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Viruses: Edexcel A‑Level Biology B questions

Every Edexcel A-Level Biology B exam question on 2.2 Viruses, 2016–2025, with its mark scheme and examiner’s report.

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1,826 questions

  1. Q3(a)

    June 2025 · Paper 1

    The whole paper ↗
    June 2025 Paper 1, question 3(a): State why specifically-selected cell types have to be grown in Step 1. (1)
  2. Q3(b)

    June 2025 · Paper 1

    The whole paper ↗
    June 2025 Paper 1, question 3(b): Explain why the flask has to be incubated at an appropriate temperature for a few days in Step 3. (2)
  3. Q3(c)

    June 2025 · Paper 1

    The whole paper ↗
    June 2025 Paper 1, question 3(c): Explain why the viruses and not the cells will be present in the filtrate in Step 5. (3)
  4. Q7(a)

    June 2025 · AS Paper 1

    The whole paper ↗
    June 2025 AS Paper 1, question 7(a): Which of the following statements are correct for Ebola? 1. It contains DNA 2. It has an envelope 3. It is a retrovirus (1) A 1 only B 2 only C 1 and 3 only D 2
  5. Q7(b)

    June 2025 · AS Paper 1

    The whole paper ↗
    June 2025 AS Paper 1, question 7(b): Explain why diseases caused by viruses are difficult to treat. (2)
  6. Q7(c)(i)

    June 2025 · AS Paper 1

    The whole paper ↗
    June 2025 AS Paper 1, question 7(c)(i): State two conclusions that can be made about the outbreaks of Ebola in this time period. (2) 1 2
  7. Q7(c)(ii)

    June 2025 · AS Paper 1

    The whole paper ↗
    June 2025 AS Paper 1, question 7(c)(ii): Give two reasons why the figures presented in this graph are likely to be an underestimate. (2) 1 2
  8. Q7(c)(iii)

    June 2025 · AS Paper 1

    The whole paper ↗
    June 2025 AS Paper 1, question 7(c)(iii): In October 2014, 10 141 cases and 4 922 deaths were reported. Calculate the ratio of cases to deaths. Give your answer in whole numbers. (1) Answer
  9. Q7(d)

    June 2025 · AS Paper 1

    The whole paper ↗
    June 2025 AS Paper 1, question 7(d): The Ebola virus can spread between animals and humans and between humans. The virus is present in bodily fluids of both infected animals and humans. It can be p
  10. Q3(a)

    June 2024 · Paper 1

    The whole paper ↗
    June 2024 Paper 1, question 3(a): Explain why viruses have to be cultured with ‘appropriate cells’. (2)
  11. Q3(b)(i)

    June 2024 · Paper 1

    The whole paper ↗
    June 2024 Paper 1, question 3(b)(i): Explain why the number of viruses did not start to increase until after 20 minutes. (3)
  12. Q3(b)(ii)

    June 2024 · Paper 1

    The whole paper ↗
    June 2024 Paper 1, question 3(b)(ii): Calculate how many more viruses are present at 70 minutes than at 50 minutes. Give your answer to three significant figures. (2) Answer
  13. Q6(a)

    June 2024 · AS Paper 1

    The whole paper ↗
    June 2024 AS Paper 1, question 6(a): The influenza virus has a helical capsid. Which virus also has a helical capsid and an envelope? (1) A Ebola B human immunodeficiency virus C λ (lambda) phage D
  14. Q6(c)

    June 2024 · AS Paper 1

    The whole paper ↗
    June 2024 AS Paper 1, question 6(c): The host cells of the influenza virus are the cells lining the airways. These cells are coated in mucus. Neuraminidase and haemagglutinin are glycoproteins pres
  15. Q4(a)

    June 2023 · Paper 1

    The whole paper ↗
    June 2023 Paper 1, question 4(a): The influenza virus is an RNA virus and has an envelope. Which pair of viruses also have RNA and an envelope? (1) A Ebola and human immunodeficiency virus B Ebo
  16. Q4(d)(ii)

    June 2023 · Paper 1

    The whole paper ↗
    June 2023 Paper 1, question 4(d)(ii): Explain why antibiotics should not be taken by people with viral infections. (2)
  17. Q4(a)

    June 2023 · AS Paper 1

    The whole paper ↗
    June 2023 AS Paper 1, question 4(a): This virus is classified as an enveloped RNA virus with a helical capsid structure. Which virus is also classified in the same way? (1) A Ebola B human immunode
  18. Q4(c)(ii)

    June 2023 · AS Paper 1

    The whole paper ↗
    June 2023 AS Paper 1, question 4(c)(ii): Lectins are molecules that bind to polysaccharides. Some lectins bind to the spikes of this virus. Explain why scientists are hoping that lectins can be used to
  19. Q4(a)

    June 2022 · Paper 1

    The whole paper ↗
    June 2022 Paper 1, question 4(a): Which is a description of a λ phage? (1) A DNA virus with a complex protein capsid B DNA virus with a helical protein capsid C RNA virus with a complex protein
  20. Q4(c)(i)

    June 2022 · Paper 1

    The whole paper ↗
    June 2022 Paper 1, question 4(c)(i): Explain why there was a delay before the number of lysed cells started to increase. (3)
All 56 questions on Viruses, as a list
  1. June 2025, Paper 1, Q3(a) (1 mark): State why specifically-selected cell types have to be grown in Step 1. (1)
  2. June 2025, Paper 1, Q3(b) (2 marks): Explain why the flask has to be incubated at an appropriate temperature for a few days in Step 3. (2)
  3. June 2025, Paper 1, Q3(c) (3 marks): Explain why the viruses and not the cells will be present in the filtrate in Step 5. (3)
  4. June 2025, AS Paper 1, Q7(a) (1 mark): Which of the following statements are correct for Ebola? 1. It contains DNA 2. It has an envelope 3. It is a retrovirus (1) A 1 only B 2 only C 1 and 3 only D 2
  5. June 2025, AS Paper 1, Q7(b) (2 marks): Explain why diseases caused by viruses are difficult to treat. (2)
  6. June 2025, AS Paper 1, Q7(c)(i) (2 marks): State two conclusions that can be made about the outbreaks of Ebola in this time period. (2) 1 2
  7. June 2025, AS Paper 1, Q7(c)(ii) (2 marks): Give two reasons why the figures presented in this graph are likely to be an underestimate. (2) 1 2
  8. June 2025, AS Paper 1, Q7(c)(iii) (1 mark): In October 2014, 10 141 cases and 4 922 deaths were reported. Calculate the ratio of cases to deaths. Give your answer in whole numbers. (1) Answer
  9. June 2025, AS Paper 1, Q7(d) (6 marks): The Ebola virus can spread between animals and humans and between humans. The virus is present in bodily fluids of both infected animals and humans. It can be p
  10. June 2024, Paper 1, Q3(a) (2 marks): Explain why viruses have to be cultured with ‘appropriate cells’. (2)
  11. June 2024, Paper 1, Q3(b)(i) (3 marks): Explain why the number of viruses did not start to increase until after 20 minutes. (3)
  12. June 2024, Paper 1, Q3(b)(ii) (2 marks): Calculate how many more viruses are present at 70 minutes than at 50 minutes. Give your answer to three significant figures. (2) Answer
  13. June 2024, AS Paper 1, Q6(a) (1 mark): The influenza virus has a helical capsid. Which virus also has a helical capsid and an envelope? (1) A Ebola B human immunodeficiency virus C λ (lambda) phage D
  14. June 2024, AS Paper 1, Q6(c) (6 marks): The host cells of the influenza virus are the cells lining the airways. These cells are coated in mucus. Neuraminidase and haemagglutinin are glycoproteins pres
  15. June 2023, Paper 1, Q4(a) (1 mark): The influenza virus is an RNA virus and has an envelope. Which pair of viruses also have RNA and an envelope? (1) A Ebola and human immunodeficiency virus B Ebo
  16. June 2023, Paper 1, Q4(d)(ii) (2 marks): Explain why antibiotics should not be taken by people with viral infections. (2)
  17. June 2023, AS Paper 1, Q4(a) (1 mark): This virus is classified as an enveloped RNA virus with a helical capsid structure. Which virus is also classified in the same way? (1) A Ebola B human immunode
  18. June 2023, AS Paper 1, Q4(c)(ii) (3 marks): Lectins are molecules that bind to polysaccharides. Some lectins bind to the spikes of this virus. Explain why scientists are hoping that lectins can be used to
  19. June 2022, Paper 1, Q4(a) (1 mark): Which is a description of a λ phage? (1) A DNA virus with a complex protein capsid B DNA virus with a helical protein capsid C RNA virus with a complex protein
  20. June 2022, Paper 1, Q4(c)(i) (3 marks): Explain why there was a delay before the number of lysed cells started to increase. (3)
  21. June 2022, Paper 1, Q4(c)(ii) (2 marks): Calculate the mean rate of increase in the actual number of lysed cells between 50 minutes and 90 minutes. (2) Answer cells min–1
  22. June 2022, Paper 1, Q4(c)(iii) (2 marks): A sketch has been made of this growth curve. Log10 number of lysed cells Time after adding viruses to cells Complete this sketch to predict the shape of the gro
  23. November 2021, Paper 1, Q8(a) (3 marks): Compare and contrast the structure of a bacterial cell with the structure of HPV. (3)
  24. November 2021, Paper 2, Q5(b)(i) (2 marks): Analyse the graph to determine the approximate mutation rate for tobacco mosaic virus (TMV). (2) Answer
  25. November 2021, AS Paper 1, Q5(a)(i) (1 mark): Which virus has both a polyhedral capsid and an envelope? (1) A Ebola B human immunodeficiency virus C λ (lambda) phage D tobacco mosaic virus
  26. November 2021, AS Paper 1, Q5(a)(ii) (1 mark): State what the genes in the DNA of EBV code for, other than glycoproteins. (1)
  27. November 2021, AS Paper 1, Q5(a)(iii) (2 marks): Describe the role of the glycoproteins in EBV. (2)
  28. November 2021, AS Paper 1, Q5(b) (2 marks): Complete the graph to show the shape of the growth curve of EBV as a result of one lytic cycle after infection of a cell. (2) Number of viruses in the cell numb
  29. November 2021, AS Paper 1, Q5(c)(i) (2 marks): There were 47% boys in this group of children. Calculate the number of girls in this group of children. (2) Answer
  30. November 2021, AS Paper 1, Q5(c)(ii) (2 marks): Determine the effect of age on the proportion of children with non-typical symptoms of EBV. (2)
  31. November 2021, AS Paper 1, Q5(c)(iii) (3 marks): Describe how this investigation could be improved. (3)
  32. October 2020, Paper 1, Q6(a) (3 marks): The table shows some features used to classify viruses. Which box in each row shows how these viruses are classified? (3) Classification of viruses Virus DNA DN
  33. October 2020, Paper 1, Q6(b) (3 marks): One study into the causes of gastroenteritis involved 162 patients. This study found that 24.7% of these gastroenteritis cases were caused by viruses. The pie c
  34. October 2020, Paper 1, Q6(c) (3 marks): Norovirus is usually spread through the faecal-oral route. The diagram shows the pathway that norovirus takes through the body. 1 The norovirus is transmitted
  35. October 2020, Paper 1, Q6(d)(i) (3 marks): Animals infected with stealth spheres develop gastroenteritis very quickly and with severe symptoms. Animals infected with individual noroviruses develop gastro
  36. October 2020, Paper 1, Q6(d)(ii) (2 marks): Scientists are hoping that new treatments for norovirus infections can be developed to target the stealth sphere. Analyse the information to explain how targeti
  37. June 2019, Paper 2, Q3(a) (1 mark): Which of the following viruses contains RNA and the enzyme reverse transcriptase? (1) A Ebola virus B human immunodeficiency virus (HIV) C λ (lambda) phage D to
  38. June 2019, Paper 2, Q3(b)(i) (2 marks): Describe the lytic cycle of a virus. (2)
  39. June 2019, Paper 2, Q3(b)(ii) (2 marks): Some doctors believe that the Ebola virus may undergo latency within body cells. State what is meant by the term latency. (2)
  40. June 2019, Paper 2, Q3(c) (4 marks): An experimental drug called Zmapp was used to treat patients during this outbreak of Ebola virus. Patients with Ebola virus were randomly split into two groups.
  41. June 2018, Paper 2, Q4(a)(ii) (1 mark): Which virus contains DNA? (1) A Ebola B HIV C λ (lambda) phage D tobacco mosaic
  42. June 2018, AS Paper 1, Q2(b)(ii) (2 marks): Explain why viruses are not affected by antibiotics. (2)
  43. June 2018, AS Paper 1, Q8(a) (2 marks): Explain why viruses are dependent on living cells. (2)
  44. June 2018, AS Paper 1, Q8(b)(i) (6 marks): Analyse the information in the graph and maps to comment on the spread of Ebola in West Africa. (6)
  45. June 2018, AS Paper 1, Q8(b)(ii) (3 marks): Describe the methods used to prevent the spread of Ebola. (3)
  46. June 2018, AS Paper 1, Q8(c) (4 marks): During this outbreak of Ebola, no vaccine had been developed. The World Health Organisation recommended that untested antiviral drugs could be used to treat pat
  47. June 2017, Paper 1, Q3(b)(i) (1 mark): The following four statements are features of viruses: 1. have envelopes 2. contain reverse transcriptase 3. surrounded by a protein coat 4. have a helical stru
  48. June 2017, Paper 1, Q3(b)(ii) (1 mark): Which of the following groups of viruses are also RNA viruses? (1) A Ebola virus, human immunodeficiency virus and tobacco mosaic virus B Ebola virus, Ȝ phage a
  49. June 2017, Paper 3, Q6(a) (2 marks): Calculate the percentage increase in the number of babies born with microcephaly in 2015 compared with 2014. (2) Answer %
  50. June 2017, Paper 3, Q6(b)(i) (2 marks): Explain why another type of drug, rather than antibiotics, has to be used to treat Zika virus infections. (2)
  51. June 2017, Paper 3, Q6(b)(iii) (2 marks): Explain why the Brazilian government has advised people to use mosquito nets, even if they have already contracted the Zika virus. (2)
  52. June 2017, Paper 3, Q6(c)(ii) (2 marks): Unlike human immunodeficiency virus (HIV), Zika is not a retrovirus. Describe what happens to the Zika RNA once it is in the cell. (2)
  53. June 2017, AS Paper 1, Q6(a)(i) (1 mark): Which of the following pairs of viruses both have an envelope? (1) A Ebola and λ (lambda) phage B human immunodeficiency virus and Ebola C λ (lambda) phage and
  54. June 2017, AS Paper 1, Q6(a)(ii) (1 mark): Which of the following pairs of viruses both have a helical capsid? (1) A Ebola and tobacco mosaic virus B λ (lambda) phage and Ebola C human immunodeficiency v
  55. June 2017, AS Paper 1, Q6(b)(i) (3 marks): Describe the lytic cycle of a virus. (3)
  56. June 2017, AS Paper 1, Q6(b)(ii) (3 marks): The multiplicity of infection (MOI) is one factor that determines whether a virus enters the lytic cycle or latency. MOI = number of infectious virus particles

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