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Oxidative phosphorylation: Edexcel A‑Level Biology B questions

Every Edexcel A-Level Biology B exam question on 5.4 Oxidative phosphorylation, 2016–2025, with its mark scheme and examiner’s report.

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1,826 questions

  1. Q7(a)(ii)

    June 2024 · Paper 1

    3 marks5.4 Oxidative phosphorylation
    The whole paper ↗
    June 2024 Paper 1, question 7(a)(ii): In the mitochondria, ATP is synthesised on the inner mitochondrial membrane. Leakage of protons (H+) across the inner mitochondrial membrane reduces ATP synthes

  2. Q9(a)(i)

    June 2023 · Paper 1

    1 mark5.4 Oxidative phosphorylation
    The whole paper ↗
    June 2023 Paper 1, question 9(a)(i): Where is the electron transport chain located in mitochondria? (1) A inner membrane B intermembrane space C matrix D outer membrane

  3. Q9(a)(ii)

    June 2023 · Paper 1

    3 marks5.4 Oxidative phosphorylation
    The whole paper ↗
    June 2023 Paper 1, question 9(a)(ii): Explain why inactivating cytochrome c oxidase could be fatal. (3)

  4. Q10(d)

    June 2023 · Paper 3

    3 marks5.4 Oxidative phosphorylation
    The whole paper ↗
    June 2023 Paper 3, question 10(d): Describe the role of oxygen in the formation of ATP during aerobic respiration. (3)

  5. Q5(b)(i)

    November 2021 · Paper 1

    1 mark5.4 Oxidative phosphorylation
    The whole paper ↗
    November 2021 Paper 1, question 5(b)(i): Give one difference in the membranes of this mitochondrion compared with the membranes of a mitochondrion from an untreated cancer cell. (1)

  6. Q5(b)(ii)

    November 2021 · Paper 1

    2 marks5.4 Oxidative phosphorylation
    The whole paper ↗
    November 2021 Paper 1, question 5(b)(ii): Some cancer cells depend on oxidative phosphorylation for ATP production. Explain why the antibiotics that inhibit the production of ribosomes prevent oxidative

  7. Q7(c)

    October 2020 · Paper 1

    2 marks5.4 Oxidative phosphorylation
    The whole paper ↗
    October 2020 Paper 1, question 7(c): The electron transport chain uses hydrogen ions to generate ATP. Explain why the respiration of lipids generates more ATP than the respiration of carbohydrates.

  8. Q8(a)

    October 2020 · Paper 3

    1 mark5.4 Oxidative phosphorylation
    The whole paper ↗
    October 2020 Paper 3, question 8(a): State the location of the electron transport chain in a mitochondrion. (1)

  9. Q8(b)(i)

    October 2020 · Paper 3

    5 marks5.4 Oxidative phosphorylation
    The whole paper ↗
    October 2020 Paper 3, question 8(b)(i): Explain why hydrogen cyanide gas can kill an animal. (5)

  10. Q8(b)(ii)

    October 2020 · Paper 3

    3 marks5.4 Oxidative phosphorylation
    The whole paper ↗
    October 2020 Paper 3, question 8(b)(ii): A dose of 1.0 mg of hydrogen cyanide per kilogram of body mass is fatal. An animal with a body mass of 10 kg inhaled air containing 0.24 mg dm−3 of hydrogen cya

  11. Q8(c)

    October 2020 · Paper 3

    2 marks5.4 Oxidative phosphorylation
    The whole paper ↗
    October 2020 Paper 3, question 8(c): The effect of cyanide on oxygen uptake by mitochondria was investigated using the following method: ● suspend mitochondria in a flask containing a buffer soluti

  12. Q4(b)

    June 2019 · Paper 1

    6 marks5.4 Oxidative phosphorylation
    The whole paper ↗
    June 2019 Paper 1, question 4(b): The table shows the protein : lipid ratio of the inner and outer membrane of a mitochondrion. Membrane of Protein : lipid mitochondrion ratio inner 3:2 outer 1:

  13. Q8(a)

    June 2019 · Paper 3

    2 marks5.4 Oxidative phosphorylation
    The whole paper ↗
    June 2019 Paper 3, question 8(a): Describe what happens to oxygen at the end of the electron transport chain. (2)

  14. Q7(b)(ii)

    June 2017 · Paper 1

    3 marks1.4 DNA and protein synthesis5.4 Oxidative phosphorylation
    The whole paper ↗
    June 2017 Paper 1, question 7(b)(ii): Explain how this mutation could affect oxidative phosphorylation. (3)
All 14 questions on Oxidative phosphorylation, as a list
  1. June 2024, Paper 1, Q7(a)(ii) (3 marks): In the mitochondria, ATP is synthesised on the inner mitochondrial membrane. Leakage of protons (H+) across the inner mitochondrial membrane reduces ATP synthes
  2. June 2023, Paper 1, Q9(a)(i) (1 mark): Where is the electron transport chain located in mitochondria? (1) A inner membrane B intermembrane space C matrix D outer membrane
  3. June 2023, Paper 1, Q9(a)(ii) (3 marks): Explain why inactivating cytochrome c oxidase could be fatal. (3)
  4. June 2023, Paper 3, Q10(d) (3 marks): Describe the role of oxygen in the formation of ATP during aerobic respiration. (3)
  5. November 2021, Paper 1, Q5(b)(i) (1 mark): Give one difference in the membranes of this mitochondrion compared with the membranes of a mitochondrion from an untreated cancer cell. (1)
  6. November 2021, Paper 1, Q5(b)(ii) (2 marks): Some cancer cells depend on oxidative phosphorylation for ATP production. Explain why the antibiotics that inhibit the production of ribosomes prevent oxidative
  7. October 2020, Paper 1, Q7(c) (2 marks): The electron transport chain uses hydrogen ions to generate ATP. Explain why the respiration of lipids generates more ATP than the respiration of carbohydrates.
  8. October 2020, Paper 3, Q8(a) (1 mark): State the location of the electron transport chain in a mitochondrion. (1)
  9. October 2020, Paper 3, Q8(b)(i) (5 marks): Explain why hydrogen cyanide gas can kill an animal. (5)
  10. October 2020, Paper 3, Q8(b)(ii) (3 marks): A dose of 1.0 mg of hydrogen cyanide per kilogram of body mass is fatal. An animal with a body mass of 10 kg inhaled air containing 0.24 mg dm−3 of hydrogen cya
  11. October 2020, Paper 3, Q8(c) (2 marks): The effect of cyanide on oxygen uptake by mitochondria was investigated using the following method: ● suspend mitochondria in a flask containing a buffer soluti
  12. June 2019, Paper 1, Q4(b) (6 marks): The table shows the protein : lipid ratio of the inner and outer membrane of a mitochondrion. Membrane of Protein : lipid mitochondrion ratio inner 3:2 outer 1:
  13. June 2019, Paper 3, Q8(a) (2 marks): Describe what happens to oxygen at the end of the electron transport chain. (2)
  14. June 2017, Paper 1, Q7(b)(ii) (3 marks): Explain how this mutation could affect oxidative phosphorylation. (3)

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