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Monoclonal antibodies: Edexcel GCSE Biology questions

Every Edexcel GCSE Biology exam question on Monoclonal antibodies (specification points 5.21–5.22), 2018–2025, with its mark scheme and examiner’s report.

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1,834 questions

  1. Q7(c)

    June 2025 · Paper 1 Higher

    6 marksMonoclonal antibodies
    Mark scheme (PDF)
    The whole paper ↗
    June 2025 Paper 1 Higher, question 7(c): Some monoclonal antibodies have been approved for use in the diagnosis of blood clots. Explain how monoclonal antibodies are produced and how they can be used i

  2. Q10(c)

    June 2023 · Paper 1 Higher

    4 marksMonoclonal antibodies
    The whole paper ↗
    June 2023 Paper 1 Higher, question 10(c): Monoclonal antibodies can be used in the diagnosis of genetic disorders and pregnancy testing. Describe how a pregnancy test uses monoclonal antibodies to show

  3. Q10(b)(i)

    November 2021 · Paper 1 Higher

    1 markMonoclonal antibodies
    The whole paper ↗
    November 2021 Paper 1 Higher, question 10(b)(i): Which type of cell is added to the B lymphocytes to produce the hybridoma? (1) A phagocytic cell B red blood cell C cancer cell D epithelial cell

  4. Q10(b)(ii)

    November 2021 · Paper 1 Higher

    3 marksMonoclonal antibodies
    The whole paper ↗
    November 2021 Paper 1 Higher, question 10(b)(ii): A person with blood group A has the A antigen on the surface of their red blood cells. Monoclonal antibodies can be used to detect the A antigen on red blood ce

  5. Q10(b)

    Specimen · Paper 1 Higher

    6 marksMonoclonal antibodies
    The whole paper ↗
    Specimen Paper 1 Higher, question 10(b): Some sexually transmitted infections (STIs) can be diagnosed by testing urine samples. These tests use monoclonal antibodies that bind to an antigen on the path
All 5 questions on Monoclonal antibodies, as a list
  1. June 2025, Paper 1 Higher, Q7(c) (6 marks): Some monoclonal antibodies have been approved for use in the diagnosis of blood clots. Explain how monoclonal antibodies are produced and how they can be used i
  2. June 2023, Paper 1 Higher, Q10(c) (4 marks): Monoclonal antibodies can be used in the diagnosis of genetic disorders and pregnancy testing. Describe how a pregnancy test uses monoclonal antibodies to show
  3. November 2021, Paper 1 Higher, Q10(b)(i) (1 mark): Which type of cell is added to the B lymphocytes to produce the hybridoma? (1) A phagocytic cell B red blood cell C cancer cell D epithelial cell
  4. November 2021, Paper 1 Higher, Q10(b)(ii) (3 marks): A person with blood group A has the A antigen on the surface of their red blood cells. Monoclonal antibodies can be used to detect the A antigen on red blood ce
  5. Specimen, Paper 1 Higher, Q10(b) (6 marks): Some sexually transmitted infections (STIs) can be diagnosed by testing urine samples. These tests use monoclonal antibodies that bind to an antigen on the path

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