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Diffusion, active transport, endocytosis and exocytosis: Edexcel International A Level Biology questions

Edexcel International A Level Biology past-paper questions on 2.2.2 Diffusion, active transport, endocytosis and exocytosis, 2019–2025, with mark schemes and examiner’s reports where available.

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  3. The start of question 7

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  4. Q3(c)(i)

    October 2024 · AS Unit 3

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  6. Q3(a)

    January 2024 · AS Unit 1

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  7. Q3(b)

    January 2024 · AS Unit 1

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  8. Q3(c)

    January 2024 · AS Unit 1

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  9. Q3(d)

    January 2024 · AS Unit 1

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  10. Q3(e)

    January 2024 · AS Unit 1

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  12. The start of question 7

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  13. Q9(b)(v)

    June 2023 · AS Unit 1

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  14. Q1(b)

    June 2023 · Unit 4

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  15. Q6(a)

    June 2023 · Unit 5

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  16. Q6(b)

    June 2023 · Unit 5

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  17. Q1(b)(i)

    October 2022 · AS Unit 1

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  18. Q1(b)(ii)

    October 2022 · AS Unit 1

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  20. Q2(a)(ii)

    October 2022 · Unit 6

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All 29 questions on Diffusion, active transport, endocytosis and exocytosis, as a list
  1. June 2025, AS Unit 3, Q2(b)(iii) (1 mark): Draw an arrow next to diagram A to show the net movement of betalain during the experiment. (1)
  2. January 2025, AS Unit 1, Q6(b)(ii) (2 marks): Liver cells take up cholesterol by endocytosis. Explain how an increase in these LDL receptors will help to reduce blood cholesterol levels. (2)
  3. January 2025, AS Unit 1, Q7(d) (2 marks): The Davson and Danielli model was the first to include proteins. Explain why some membrane proteins would not be able to carry out their transport functions if
  4. October 2024, AS Unit 3, Q3(c)(i) (2 marks): Suggest two factors that may affect the rate of diffusion of the antimicrobial molecules. (2) 1 2
  5. June 2024, AS Unit 1, Q6(c)(ii) (2 marks): The absorption of glucose into the bloodstream requires membrane transport proteins. Explain why glucose cannot diffuse into the bloodstream. (2)
  6. January 2024, AS Unit 1, Q3(a) (1 mark): Which pair of membrane transport mechanisms only involves a solute moving down a concentration gradient? (1) A active transport and diffusion B active transport
  7. January 2024, AS Unit 1, Q3(b) (1 mark): Which of the following transport mechanisms involve carrier proteins in the membrane? • active transport • diffusion • exocytosis (1) A active transport only B
  8. January 2024, AS Unit 1, Q3(c) (1 mark): Which cell transport mechanism is used to take large particles or bacteria into a cell? (1) A active transport B endocytosis C exocytosis D facilitated diffusio
  9. January 2024, AS Unit 1, Q3(d) (1 mark): Which cell transport mechanism moves small lipid-soluble molecules through the membrane? (1) A active transport B diffusion C facilitated diffusion D osmosis
  10. January 2024, AS Unit 1, Q3(e) (1 mark): Channel proteins are involved in facilitated diffusion. Which row of the table describes the charge on the R groups on the amino acids of a channel protein? (1)
  11. January 2024, Unit 5, Q8(e) (2 marks): Suggest how insulin increases the uptake of glucose by muscle cells (paragraph 7). (2)
  12. October 2023, AS Unit 1, Q7(c)(i) (3 marks): Explain how the LDL‑R is involved in endocytosis of LDLs. (3)
  13. June 2023, AS Unit 1, Q9(b)(v) (2 marks): Energy is needed to maintain the concentration of ions inside the osmoconformers. Explain what this energy is being used for. (2)
  14. June 2023, Unit 4, Q1(b) (4 marks): The student suggested that magnesium ions are taken up by active transport. Explain why the student came to this conclusion. Use the information in the graph to
  15. June 2023, Unit 5, Q6(a) (3 marks): Explain how ions can cross the cell membrane. (3)
  16. June 2023, Unit 5, Q6(b) (6 marks): Ions are found within fluids in the human body in different concentrations. The graph shows the concentration of ions in intracellular fluid (cytoplasm), extrac
  17. October 2022, AS Unit 1, Q1(b)(i) (1 mark): How does a nonpolar molecule move through a cell membrane, down a concentration gradient into a cell? (1) A by active transport B by diffusion C by exocytosis D
  18. October 2022, AS Unit 1, Q1(b)(ii) (1 mark): How many of the following statements are correct for the transport of a substance by endocytosis? • transports substances out of the cell • the cell membrane su
  19. October 2022, Unit 4, Q5(c) (4 marks): Albumin binds to and activates a proton channel, hHv1. This proton channel is present in the membranes of sperm cells. When the channel is activated, sperm cell
  20. October 2022, Unit 6, Q2(a)(ii) (1 mark): Calculate the rate of diffusion per minute between 1 and 2 hours. (1) µg cm–3 min–1
  21. October 2022, Unit 6, Q2(a)(iii) (1 mark): The rate of diffusion between 4 and 5 hours is 0.40 µg cm–3 min–1. Calculate the percentage decrease in the rate of diffusion between 1 and 2 hours and between
  22. October 2022, Unit 6, Q2(a)(iv) (2 marks): Caffeine is a polar molecule. Explain the difference in the rate of diffusion between 1 and 2 hours compared with the rate of diffusion between 4 and 5 hours. (
  23. January 2022, AS Unit 1, Q6(a)(i) (1 mark): Which part would contain the statement: uses proteins? (1) A II B III C IV D VII
  24. January 2022, AS Unit 1, Q6(a)(ii) (1 mark): Which part would contain the statement: needs energy in the form of ATP? (1) A II B V C VI D VII
  25. January 2022, AS Unit 1, Q6(a)(iii) (1 mark): Which part would contain the statement: solutes can only move down a concentration gradient? (1) A II B III C V D VII
  26. June 2021, AS Unit 1, Q8(c) (6 marks): The diagram and table give information about some molecules found inside and outside a cell. Molecule Key Description small dipolar molecule consisting of two E
  27. January 2021, AS Unit 1, Q5(c)(ii) (4 marks): Explain the permeability of cell membranes to each chemical shown in the diagram. (4)
  28. October 2020, Unit 4, Q5(b)(i) (2 marks): Describe the role of channel proteins in the facilitated diffusion of lysins. (2)
  29. January 2019, AS Unit 1, Q5(b)(i) (1 mark): How does glycerol pass through the liposome membrane? (1) A active transport B diffusion C endocytosis D osmosis

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