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Protein production and secretion: OCR A‑Level Biology A questions

OCR A-Level Biology A past-paper questions on 2.1.1.4 Protein production and secretion, 2016–2025, with mark schemes and examiner’s reports where available.

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  2. Q21(a)

    June 2024 · Paper 1

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  3. Q5(c)(ii)

    June 2024 · AS Paper 2

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  4. Q8

    June 2023 · AS Paper 1

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  5. Q3

    November 2021 · Paper 1

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  6. Q21(b)(iii)

    November 2021 · AS Paper 1

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  7. Q2(a)(ii)

    November 2020 · AS Paper 2

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  8. Q2(b)(i)

    November 2020 · AS Paper 2

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  9. Q1

    June 2018 · AS Paper 1

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  10. Q20(e)

    June 2017 · Paper 1

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  11. Q22(b)

    June 2017 · AS Paper 1

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All 11 questions on Protein production and secretion, as a list
  1. June 2025, AS Paper 1, Q23(a)(iii) (3 marks): Using the diagram and your own knowledge, explain why plasma cells are usually larger than B lymphocytes. [3]
  2. June 2024, Paper 1, Q21(a) (3 marks): Most digestive enzymes are extracellular. Complete the sentences about the synthesis and secretion of a typical digestive enzyme using the most appropriate term
  3. June 2024, AS Paper 2, Q5(c)(ii) (4 marks): Describe how the rough endoplasmic reticulum and the Golgi apparatus are involved in the production of a secretory vesicle that contains protein. [4]
  4. June 2023, AS Paper 1, Q8 (1 mark): What is the pathway taken by a protein that has been made and is to be secreted from a cell? A Ribosome vesicle Golgi apparatus cytoplasm B Ribosome vesicle rou
  5. November 2021, Paper 1, Q3 (1 mark): Which of the options describes the path taken by proteins, such as digestive enzymes, that are exported from a cell? A Golgi apparatus rough endoplasmic reticul
  6. November 2021, AS Paper 1, Q21(b)(iii) (2 marks): Suggest two ways tubulin is essential to protein synthesis and protein secretion in eukaryotic cells. 1 2 [2]
  7. November 2020, AS Paper 2, Q2(a)(ii) (2 marks): Suggest how the role of the cellular component labelled B is relevant to the function of the goblet cell. [2]
  8. November 2020, AS Paper 2, Q2(b)(i) (2 marks): Mucus is present in goblet cells as condensed granules. Some studies reveal that when secreted, the mucus expands to 500 times its volume in 20 ms. 40 cm3 of mu
  9. June 2018, AS Paper 1, Q1 (1 mark): Which organelle, A to D, is not involved in the production and secretion of enzymes in eukaryotes? A golgi apparatus B ribosomes C smooth endoplasmic reticulum
  10. June 2017, Paper 1, Q20(e) (1 mark): Anaerobic respiration in yeast cells requires enzymes. Which organelle is responsible for synthesising these enzymes? [1]
  11. June 2017, AS Paper 1, Q22(b) (3 marks): Humans use the enzyme α-amylase to break down polysaccharides in food for absorption into the blood. The gene for human α-amylase is found on chromosome 1. The

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