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CAIE A‑Level Biology questions by topic

Every question from the CAIE AS & A Level Biology (9700) papers Cambridge International publishes, June 2024 and the specimen papers, part by part. Cambridge keeps its other papers on its School Support Hub, for schools. Filter by topic or paper, open the mark scheme under any question, and download a set as a PDF.

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Year 1 · AS

Year 2 · A‑Level only

Calculations

240 questions

  1. Q1(a)

    June 2024 · Paper 4

    3 marks
    The whole paper ↗
    June 2024 Paper 4, question 1(a): Fig. 1.1 shows a transmission electron micrograph of a mitochondrion. A B C D Fig. 1.1 Table 1.1 lists the four stages of aerobic respiration. With reference to
  2. Q1(b)

    June 2024 · Paper 4

    4 marks
    The whole paper ↗
    June 2024 Paper 4, question 1(b): In anaerobic conditions, no ATP can be synthesised by oxidative phosphorylation because the process stops. Explain why ATP synthesis by oxidative phosphorylatio
  3. Q1(c)

    June 2024 · Paper 4

    3 marks
    The whole paper ↗
    June 2024 Paper 4, question 1(c): Up to 60% of the ATP that is produced in cancer cells comes from lactate fermentation of glucose, even though oxygen is present. Scientists are developing cance
  4. Q2(a)(i)

    June 2024 · Paper 4

    2 marks
    The whole paper ↗
    June 2024 Paper 4, question 2(a)(i): Identify one similarity and one difference between paracrine cell signalling and cell signalling that occurs as part of the endocrine system. [2]
  5. Q2(a)(ii)

    June 2024 · Paper 4

    2 marks
    The whole paper ↗
    June 2024 Paper 4, question 2(a)(ii): Explain why a neurotransmitter such as acetylcholine could be described as a paracrine signalling molecule. [2]
  6. Q2(b)

    June 2024 · Paper 4

    3 marks
    The whole paper ↗
    June 2024 Paper 4, question 2(b): Human muscle cells show paracrine signalling. After muscle cells have been exposed to a substance called palmitate they: • produce a signalling molecule • show
  7. Q2(c)

    June 2024 · Paper 4

    3 marks
    The whole paper ↗
    June 2024 Paper 4, question 2(c): The process of protein translation is inhibited in developing muscle cells when stress genes are expressed. Suggest how developing muscle cells that express str
  8. Q3(a)

    June 2024 · Paper 4

    4 marks
    The whole paper ↗
    June 2024 Paper 4, question 3(a): Describe the mechanism by which stomata open in sunlight. [4]
  9. Q3(b)(i)

    June 2024 · Paper 4

    2 marks
    The whole paper ↗
    June 2024 Paper 4, question 3(b)(i): With reference to Fig. 3.1, describe the relationship between the concentration of ABA in the xylem sap and stomatal conductance. [2]
  10. Q3(b)(ii)

    June 2024 · Paper 4

    4 marks
    The whole paper ↗
    June 2024 Paper 4, question 3(b)(ii): Suggest explanations for the results shown in Fig. 3.1. [4]
  11. Q3(c)

    June 2024 · Paper 4

    1 mark
    The whole paper ↗
    June 2024 Paper 4, question 3(c): Some transcription factors increase the rate of transcription of genes involved in the closure of stomata. State where transcription factors bind to cause an in
  12. Q4(a)

    June 2024 · Paper 4

    4 marks
    The whole paper ↗
    June 2024 Paper 4, question 4(a): North American P. leniusculus can carry the crayfish plague pathogen without showing symptoms because they have evolved resistance to it. Explain how P. leniusc
  13. Q4(b)(i)

    June 2024 · Paper 4

    4 marks
    The whole paper ↗
    June 2024 Paper 4, question 4(b)(i): Outline and explain the steps that occur in PCR. [4]
  14. Q4(b)(ii)

    June 2024 · Paper 4

    1 mark
    The whole paper ↗
    June 2024 Paper 4, question 4(b)(ii): Suggest how the researchers were able to discover suitable sequences for the primers. [1]
  15. Q4(c)(i)

    June 2024 · Paper 4

    1 mark
    The whole paper ↗
    June 2024 Paper 4, question 4(c)(i): State the letter of the curve with the highest starting concentration of DNA. [1]
  16. Q4(c)(ii)

    June 2024 · Paper 4

    1 mark
    The whole paper ↗
    June 2024 Paper 4, question 4(c)(ii): The quantity of A. pallipes DNA reaches a threshold (marked as a horizontal line on Fig. 4.1) at 28 cycles. The DNA in curve C reaches the threshold after 25 cy
  17. Q4(d)(i)

    June 2024 · Paper 4

    3 marks
    The whole paper ↗
    June 2024 Paper 4, question 4(d)(i): Identify the component that is taken up by normal bacteria to produce the genetically modified bacteria in Fig. 4.2 and state what this component contains to al
  18. Q4(d)(ii)

    June 2024 · Paper 4

    1 mark
    The whole paper ↗
    June 2024 Paper 4, question 4(d)(ii): Suggest why the gene for green fluorescent protein is sometimes transferred in addition to the desired gene in genetic engineering. [1] [Total: 15]
  19. Q5(a)(i)

    June 2024 · Paper 4

    2 marks
    The whole paper ↗
    June 2024 Paper 4, question 5(a)(i): A and B are areas of the chloroplast. Name areas A and B. A B [2]
  20. Q5(a)(ii)

    June 2024 · Paper 4

    2 marks
    The whole paper ↗
    June 2024 Paper 4, question 5(a)(ii): The group of proteins labelled C, PSI and the protein labelled E are involved in a specific biochemical process during the light‑dependent stage of photosynthes

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