Antibodies: OCR A‑Level Biology A questions
OCR A-Level Biology A past-paper questions on 4.1.1.5 Antibodies, 2016–2025, with mark schemes and examiner’s reports where available.
Paper
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Calculations
Q7(b)(iv)
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- Your answer
Q19(c)(ii)
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Q5(b)(iv)
The whole paper ↗Q1(a)
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- Your answer
- Your answer
Q22(b)
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Q3(c)
The whole paper ↗Q4(c)
The whole paper ↗- Your answer
Q3(c)(ii)
The whole paper ↗- Your answer
All 14 questions on Antibodies, as a list
- June 2025, Paper 3, Q7(b)(iv) (1 mark): Antibodies can bind to receptors on the cell surface membrane of a neutrophil. The binding of an antibody to a receptor causes the neutrophil to engulf the path
- June 2025, AS Paper 1, Q15 (1 mark): The diagram shows an antibody attached to multiple pathogens. Pathogen Antibody What is the type of antibody shown? A Agglutinin B Antigen C Anti-toxin D Opsoni
- June 2023, Paper 2, Q19(c)(ii) (3 marks): Fig. 19.2 shows the structure of a Fab fragment. Fig. 19.2 Identify two similarities and one difference in structure between a Fab fragment and a whole antibody
- June 2023, AS Paper 1, Q2 (1 mark): The diagram shows a computer model of the structure of an antibody. A B C Constant region D Which part of the antibody, A, B, C or D, is an antigen-binding site
- June 2023, AS Paper 2, Q5(b)(iv) (2 marks): A student wrote the following passage about the immune system: ‘T helper cells produce cell signalling molecules called perforins. These stimulate the activity
- June 2022, Paper 3, Q1(a) (3 marks): Fig. 1.1 shows the roles of three different types of antibody, labelled R, S and T. R S Pathogen Pathogen Antibody Receptor White Antibody blood cell T Antibody
- November 2021, Paper 2, Q5 (1 mark): Antibodies form part of the immune response. Which of the following types of antibody bind to antigens on the surface of pathogens? 1 opsonins 2 agglutinins 3 a
- November 2021, AS Paper 1, Q14 (1 mark): The image below shows an antibody structure with the parts labelled P to T. P P Q S R T Which row, A to D, correctly identifies the parts of the antibody struct
- November 2020, Paper 2, Q22(b) (2 marks): Phagocytosis involves cytokines and opsonins. State the role of cytokines and opsonins in phagocytosis. cytokines opsonins [2]
- November 2020, AS Paper 2, Q3(c) (2 marks): Some people are immune to malaria. They produce a specific type of antibody. One way in which antibodies defend the body is by acting as agglutinins. Outline th
- June 2019, Paper 3, Q4(c) (2 marks): It is possible to manufacture antibodies to treat certain diseases. These are known as synthetic antibodies. DNL-Fab3, shown in Fig. 4.2, is an example of a syn
- June 2018, Paper 2, Q8 (1 mark): Which of the following antibodies increase(s) the phagocytosis of pathogens? 1 opsonins 2 agglutinins 3 anti-toxins A 1, 2 and 3 B Only 1 and 2 C Only 2 and 3 D
- June 2018, AS Paper 2, Q3(c)(ii) (1 mark): Antibodies are defensive proteins carried in the bloodstream. Fig. 3.2 shows the simplified, incomplete structure of an antibody. Complete Fig. 3.2 by drawing a
- June 2016, AS Paper 1, Q15 (1 mark): The diagram below shows the simplified structure of an antibody. A B C D Which of the letters, A to D identifies the region of the antibody that allows the dist
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