Skip to content
Try on iPad

Factors affecting gene expression: Edexcel A‑Level Biology B questions

Every Edexcel A-Level Biology B exam question on 7.2 Factors affecting gene expression, 2016–2025, with its mark scheme and examiner’s report.

Find questions1,826
Calculations

1,826 questions

  1. Q8(c)(i)

    June 2025 · Paper 1

    3 marks7.2 Factors affecting gene expression
    The whole paper ↗
    June 2025 Paper 1, question 8(c)(i): Determine the effect of growing plants in low levels of nitrogen gas and in high levels of nitrogen gas on the changes in gene expression. (3)

  2. Q8(c)(ii)

    June 2025 · Paper 1

    2 marks7.2 Factors affecting gene expression
    The whole paper ↗
    June 2025 Paper 1, question 8(c)(ii): Describe how gene expression can be changed. (2)

  3. Q8(c)

    June 2024 · Paper 1

    3 marks7.2 Factors affecting gene expression
    The whole paper ↗
    June 2024 Paper 1, question 8(c): In some infertile males, the gene coding for protein G is methylated. Explain why DNA‑methylation of this gene could result in infertility. (3)

  4. Q9(b)(ii)

    June 2024 · Paper 1

    6 marks7.2 Factors affecting gene expression1.4 DNA and protein synthesis
    The whole paper ↗
    June 2024 Paper 1, question 9(b)(ii): The product of the BCL11A gene regulates the switch from the synthesis of fetal to adult globin subunits. Analyse all the information in this question to discus

  5. Q9(b)(i)

    June 2023 · Paper 1

    1 mark7.2 Factors affecting gene expression
    The whole paper ↗
    June 2023 Paper 1, question 9(b)(i): State the meaning of the term epigenetic modification. (1)

  6. Q9(b)(ii)

    June 2023 · Paper 1

    1 mark7.2 Factors affecting gene expression
    The whole paper ↗
    June 2023 Paper 1, question 9(b)(ii): Which of the following is another type of epigenetic modification? (1) A deletion mutation B histone modification C translation D translocation

  7. Q9(c)

    June 2023 · Paper 1

    6 marks7.2 Factors affecting gene expression
    The whole paper ↗
    June 2023 Paper 1, question 9(c): The effect of hydrogen sulfide (H2S) on DNA methylation in these fish was investigated. The flow diagram shows part of the method used in this investigation. Al

  8. Q8(b)(i)

    June 2022 · Paper 1

    2 marks7.2 Factors affecting gene expression
    The whole paper ↗
    June 2022 Paper 1, question 8(b)(i): Explain how HIF could result in an increase in the rate of glycolysis. (2)

  9. Q8(b)(iii)

    June 2022 · Paper 1

    2 marks7.2 Factors affecting gene expression
    The whole paper ↗
    June 2022 Paper 1, question 8(b)(iii): The graph shows the changes in levels of two HIFs, HIF‑1 and HIF‑2, before and during hypoxia. Before hypoxia During hypoxia HIF‑2 Level of HIF HIF‑1 Time Compa

  10. Q8(b)(iv)

    June 2022 · Paper 1

    2 marks7.2 Factors affecting gene expression
    The whole paper ↗
    June 2022 Paper 1, question 8(b)(iv): Explain the changes in levels of HIF‑1 and HIF‑2 during hypoxia. (2)

  11. Q5(a)(i)

    June 2019 · Paper 1

    1 mark7.2 Factors affecting gene expression
    The whole paper ↗
    June 2019 Paper 1, question 5(a)(i): State the meaning of the term DNA methylation. (1)

  12. Q2(b)

    June 2018 · Paper 1

    3 marks7.2 Factors affecting gene expression
    The whole paper ↗
    June 2018 Paper 1, question 2(b): Describe how this precursor molecule is modified to produce a tRNA molecule specific for the amino acid proline. (3)

  13. Q9(b)

    June 2017 · Paper 1

    3 marks7.2 Factors affecting gene expression
    The whole paper ↗
    June 2017 Paper 1, question 9(b): Epigenetic modification is involved in the formation of the antibody-producing cells. Describe epigenetic modification. (3)
All 13 questions on Factors affecting gene expression, as a list
  1. June 2025, Paper 1, Q8(c)(i) (3 marks): Determine the effect of growing plants in low levels of nitrogen gas and in high levels of nitrogen gas on the changes in gene expression. (3)
  2. June 2025, Paper 1, Q8(c)(ii) (2 marks): Describe how gene expression can be changed. (2)
  3. June 2024, Paper 1, Q8(c) (3 marks): In some infertile males, the gene coding for protein G is methylated. Explain why DNA‑methylation of this gene could result in infertility. (3)
  4. June 2024, Paper 1, Q9(b)(ii) (6 marks): The product of the BCL11A gene regulates the switch from the synthesis of fetal to adult globin subunits. Analyse all the information in this question to discus
  5. June 2023, Paper 1, Q9(b)(i) (1 mark): State the meaning of the term epigenetic modification. (1)
  6. June 2023, Paper 1, Q9(b)(ii) (1 mark): Which of the following is another type of epigenetic modification? (1) A deletion mutation B histone modification C translation D translocation
  7. June 2023, Paper 1, Q9(c) (6 marks): The effect of hydrogen sulfide (H2S) on DNA methylation in these fish was investigated. The flow diagram shows part of the method used in this investigation. Al
  8. June 2022, Paper 1, Q8(b)(i) (2 marks): Explain how HIF could result in an increase in the rate of glycolysis. (2)
  9. June 2022, Paper 1, Q8(b)(iii) (2 marks): The graph shows the changes in levels of two HIFs, HIF‑1 and HIF‑2, before and during hypoxia. Before hypoxia During hypoxia HIF‑2 Level of HIF HIF‑1 Time Compa
  10. June 2022, Paper 1, Q8(b)(iv) (2 marks): Explain the changes in levels of HIF‑1 and HIF‑2 during hypoxia. (2)
  11. June 2019, Paper 1, Q5(a)(i) (1 mark): State the meaning of the term DNA methylation. (1)
  12. June 2018, Paper 1, Q2(b) (3 marks): Describe how this precursor molecule is modified to produce a tRNA molecule specific for the amino acid proline. (3)
  13. June 2017, Paper 1, Q9(b) (3 marks): Epigenetic modification is involved in the formation of the antibody-producing cells. Describe epigenetic modification. (3)

Questions, mark schemes and examiner’s reports are © Pearson Edexcel, from their published past papers. Plumi isn’t affiliated with any exam board. Want whole papers? Every Edexcel A-Level Biology B paper.

Rather write your answers by hand on iPad? Plumi marks them against the same mark schemes.