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The immune system and immunisation: Edexcel GCSE Biology questions

Every Edexcel GCSE Biology exam question on The immune system and immunisation (specification points 5.12–5.15), 2018–2025, with its mark scheme and examiner’s report.

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1,834 questions

  1. Q6(b)

    June 2025 · Paper 1 Higher

    The whole paper ↗
    June 2025 Paper 1 Higher, question 6(b): Describe the specific immune response when a pathogen infects the body. (3)
  2. Q7(a)(ii)

    June 2025 · Paper 1 Foundation

    The whole paper ↗
    June 2025 Paper 1 Foundation, question 7(a)(ii): In the UK, most children are immunised against serious infections such as measles. Give two advantages of immunising children against measles. (2) 1 2
  3. Q7(b)(i)

    June 2025 · Paper 1 Foundation

    The whole paper ↗
    June 2025 Paper 1 Foundation, question 7(b)(i): Name two of these physical barriers. (2) 1 2
  4. Q7(b)(ii)

    June 2025 · Paper 1 Foundation

    The whole paper ↗
    June 2025 Paper 1 Foundation, question 7(b)(ii): State the chemical in the stomach that destroys bacteria. (1)
  5. Q2(a)

    June 2025 · Paper 2 Higher

    The whole paper ↗
    June 2025 Paper 2 Higher, question 2(a): Figure 2 shows a diagram of mucus‑producing goblet cells and ciliated epithelial cells in the airways of the lungs. ciliated epithelial mucus-producing cell gob
  6. Q8(b)

    June 2025 · Paper 2 Foundation

    The whole paper ↗
    June 2025 Paper 2 Foundation, question 8(b): Figure 16 shows a diagram of mucus‑producing goblet cells and ciliated epithelial cells in the airways of the lungs. ciliated epithelial mucus-producing cell go
  7. Q3(b)

    June 2024 · Paper 1 Higher

    The whole paper ↗
    June 2024 Paper 1 Higher, question 3(b): Measles is a disease caused by a virus. Figure 4 shows the number of measles cases reported in England and Wales from 1985 to 2015. year number of measles cases
  8. Q3(c)

    June 2024 · Paper 1 Higher

    The whole paper ↗
    June 2024 Paper 1 Higher, question 3(c): Describe two ways the immune system will respond to an infection by a pathogen. (2) 1 2
  9. Q1(b)

    June 2024 · Paper 1 Foundation

    The whole paper ↗
    June 2024 Paper 1 Foundation, question 1(b): The human body has defences to protect against infection by bacteria. Draw one straight line from each body defence to its function. (2) body defence function m
  10. Q9(b)

    June 2024 · Paper 1 Foundation

    The whole paper ↗
    June 2024 Paper 1 Foundation, question 9(b): Measles is a disease caused by a virus. Figure 17 shows the number of measles cases reported in England and Wales from 1985 to 2015. year number of measles case
  11. Q9(c)

    June 2024 · Paper 1 Foundation

    The whole paper ↗
    June 2024 Paper 1 Foundation, question 9(c): Describe two ways the immune system will respond to an infection by a pathogen. (2) 1 2
  12. Q9(b)

    June 2022 · Paper 1 Foundation

    The whole paper ↗
    June 2022 Paper 1 Foundation, question 9(b): When a person is infected with a disease, the immune system will respond to protect their body. Explain how the immune system will respond to an infection cause
  13. Q9(c)

    November 2021 · Paper 1 Foundation

    The whole paper ↗
    November 2021 Paper 1 Foundation, question 9(c): Describe how the physical barriers and chemical defences of the human body provide protection from diseases. (6)
  14. Q9(a)(ii)

    November 2021 · Paper 2 Foundation

    The whole paper ↗
    November 2021 Paper 2 Foundation, question 9(a)(ii): State the function of the ciliated epithelial cells in the airways of the human breathing system. (1)
  15. Q2(b)

    November 2020 · Paper 1 Higher

    The whole paper ↗
    November 2020 Paper 1 Higher, question 2(b): Describe how the specific immune system defends the body against disease. (3)
  16. Q2(c)(iii)

    November 2020 · Paper 1 Higher

    The whole paper ↗
    November 2020 Paper 1 Higher, question 2(c)(iii): Give one reason why the number of people per million diagnosed with measles is different in these countries. (1)
  17. Q8(c)

    November 2020 · Paper 1 Foundation

    The whole paper ↗
    November 2020 Paper 1 Foundation, question 8(c): Describe how the specific immune system defends the body against disease. (3)
  18. Q8(d)(iii)

    November 2020 · Paper 1 Foundation

    The whole paper ↗
    November 2020 Paper 1 Foundation, question 8(d)(iii): Give one reason why the number of people per million diagnosed with measles is different in these countries. (1)
  19. Q3(a)

    June 2019 · Paper 1 Higher

    The whole paper ↗
    June 2019 Paper 1 Higher, question 3(a): Clostridium tetani is a bacterium that can be found in soil. It causes the infection tetanus. Children are vaccinated against tetanus. Explain why these childre
  20. Q7(c)(i)

    June 2019 · Paper 1 Higher

    The whole paper ↗
    June 2019 Paper 1 Higher, question 7(c)(i): State two reasons why people might not be immunised against measles. (2) 1 2
All 24 questions on The immune system and immunisation, as a list
  1. June 2025, Paper 1 Higher, Q6(b) (3 marks): Describe the specific immune response when a pathogen infects the body. (3)
  2. June 2025, Paper 1 Foundation, Q7(a)(ii) (2 marks): In the UK, most children are immunised against serious infections such as measles. Give two advantages of immunising children against measles. (2) 1 2
  3. June 2025, Paper 1 Foundation, Q7(b)(i) (2 marks): Name two of these physical barriers. (2) 1 2
  4. June 2025, Paper 1 Foundation, Q7(b)(ii) (1 mark): State the chemical in the stomach that destroys bacteria. (1)
  5. June 2025, Paper 2 Higher, Q2(a) (2 marks): Figure 2 shows a diagram of mucus‑producing goblet cells and ciliated epithelial cells in the airways of the lungs. ciliated epithelial mucus-producing cell gob
  6. June 2025, Paper 2 Foundation, Q8(b) (2 marks): Figure 16 shows a diagram of mucus‑producing goblet cells and ciliated epithelial cells in the airways of the lungs. ciliated epithelial mucus-producing cell go
  7. June 2024, Paper 1 Higher, Q3(b) (2 marks): Measles is a disease caused by a virus. Figure 4 shows the number of measles cases reported in England and Wales from 1985 to 2015. year number of measles cases
  8. June 2024, Paper 1 Higher, Q3(c) (2 marks): Describe two ways the immune system will respond to an infection by a pathogen. (2) 1 2
  9. June 2024, Paper 1 Foundation, Q1(b) (2 marks): The human body has defences to protect against infection by bacteria. Draw one straight line from each body defence to its function. (2) body defence function m
  10. June 2024, Paper 1 Foundation, Q9(b) (2 marks): Measles is a disease caused by a virus. Figure 17 shows the number of measles cases reported in England and Wales from 1985 to 2015. year number of measles case
  11. June 2024, Paper 1 Foundation, Q9(c) (2 marks): Describe two ways the immune system will respond to an infection by a pathogen. (2) 1 2
  12. June 2022, Paper 1 Foundation, Q9(b) (6 marks): When a person is infected with a disease, the immune system will respond to protect their body. Explain how the immune system will respond to an infection cause
  13. November 2021, Paper 1 Foundation, Q9(c) (6 marks): Describe how the physical barriers and chemical defences of the human body provide protection from diseases. (6)
  14. November 2021, Paper 2 Foundation, Q9(a)(ii) (1 mark): State the function of the ciliated epithelial cells in the airways of the human breathing system. (1)
  15. November 2020, Paper 1 Higher, Q2(b) (3 marks): Describe how the specific immune system defends the body against disease. (3)
  16. November 2020, Paper 1 Higher, Q2(c)(iii) (1 mark): Give one reason why the number of people per million diagnosed with measles is different in these countries. (1)
  17. November 2020, Paper 1 Foundation, Q8(c) (3 marks): Describe how the specific immune system defends the body against disease. (3)
  18. November 2020, Paper 1 Foundation, Q8(d)(iii) (1 mark): Give one reason why the number of people per million diagnosed with measles is different in these countries. (1)
  19. June 2019, Paper 1 Higher, Q3(a) (3 marks): Clostridium tetani is a bacterium that can be found in soil. It causes the infection tetanus. Children are vaccinated against tetanus. Explain why these childre
  20. June 2019, Paper 1 Higher, Q7(c)(i) (2 marks): State two reasons why people might not be immunised against measles. (2) 1 2
  21. June 2019, Paper 1 Higher, Q7(c)(ii) (2 marks): The spread of measles is prevented by herd immunity. Describe herd immunity. (2)
  22. June 2019, Paper 1 Foundation, Q9(a) (3 marks): Clostridium tetani is a bacterium that can be found in soil. It causes the infection tetanus. Children are vaccinated against tetanus. Explain why these childre
  23. June 2018, Paper 1 Higher, Q5(c) (3 marks): Most cases of scarlet fever occur in children. Adults have usually developed immunity to a toxin that the Streptococcus bacteria produce during infection. Expla
  24. Specimen, Paper 1 Foundation, Q6(a)(ii) (2 marks): Describe how the conjunctiva helps protects the eye from infection. (2) Cataracts are caused by cloudy patches that develop on the lens. The chance of being aff

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