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Amino acids and polypeptides: Edexcel International A Level Biology questions

Edexcel International A Level Biology past-paper questions on 2.3.1 Amino acids and polypeptides, 2019–2025, with mark schemes and examiner’s reports where available.

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3,127 questions

  1. Q1(c)

    January 2025 · AS Unit 1

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  2. Q1(a)(i)

    January 2025 · Unit 5

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  3. Q1(a)(ii)

    January 2025 · Unit 5

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  4. Q6(b)

    October 2024 · AS Unit 1

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  5. Q1(a)

    June 2024 · AS Unit 1

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  6. Q1(b)

    June 2024 · AS Unit 1

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  7. The start of question 1

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  8. Q3(a)(i)

    January 2024 · AS Unit 3

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  9. Q3(a)(ii)

    January 2024 · AS Unit 3

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  10. Q3(a)(iii)

    January 2024 · AS Unit 3

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  11. Q8(h)

    January 2024 · Unit 5

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  12. Q6(a)

    June 2023 · AS Unit 1

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  13. Q7(a)

    October 2022 · AS Unit 1

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  14. Q7(b)(i)

    October 2022 · AS Unit 1

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  15. Q7(c)

    October 2022 · AS Unit 1

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  16. Q2(a)(i)

    October 2022 · AS Unit 3

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  17. Q2(a)(ii)

    October 2022 · AS Unit 3

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  18. Q5(a)(i)

    October 2022 · Unit 4

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  19. Q5(a)(ii)

    June 2022 · AS Unit 1

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  20. Q2(b)(i)

    January 2022 · Unit 4

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All 34 questions on Amino acids and polypeptides, as a list
  1. January 2025, AS Unit 1, Q1(c) (1 mark): The diagram shows parts of two amino acids. Complete the diagram to show a peptide bond joining these two amino acids. (1) R R O H N C C C H OH H H peptide bond
  2. January 2025, Unit 5, Q1(a)(i) (2 marks): Complete the diagram to show the molecules formed when these two amino acids join together. (2) R H R H + HO C C N H HO C C N H O H O H
  3. January 2025, Unit 5, Q1(a)(ii) (1 mark): Which is the type of reaction that joins these two molecules together? (1) A condensation B decarboxylation C hydrolysis D phosphorylation
  4. October 2024, AS Unit 1, Q6(b) (1 mark): The extent to which soybeans reduce cholesterol depends on the variety of soybeans. This reduction is influenced by two proteins found in soybeans, glycinin and
  5. June 2024, AS Unit 1, Q1(a) (1 mark): Enzyme molecules are formed from chains of amino acids joined together. Which pair of elements is found in all amino acids? (1) A carbon and oxygen B carbon and
  6. June 2024, AS Unit 1, Q1(b) (1 mark): Which row of the table describes how two amino acids are joined together in an enzyme molecule? (1) Name of bond Reaction that forms the bond A ester condensati
  7. June 2024, AS Unit 3, Q1(e) (4 marks): Describe a method for estimating the soluble protein concentration in the beakers in step 4. (4)
  8. January 2024, AS Unit 3, Q3(a)(i) (1 mark): Name a reagent that can produce a semi‑quantitative test for protein. (1)
  9. January 2024, AS Unit 3, Q3(a)(ii) (1 mark): State the colour change that occurs when this reagent is added to a protein solution. (1)
  10. January 2024, AS Unit 3, Q3(a)(iii) (1 mark): A semi‑quantitative test was used to estimate the protein concentration in a solution. A set of standards was produced using dilutions of egg white containing p
  11. January 2024, Unit 5, Q8(h) (3 marks): Whey and egg protein are often used to supplement protein‑poor diets. Explain why diets rich in these proteins may not be ideal for the prolonged treatment of s
  12. June 2023, AS Unit 1, Q6(a) (1 mark): How many of the following statements are true for proteins? • Proteins contain only the elements carbon, hydrogen and nitrogen. • Proteins can be made of more t
  13. October 2022, AS Unit 1, Q7(a) (1 mark): The connecting region is removed from proinsulin, leaving the A chain connected to the B chain by disulfide bridges ( S S ). Which row of the table shows the po
  14. October 2022, AS Unit 1, Q7(b)(i) (1 mark): What percentage of proinsulin is the connecting region? (1) Answer %
  15. October 2022, AS Unit 1, Q7(c) (2 marks): Suggest how insulin is synthesised from proinsulin. Use the information in the diagram to support your answer. (2)
  16. October 2022, AS Unit 3, Q2(a)(i) (1 mark): Name the bond between amino acids that is broken by this enzyme. (1)
  17. October 2022, AS Unit 3, Q2(a)(ii) (1 mark): Name the process that breaks the bond between amino acids. (1)
  18. October 2022, Unit 4, Q5(a)(i) (1 mark): Calculate the mean molecular mass of an amino acid in albumin. Give your answer to an appropriate number of significant figures. (1) Answer daltons
  19. June 2022, AS Unit 1, Q5(a)(ii) (3 marks): Keratin contains a high proportion of the amino acid, cysteine. Disulfide bridges form between the R groups of two cysteines. The diagram shows the R group of c
  20. January 2022, Unit 4, Q2(b)(i) (1 mark): Which row of the table describes the bonds that form between amino acids in a protein? (1) Name of bond Parts of the amino acid that the bond forms between A pe
  21. October 2021, AS Unit 1, Q4(a)(ii) (1 mark): Which row of the table describes how amino acids are joined together to form a protein? (1) name of bond type of reaction A ester condensation B ester hydrolysi
  22. October 2021, AS Unit 3, Q1(a)(i) (2 marks): Describe how you could test for protein in this filtrate. (2)
  23. October 2021, AS Unit 3, Q1(b)(ii) (1 mark): Some of the total nitrogen content of a food is not due to protein. Give one other type of organic molecule that contains nitrogen. (1)
  24. June 2021, AS Unit 1, Q1(a) (4 marks): Polymers are large molecules made of monomers. The table gives information about some of these polymers. Complete the table by filling in the empty boxes with e
  25. October 2020, AS Unit 1, Q1(a) (5 marks): Read through the following account of the primary structure of a protein. (5) Complete the account by writing the most appropriate word or words on the dotted l
  26. October 2020, Unit 4, Q3(c)(i) (1 mark): Which row of the table describes how two amino acids join together? (1) Bond formed between Type of reaction A carbon and nitrogen condensation B carbon and nit
  27. October 2020, Unit 4, Q3(c)(ii) (2 marks): Explain why amino acids cannot be produced from glucose alone. (2)
  28. June 2019, AS Unit 1, Q8(a) (1 mark): Which of the following diagrams shows the R group only of AzPhe? (1) N3 A CH2 C N3 B CH2 N3 C CH2 D C H
  29. June 2019, AS Unit 1, Q8(b)(i) (1 mark): Name the covalent bond that joins two amino acids in a condensation reaction. (1)
  30. June 2019, AS Unit 1, Q8(b)(ii) (2 marks): Draw two circles on the diagram of AzPhe to show which parts of the molecule are lost when AzPhe joins to two other amino acids by condensation reactions. (2) N
  31. June 2019, AS Unit 1, Q8(c)(i) (2 marks): Calculate the ratio of phenylalanine to AzPhe in this part of a modified silk molecule. (2) Answer
  32. January 2019, AS Unit 1, Q7(b)(i) (1 mark): The diagram shows the R group of the amino acids, alanine, aspartate and tryptophan. CH2 H C CH2 C C CH CH3 C HC C CH −O O N C H H alanine aspartate tryptophan
  33. January 2019, AS Unit 1, Q7(b)(ii) (2 marks): The solubility of an amino acid can be determined by measuring the maximum mass of the amino acid that dissolves in a known volume of solvent. The solubility of
  34. January 2019, AS Unit 1, Q7(c) (6 marks): The gall-forming insects secrete saliva into the plant tissues. The saliva contains enzymes that change the nutrients in the leaf and cause the galls to form. T

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