Skip to content

Osmoregulation and temperature regulation: Edexcel A‑Level Biology B questions

Every Edexcel A-Level Biology B exam question on 9.9 Osmoregulation and temperature regulation, 2016–2025, with its mark scheme and examiner’s report.

Find questions1,826
Calculations

1,826 questions

  1. Q7(c)(i)

    June 2025 · Paper 2

    The whole paper ↗
    June 2025 Paper 2, question 7(c)(i): Calculate the maximum rate that the inulin is removed from the blood. Give your answer to two decimal places with appropriate units. (2) Answer
  2. Q7(c)(ii)

    June 2025 · Paper 2

    The whole paper ↗
    June 2025 Paper 2, question 7(c)(ii): Explain how inulin passes from the blood plasma into the proximal convoluted tubule of a nephron. (2)
  3. Q7(c)(iii)

    June 2025 · Paper 2

    The whole paper ↗
    June 2025 Paper 2, question 7(c)(iii): Explain why all the inulin is released into the urine. (2)
  4. Q7(b)(i)

    June 2024 · Paper 2

    The whole paper ↗
    June 2024 Paper 2, question 7(b)(i): Explain the changes in core body temperature and skin temperature during exercise, using the information in the graphs. (4)
  5. Q7(b)(ii)

    June 2024 · Paper 2

    The whole paper ↗
    June 2024 Paper 2, question 7(b)(ii): Mammals are endotherms. Give one method that ectotherms, such as reptiles, can use to thermoregulate. (1)
  6. Q7(c)

    June 2024 · Paper 2

    The whole paper ↗
    June 2024 Paper 2, question 7(c): The hypothalamus plays a role in osmoregulation. Describe how stimulation of the hypothalamus leads to the production of concentrated urine. (3)
  7. Q2(a)(i)

    June 2024 · Paper 3

    The whole paper ↗
    June 2024 Paper 3, question 2(a)(i): Explain how urea enters the nephron. (2)
  8. Q2(a)(ii)

    June 2024 · Paper 3

    The whole paper ↗
    June 2024 Paper 3, question 2(a)(ii): In the region labelled A, sodium ions are actively pumped out of the nephron into the surrounding fluid. Explain how this movement of ions results in the format
  9. Q2(b)(i)

    June 2024 · Paper 3

    The whole paper ↗
    June 2024 Paper 3, question 2(b)(i): Determine the ratio of urine concentration for these three mammals. (1) Answer
  10. Q2(b)(ii)

    June 2024 · Paper 3

    The whole paper ↗
    June 2024 Paper 3, question 2(b)(ii): Kangaroo rats live in a desert habitat. Explain one adaptation in the structure of a kangaroo rat kidney that enables it to produce very concentrated urine. (2)
  11. Q2(b)(iii)

    June 2024 · Paper 3

    The whole paper ↗
    June 2024 Paper 3, question 2(b)(iii): Kangaroo rats are endotherms. Give one behavioural adaptation that you would expect to see in kangaroo rats that helps them to conserve water in a hot desert. (
  12. Q6(a)

    June 2022 · Paper 2

    The whole paper ↗
    June 2022 Paper 2, question 6(a): Which labelled parts of this nephron would normally contain glucose? (1) A W only B W and X C W, X, and Y D W, X, Y, and Z
  13. Q6(b)(ii)

    June 2022 · Paper 2

    The whole paper ↗
    June 2022 Paper 2, question 6(b)(ii): Furosemides are drugs that are used to reduce oedema. They are diuretics that increase urine production. Furosemides reduce the active transport of sodium ions
  14. Q6(b)(ii)

    November 2021 · Paper 2

    The whole paper ↗
    November 2021 Paper 2, question 6(b)(ii): Capsaicin affects sweat production. It has been suggested that capsaicin could be used to lower the temperature of people with fevers. The effect of three diffe
  15. Q7(c)(ii)

    November 2021 · Paper 3

    The whole paper ↗
    November 2021 Paper 3, question 7(c)(ii): Explain how, on a very hot day, the brain ensures that the water potential of the blood remains constant. (4)
  16. Q3(a)

    October 2020 · Paper 2

    The whole paper ↗
    October 2020 Paper 2, question 3(a): The diagram shows a cell from the proximal convoluted tubule of the nephron. Explain how the features shown in the diagram enable this cell to carry out its fun
  17. Q3(b)(ii)

    October 2020 · Paper 2

    The whole paper ↗
    October 2020 Paper 2, question 3(b)(ii): The collecting duct is also part of the nephron. Which of the following are the effects of increased release of antidiuretic hormone (ADH)? (1) A decreased perm
  18. October 2020 Paper 3, question 7(c): Wood mice are small mammals. They cannot maintain their body temperature and will die if left in the trap for a long period of time. Explain why wood mice canno
  19. Q2(a)(i)

    June 2019 · Paper 3

    The whole paper ↗
    June 2019 Paper 3, question 2(a)(i): Determine the total volume of urine produced during the first two hours. (1) Answer cm3
  20. Q2(a)(ii)

    June 2019 · Paper 3

    The whole paper ↗
    June 2019 Paper 3, question 2(a)(ii): Explain the role of negative feedback in the control of blood plasma concentration during the first hour after drinking water. (4)
All 31 questions on Osmoregulation and temperature regulation, as a list
  1. June 2025, Paper 2, Q7(c)(i) (2 marks): Calculate the maximum rate that the inulin is removed from the blood. Give your answer to two decimal places with appropriate units. (2) Answer
  2. June 2025, Paper 2, Q7(c)(ii) (2 marks): Explain how inulin passes from the blood plasma into the proximal convoluted tubule of a nephron. (2)
  3. June 2025, Paper 2, Q7(c)(iii) (2 marks): Explain why all the inulin is released into the urine. (2)
  4. June 2024, Paper 2, Q7(b)(i) (4 marks): Explain the changes in core body temperature and skin temperature during exercise, using the information in the graphs. (4)
  5. June 2024, Paper 2, Q7(b)(ii) (1 mark): Mammals are endotherms. Give one method that ectotherms, such as reptiles, can use to thermoregulate. (1)
  6. June 2024, Paper 2, Q7(c) (3 marks): The hypothalamus plays a role in osmoregulation. Describe how stimulation of the hypothalamus leads to the production of concentrated urine. (3)
  7. June 2024, Paper 3, Q2(a)(i) (2 marks): Explain how urea enters the nephron. (2)
  8. June 2024, Paper 3, Q2(a)(ii) (3 marks): In the region labelled A, sodium ions are actively pumped out of the nephron into the surrounding fluid. Explain how this movement of ions results in the format
  9. June 2024, Paper 3, Q2(b)(i) (1 mark): Determine the ratio of urine concentration for these three mammals. (1) Answer
  10. June 2024, Paper 3, Q2(b)(ii) (2 marks): Kangaroo rats live in a desert habitat. Explain one adaptation in the structure of a kangaroo rat kidney that enables it to produce very concentrated urine. (2)
  11. June 2024, Paper 3, Q2(b)(iii) (1 mark): Kangaroo rats are endotherms. Give one behavioural adaptation that you would expect to see in kangaroo rats that helps them to conserve water in a hot desert. (
  12. June 2022, Paper 2, Q6(a) (1 mark): Which labelled parts of this nephron would normally contain glucose? (1) A W only B W and X C W, X, and Y D W, X, Y, and Z
  13. June 2022, Paper 2, Q6(b)(ii) (4 marks): Furosemides are drugs that are used to reduce oedema. They are diuretics that increase urine production. Furosemides reduce the active transport of sodium ions
  14. November 2021, Paper 2, Q6(b)(ii) (6 marks): Capsaicin affects sweat production. It has been suggested that capsaicin could be used to lower the temperature of people with fevers. The effect of three diffe
  15. November 2021, Paper 3, Q7(c)(ii) (4 marks): Explain how, on a very hot day, the brain ensures that the water potential of the blood remains constant. (4)
  16. October 2020, Paper 2, Q3(a) (4 marks): The diagram shows a cell from the proximal convoluted tubule of the nephron. Explain how the features shown in the diagram enable this cell to carry out its fun
  17. October 2020, Paper 2, Q3(b)(ii) (1 mark): The collecting duct is also part of the nephron. Which of the following are the effects of increased release of antidiuretic hormone (ADH)? (1) A decreased perm
  18. October 2020, Paper 3, Q7(c) (4 marks): Wood mice are small mammals. They cannot maintain their body temperature and will die if left in the trap for a long period of time. Explain why wood mice canno
  19. June 2019, Paper 3, Q2(a)(i) (1 mark): Determine the total volume of urine produced during the first two hours. (1) Answer cm3
  20. June 2019, Paper 3, Q2(a)(ii) (4 marks): Explain the role of negative feedback in the control of blood plasma concentration during the first hour after drinking water. (4)
  21. June 2019, Paper 3, Q2(b) (1 mark): The next day the student drank one dm3 of dilute salt solution with the same water potential as blood plasma. The student waited half an hour and collected the
  22. June 2018, Paper 2, Q8(a) (1 mark): Which row of the table names the parts of the kidney labelled in the diagram? (1) W X Y A cortex medulla pelvis B cortex pelvis medulla C medulla pelvis cortex
  23. June 2018, Paper 2, Q8(b) (3 marks): The table shows information about substances found in the blood and in the filtrate in the renal (Bowman’s) capsule. Relative Ratio of concentration in the filt
  24. June 2018, Paper 2, Q8(c) (6 marks): The renal (Bowman’s) capsule is part of each nephron found in the kidney. The graph shows the concentration ratios of three solutes in different parts of the ne
  25. June 2017, Paper 3, Q4(a) (2 marks): Describe how urea is produced in mammals. (2)
  26. June 2017, Paper 3, Q4(b) (1 mark): Bowman’s capsule (renal capsule) in the kidney is involved in the excretion of urea in mammals. Name the cluster of blood capillaries enclosed by Bowman’s capsu
  27. June 2017, Paper 3, Q4(c)(i) (1 mark): Name the process by which this filtrate is produced in Bowman’s capsule. (1)
  28. June 2017, Paper 3, Q4(c)(ii) (3 marks): Analyse the data to explain the difference between the protein and the other molecules or ions in the filtrate in Bowman’s capsule. (3)
  29. June 2017, Paper 3, Q4(c)(iii) (3 marks): Urea and chloride ions both become more concentrated as they pass from Bowman’s capsule to the urine in the bladder. Calculate how many more times urea becomes
  30. June 2017, Paper 3, Q4(c)(iv) (2 marks): Analyse the data to explain the glucose concentration in the bladder. (2)
  31. June 2017, Paper 3, Q4(c)(v) (5 marks): Explain how the loop of Henlé is involved in the production of concentrated urine. (5) .

Questions, mark schemes and examiner’s reports are © Pearson Edexcel, from their published past papers. Plumi isn’t affiliated with any exam board. Want whole papers? Every Edexcel A-Level Biology B paper.

Rather write your answers by hand on iPad? Plumi marks them against the same mark schemes.