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Meiosis and genetic variation: Edexcel International A Level Biology questions

Edexcel International A Level Biology past-paper questions on 3.3.2 Meiosis and genetic variation, 2019–2025, with mark schemes and examiner’s reports where available.

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  1. Q3(b)(i)

    June 2025 · AS Unit 2

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  2. Q3(b)(ii)

    June 2025 · AS Unit 2

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  3. Q5(a)

    January 2025 · AS Unit 2

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  4. Q6(b)(i)

    October 2024 · AS Unit 2

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  5. Q6(c)

    October 2024 · AS Unit 2

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  6. Q7(a)

    June 2024 · AS Unit 2

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  7. Q1(b)

    October 2023 · AS Unit 2

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  8. Q1(c)

    October 2023 · AS Unit 2

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  10. Q6(a)(i)

    June 2023 · AS Unit 2

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  11. Q6(a)(ii)

    June 2023 · AS Unit 2

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  14. Q2(a)(i)

    January 2023 · AS Unit 2

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  15. Q2(a)(ii)

    January 2023 · AS Unit 2

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  16. Q8(a)(i)

    January 2023 · AS Unit 2

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  17. Q6(a)(i)

    October 2022 · AS Unit 2

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  18. Q4(b)(ii)

    June 2022 · AS Unit 2

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  20. Q7(a)

    October 2021 · AS Unit 2

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All 32 questions on Meiosis and genetic variation, as a list
  1. June 2025, AS Unit 2, Q3(b)(i) (1 mark): Name the stage of meiosis when crossing over of chromatids occurs. (1)
  2. June 2025, AS Unit 2, Q3(b)(ii) (2 marks): Describe two other processes that can give rise to genetic variation in the offspring of the passion flower. (2) 1 2
  3. January 2025, AS Unit 2, Q5(a) (3 marks): Complete this graph to show how the DNA content per cell would change when a cell, with 2 a.u. of DNA, undergoes meiosis to produce gametes. (3) 6 4 DNA content
  4. October 2024, AS Unit 2, Q6(b)(i) (4 marks): A zygote is formed at fertilisation. Explain how an error in meiosis could result in the production of a zygote with three copies of chromosome 13. (4)
  5. October 2024, AS Unit 2, Q6(c) (1 mark): An individual can also develop Patau syndrome if part of chromosome 13 becomes attached to a different chromosome during prophase I. Suggest a reason why part o
  6. June 2024, AS Unit 2, Q7(a) (3 marks): The body cells of the mother Malayan tapir have some genetic similarities to and differences from the cells of her baby. Explain why the body cells of the mothe
  7. October 2023, AS Unit 2, Q1(b) (2 marks): Explain why it is possible for chromatid A to be genetically different from chromatid B. (2)
  8. October 2023, AS Unit 2, Q1(c) (2 marks): A student was asked to draw the four haploid cells produced by this cell in metaphase I of meiosis. The diagram shows the incomplete drawings produced by this s
  9. October 2023, AS Unit 2, Q8(c) (3 marks): An individual organism that can produce both egg cells and sperm cells is said to be a hermaphrodite. Blue dragons (Glaucus atlanticus) are sea slugs that are h
  10. June 2023, AS Unit 2, Q6(a)(i) (3 marks): Explain how meiosis causes this genetic variation. (3)
  11. June 2023, AS Unit 2, Q6(a)(ii) (2 marks): Give two differences in the arrangement of the DNA in a cell at the beginning of interphase and at the end of prophase I. (2) 1 2
  12. June 2023, AS Unit 2, Q6(b) (1 mark): The DNA content of two cells was compared. Cell A was undergoing mitosis. The mass of DNA in the cell in prophase was 12 pg. Cell B was undergoing meiosis. The
  13. June 2023, AS Unit 2, Q6(c) (6 marks): Plants can produce seeds from either cross‑fertilisation or self‑fertilisation. Self‑fertilisation occurs when male nuclei from a flower fertilises an egg cell
  14. January 2023, AS Unit 2, Q2(a)(i) (1 mark): Complete the diagram to show the number of chromosomes in the female and male gametes. (1)
  15. January 2023, AS Unit 2, Q2(a)(ii) (1 mark): Label the part of the diagram where meiosis would have occurred. (1)
  16. January 2023, AS Unit 2, Q8(a)(i) (1 mark): It was suggested that this mutant allele arose in meiosis during prophase I. Suggest how this mutant allele could be produced in prophase I. (1)
  17. October 2022, AS Unit 2, Q6(a)(i) (2 marks): The unspecialised cell is diploid. State the types of division occurring at step A and step B. (2) step A . step B
  18. June 2022, AS Unit 2, Q4(b)(ii) (3 marks): Explain how the chromosomes of an Indian muntjac egg cell could differ from those in a body cell. (3)
  19. June 2022, AS Unit 2, Q4(c) (2 marks): Chinese muntjac cells contain 23 pairs of chromosomes. The photograph shows a Chinese muntjac. (Source: © Design Pics Inc / Alamy Stock Photo) The Chinese muntj
  20. October 2021, AS Unit 2, Q7(a) (6 marks): Animals of this species are either male or hermaphrodites. Nematodes that inherit one sex chromosome are male. Nematodes that inherit two sex chromosomes are he
  21. October 2021, AS Unit 2, Q8(b)(i) (3 marks): Compare and contrast metaphase in mitosis and meiosis. (3)
  22. June 2021, AS Unit 2, Q3(b)(i) (1 mark): Name the stage of meiosis in which crossing over begins. (1)
  23. June 2021, AS Unit 2, Q3(b)(ii) (1 mark): How many of the following combinations could result from one crossover of the chromosomes shown in the diagram? • AbE • ABe • abE • abe (1) A one B two C three
  24. June 2021, AS Unit 2, Q6(b) (6 marks): Organisms have evolved different mating strategies such as: • Some male animals have sperm cells with longer middle regions, as shown in the diagram. middle reg
  25. June 2021, Unit 4, Q1(b)(iv) (1 mark): It was suggested that the chromosomes in class 2 mosses were found in pairs. Give the evidence that supports this suggestion. (1)
  26. January 2021, AS Unit 2, Q3(b) (4 marks): The photograph shows flowers from a silver trumpet tree in Thailand. (Source: © Picture/Shutterstock) Flowering plants such as the silver trumpet tree contain s
  27. October 2020, AS Unit 2, Q3(b)(ii) (2 marks): Complete the graph to show how the DNA content would change if the cell had undergone meiosis to form gametes. (2) 6 4 DNA content / a.u. 2 0 0 5 10 15 20 25 Ti
  28. October 2020, AS Unit 2, Q7(a)(i) (1 mark): In which stage of meiosis does independent assortment occur? (1) A metaphase I B metaphase II C telophase I D telophase II
  29. October 2020, AS Unit 2, Q7(a)(ii) (1 mark): In which stage of meiosis does crossing over occur? (1) A metaphase I B metaphase II C prophase I D prophase II
  30. October 2020, AS Unit 2, Q7(b) (3 marks): Genetic variation increases due to the production of new combinations of alleles. A cell has gene A and gene B with alleles A, a and B, b. Meiosis could produce
  31. January 2020, AS Unit 2, Q4(c) (3 marks): Pea plants produce flowers. Some cells in the flowers undergo meiosis. Explain how the separation of chromosomes in meiosis gives rise to genetic variation in t
  32. June 2019, AS Unit 2, Q3(a) (2 marks): Meiosis produces gametes that are genetically different. Crossing over is important to increase genetic variation. The diagram shows one pair of homologous chro

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