Amino acids and polypeptides: Edexcel International A Level Biology questions
Edexcel International A Level Biology past-paper questions on 2.3.1 Amino acids and polypeptides, 2019–2025, with mark schemes and examiner’s reports where available.
Paper
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Calculations
Q1(c)
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Q1(a)(i)
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Q1(a)(ii)
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Your answerQ6(b)
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Q1(a)
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Your answerQ1(b)
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Your answerQ1(e)
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Q3(a)(i)
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Q3(a)(ii)
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Q3(a)(iii)
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Q8(h)
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Q6(a)
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Your answerQ7(a)
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Your answerQ7(b)(i)
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Q7(c)
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Q2(a)(i)
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Q2(a)(ii)
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Q5(a)(i)
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Q5(a)(ii)
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Q2(b)(i)
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Your answer
All 34 questions on Amino acids and polypeptides, as a list
- January 2025, AS Unit 1, Q1(c) (1 mark): The diagram shows parts of two amino acids. Complete the diagram to show a peptide bond joining these two amino acids. (1) R R O H N C C C H OH H H peptide bond
- January 2025, Unit 5, Q1(a)(i) (2 marks): Complete the diagram to show the molecules formed when these two amino acids join together. (2) R H R H + HO C C N H HO C C N H O H O H
- January 2025, Unit 5, Q1(a)(ii) (1 mark): Which is the type of reaction that joins these two molecules together? (1) A condensation B decarboxylation C hydrolysis D phosphorylation
- October 2024, AS Unit 1, Q6(b) (1 mark): The extent to which soybeans reduce cholesterol depends on the variety of soybeans. This reduction is influenced by two proteins found in soybeans, glycinin and
- June 2024, AS Unit 1, Q1(a) (1 mark): Enzyme molecules are formed from chains of amino acids joined together. Which pair of elements is found in all amino acids? (1) A carbon and oxygen B carbon and
- June 2024, AS Unit 1, Q1(b) (1 mark): Which row of the table describes how two amino acids are joined together in an enzyme molecule? (1) Name of bond Reaction that forms the bond A ester condensati
- June 2024, AS Unit 3, Q1(e) (4 marks): Describe a method for estimating the soluble protein concentration in the beakers in step 4. (4)
- January 2024, AS Unit 3, Q3(a)(i) (1 mark): Name a reagent that can produce a semi‑quantitative test for protein. (1)
- January 2024, AS Unit 3, Q3(a)(ii) (1 mark): State the colour change that occurs when this reagent is added to a protein solution. (1)
- January 2024, AS Unit 3, Q3(a)(iii) (1 mark): A semi‑quantitative test was used to estimate the protein concentration in a solution. A set of standards was produced using dilutions of egg white containing p
- January 2024, Unit 5, Q8(h) (3 marks): Whey and egg protein are often used to supplement protein‑poor diets. Explain why diets rich in these proteins may not be ideal for the prolonged treatment of s
- June 2023, AS Unit 1, Q6(a) (1 mark): How many of the following statements are true for proteins? • Proteins contain only the elements carbon, hydrogen and nitrogen. • Proteins can be made of more t
- October 2022, AS Unit 1, Q7(a) (1 mark): The connecting region is removed from proinsulin, leaving the A chain connected to the B chain by disulfide bridges ( S S ). Which row of the table shows the po
- October 2022, AS Unit 1, Q7(b)(i) (1 mark): What percentage of proinsulin is the connecting region? (1) Answer %
- October 2022, AS Unit 1, Q7(c) (2 marks): Suggest how insulin is synthesised from proinsulin. Use the information in the diagram to support your answer. (2)
- October 2022, AS Unit 3, Q2(a)(i) (1 mark): Name the bond between amino acids that is broken by this enzyme. (1)
- October 2022, AS Unit 3, Q2(a)(ii) (1 mark): Name the process that breaks the bond between amino acids. (1)
- October 2022, Unit 4, Q5(a)(i) (1 mark): Calculate the mean molecular mass of an amino acid in albumin. Give your answer to an appropriate number of significant figures. (1) Answer daltons
- June 2022, AS Unit 1, Q5(a)(ii) (3 marks): Keratin contains a high proportion of the amino acid, cysteine. Disulfide bridges form between the R groups of two cysteines. The diagram shows the R group of c
- January 2022, Unit 4, Q2(b)(i) (1 mark): Which row of the table describes the bonds that form between amino acids in a protein? (1) Name of bond Parts of the amino acid that the bond forms between A pe
- October 2021, AS Unit 1, Q4(a)(ii) (1 mark): Which row of the table describes how amino acids are joined together to form a protein? (1) name of bond type of reaction A ester condensation B ester hydrolysi
- October 2021, AS Unit 3, Q1(a)(i) (2 marks): Describe how you could test for protein in this filtrate. (2)
- October 2021, AS Unit 3, Q1(b)(ii) (1 mark): Some of the total nitrogen content of a food is not due to protein. Give one other type of organic molecule that contains nitrogen. (1)
- June 2021, AS Unit 1, Q1(a) (4 marks): Polymers are large molecules made of monomers. The table gives information about some of these polymers. Complete the table by filling in the empty boxes with e
- October 2020, AS Unit 1, Q1(a) (5 marks): Read through the following account of the primary structure of a protein. (5) Complete the account by writing the most appropriate word or words on the dotted l
- October 2020, Unit 4, Q3(c)(i) (1 mark): Which row of the table describes how two amino acids join together? (1) Bond formed between Type of reaction A carbon and nitrogen condensation B carbon and nit
- October 2020, Unit 4, Q3(c)(ii) (2 marks): Explain why amino acids cannot be produced from glucose alone. (2)
- June 2019, AS Unit 1, Q8(a) (1 mark): Which of the following diagrams shows the R group only of AzPhe? (1) N3 A CH2 C N3 B CH2 N3 C CH2 D C H
- June 2019, AS Unit 1, Q8(b)(i) (1 mark): Name the covalent bond that joins two amino acids in a condensation reaction. (1)
- June 2019, AS Unit 1, Q8(b)(ii) (2 marks): Draw two circles on the diagram of AzPhe to show which parts of the molecule are lost when AzPhe joins to two other amino acids by condensation reactions. (2) N
- June 2019, AS Unit 1, Q8(c)(i) (2 marks): Calculate the ratio of phenylalanine to AzPhe in this part of a modified silk molecule. (2) Answer
- January 2019, AS Unit 1, Q7(b)(i) (1 mark): The diagram shows the R group of the amino acids, alanine, aspartate and tryptophan. CH2 H C CH2 C C CH CH3 C HC C CH −O O N C H H alanine aspartate tryptophan
- January 2019, AS Unit 1, Q7(b)(ii) (2 marks): The solubility of an amino acid can be determined by measuring the maximum mass of the amino acid that dissolves in a known volume of solvent. The solubility of
- January 2019, AS Unit 1, Q7(c) (6 marks): The gall-forming insects secrete saliva into the plant tissues. The saliva contains enzymes that change the nutrients in the leaf and cause the galls to form. T
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