    June 2025 Paper 1, question 2(c)(i): The oxidation of one glucose molecule yields 2 870 224 Joules. The free energy stored in one ATP molecule is 30 566 Joules. Calculate the efficiency of energy t

  7. Q2(c)(ii)

    June 2025 · Paper 1

    1 mark
    The whole paper ↗
    June 2025 Paper 1, question 2(c)(ii): State why this process is not 100 % efficient. (1)

  8. Q3(a)

    June 2025 · Paper 1

    1 mark
    The whole paper ↗
    June 2025 Paper 1, question 3(a): State why specifically-selected cell types have to be grown in Step 1. (1)

  9. Q3(b)

    June 2025 · Paper 1

    2 marks
    The whole paper ↗
    June 2025 Paper 1, question 3(b): Explain why the flask has to be incubated at an appropriate temperature for a few days in Step 3. (2)

  10. Q3(c)

    June 2025 · Paper 1

    3 marks
    The whole paper ↗
    June 2025 Paper 1, question 3(c): Explain why the viruses and not the cells will be present in the filtrate in Step 5. (3)

  11. Q4(a)(i)

    June 2025 · Paper 1

    1 mark
    The whole paper ↗
    June 2025 Paper 1, question 4(a)(i): Which row in the table describes parts R and S of the phospholipid? (1) Part R Part S A hydrophilic fatty acid hydrophobic phosphate B hydrophilic phosphate hyd

  12. Q4(a)(ii)

    June 2025 · Paper 1

    2 marks
    The whole paper ↗
    June 2025 Paper 1, question 4(a)(ii): Draw part of a cell surface membrane that has twelve phospholipids, one channel protein and one cholesterol molecule. Use the components shown in the diagram. (

  13. Q4(a)(iii)

    June 2025 · Paper 1

    2 marks
    The whole paper ↗
    June 2025 Paper 1, question 4(a)(iii): Describe the role of channel proteins in cell transport. (2)

  14. Q4(b)(i)

    June 2025 · Paper 1

    2 marks
    The whole paper ↗
    June 2025 Paper 1, question 4(b)(i): Analyse the data to give two conclusions that can be made from this graph. (2)

  15. Q4(b)(ii)

    June 2025 · Paper 1

    2 marks
    The whole paper ↗
    June 2025 Paper 1, question 4(b)(ii): Explain the effect of temperature on membrane permeability at point P. (2)

  16. Q5(a)

    June 2025 · Paper 1

    1 mark
    The whole paper ↗
    June 2025 Paper 1, question 5(a): Which of the following describes the chromosome mutation that causes TS? (1) A non-disjunction leading to monosomy B non-disjunction leading to polysomy C trans

  17. Q5(b)

    June 2025 · Paper 1

    2 marks
    The whole paper ↗
    June 2025 Paper 1, question 5(b): There were 613 936 babies born in the UK in 2020. The ratio of baby boys to baby girls is 1.05 : 1. The incidence of TS is between 1 in 2 000 and 1 in 2 500 in

  18. Q5(c)(i)

    June 2025 · Paper 1

    3 marks
    The whole paper ↗
    June 2025 Paper 1, question 5(c)(i): Girls who had recently been vaccinated were excluded from this study. Explain why these girls were excluded. (3)

  19. Q5(c)(ii)

    June 2025 · Paper 1

    2 marks
    The whole paper ↗
    June 2025 Paper 1, question 5(c)(ii): The table shows some of the physical features of the two groups of girls. Mean value ± SD for each group of girls Physical features With TS Without TS Age / yea

  20. Q5(c)(iii)

    June 2025 · Paper 1

    2 marks
    The whole paper ↗
    June 2025 Paper 1, question 5(c)(iii): The table shows the levels of four immunological markers in the blood of each group of girls. Mean value ± SD for each group of girls Immunological marker With

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