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Acyl chlorides in synthesis: OCR A‑Level Chemistry A questions

OCR A-Level Chemistry A past-paper questions on 6.1.3.3 Acyl chlorides in synthesis, 2016–2025, with mark schemes and examiner’s reports where available.

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  2. Q18(c)

    June 2025 · Paper 2

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  4. Q20(b)(ii)

    June 2024 · Paper 2

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  5. Q12

    June 2023 · Paper 2

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  7. Q20(f)

    June 2022 · Paper 2

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  9. Q18(b)(iii)

    November 2020 · Paper 2

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  12. Q13

    June 2017 · Paper 2

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All 12 questions on Acyl chlorides in synthesis, as a list
  1. June 2025, Paper 2, Q9 (1 mark): Which reagents could a student use to prepare the ester shown? O CH3CH2 C O O A OH CH3CH2 C + HO CH3CH2 OH + HOOC B C CH3CH2CH2 OH + HOOC O D CH3CH2 C Cl + HO Y
  2. June 2025, Paper 2, Q18(c) (2 marks): 3-Hydroxybutanoic acid reacts with ethanoic anhydride, (CH3CO)2O. Complete the equation for this reaction. Show the structures of the organic compounds. CH3 O O
  3. June 2025, Paper 2, Q21(e) (7 marks): Complete the flowchart for the reactions of pyruvic acid. excess NH3 Acyl chloride Compound P reagent(s) O NaOH(aq) O OH Pyruvic acid CH3OH / H2SO4 reagent(s) O
  4. June 2024, Paper 2, Q20(b)(ii) (4 marks): Ester F can be prepared from a carboxylic acid in two steps. Step 1 The carboxylic acid is converted into an acyl chloride. Step 2 The acyl chloride is converte
  5. June 2023, Paper 2, Q12 (1 mark): Which compound reacts with ethanoyl chloride? O A O B O Cl C O D NH2 O Your answer [1]
  6. June 2023, Paper 2, Q20(a) (4 marks): Salicylic acid, shown below, is used in the manufacture of some important medicines. COOH OH Salicylic acid Complete the flowchart for reactions of salicylic ac
  7. June 2022, Paper 2, Q20(f) (2 marks): Acid anhydrides react in a similar way to acyl chlorides with phenols. Benzoic anhydride is the acid anhydride of benzoic acid, C6H5COOH. Benzoic anhydride reac
  8. November 2021, Paper 3, Q5(c) (6 marks): This question is about nitrogen and its compounds. (c)* This question is about two reactions of ammonia. Reaction 1 Excess ammonia is reacted with 4.77 g of cop
  9. November 2020, Paper 2, Q18(b)(iii) (3 marks): A large yield of polymer E can be obtained by reacting a diacyl dichloride with HO(CH2)4OH. The diacyl dichloride is prepared from HOOC(CH2)2COOH. Complete the
  10. June 2018, Paper 2, Q21(b) (4 marks): Compound H is used in the synthesis of polymer I, as shown in the flowchart below. Complete the flowchart by drawing the structure of the acyl chloride and two
  11. June 2017, Paper 2, Q10 (1 mark): Equal amounts of the four compounds are added to the same volume of water. Which compound would produce the most acidic solution? A CH3CONH2 B CH3COOH C CH3COOC
  12. June 2017, Paper 2, Q13 (1 mark): Which reagents could be used to prepare CH3CH2CONHCH3? A CH3CH2COCl + CH3NH2 B CH3CH2CONH2 + CH3Br C CH3CH2COONa + CH3NH2 D CH3CH2COCH3 + NH3 Your answer [1]

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