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Chromatography: Edexcel A‑Level Chemistry questions

Every Edexcel A-Level Chemistry exam question on 19C Chromatography, 2016–2025, with its mark scheme and examiner’s report.

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2,028 questions

  1. Q6(a)

    June 2023 · Paper 3

    1 mark19C Chromatography
    The whole paper ↗
    June 2023 Paper 3, question 6(a): State how chromatography separates the components of a mixture. (1)

  2. Q6(b)(ii)

    June 2023 · Paper 3

    3 marks19C Chromatography
    The whole paper ↗
    June 2023 Paper 3, question 6(b)(ii): Some amino acid mixtures cannot be effectively separated in one chromatography ‘run’. The chromatography paper from the first run is dried but not developed. Th

  3. Q6(b)(iii)

    June 2023 · Paper 3

    1 mark19C Chromatography
    The whole paper ↗
    June 2023 Paper 3, question 6(b)(iii): Name a reagent that locates colourless amino acids by producing a coloured compound. (1)

  4. Q6(c)

    June 2023 · Paper 3

    1 mark19C Chromatography
    The whole paper ↗
    June 2023 Paper 3, question 6(c): State the technique that is used in conjunction with gas chromatography (GC) when carrying out forensic testing. (1)

  5. Q3(a)(i)

    June 2018 · Paper 2

    1 mark19C Chromatography
    The whole paper ↗
    June 2018 Paper 2, question 3(a)(i): Calculate the Rf value for the amino acid lysine. Give your answer to an appropriate number of significant figures. (1)

  6. Q3(a)(ii)

    June 2018 · Paper 2

    3 marks19C Chromatography
    The whole paper ↗
    June 2018 Paper 2, question 3(a)(ii): Identify by name the two amino acids present in the tripeptide, giving a reason for the lack of a third spot. (3)

  7. Q3(a)(iii)

    June 2018 · Paper 2

    2 marks19C Chromatography
    The whole paper ↗
    June 2018 Paper 2, question 3(a)(iii): Give two reasons why different amino acids have different Rf values. (2)

  8. Q3(a)(iv)

    June 2018 · Paper 2

    1 mark19C Chromatography
    The whole paper ↗
    June 2018 Paper 2, question 3(a)(iv): In chromatography, a ‘locating’ reagent is often used when the components in a mixture are colourless. Which reagent is used to locate the amino acid spots? (1)

  9. Q3(b)(i)

    June 2018 · Paper 2

    1 mark19C Chromatography
    The whole paper ↗
    June 2018 Paper 2, question 3(b)(i): State why argon and nitrogen are suitable carrier gases for gas chromatography. (1)

  10. Q3(b)(ii)

    June 2018 · Paper 2

    3 marks19C Chromatography
    The whole paper ↗
    June 2018 Paper 2, question 3(b)(ii): A mixture containing one part substance X, two parts substance Y and one part substance Z was separated by gas chromatography. Substance X has a retention time

  11. Q3(d)

    June 2017 · Paper 3

    2 marks19C Chromatography18B Amines, amides, amino acids and proteins
    The whole paper ↗
    June 2017 Paper 3, question 3(d): The dipeptide formed in part (c) is hydrolysed under acidic conditions and the resulting mixture is analysed by column chromatography. The column uses a polar s
All 11 questions on Chromatography, as a list
  1. June 2023, Paper 3, Q6(a) (1 mark): State how chromatography separates the components of a mixture. (1)
  2. June 2023, Paper 3, Q6(b)(ii) (3 marks): Some amino acid mixtures cannot be effectively separated in one chromatography ‘run’. The chromatography paper from the first run is dried but not developed. Th
  3. June 2023, Paper 3, Q6(b)(iii) (1 mark): Name a reagent that locates colourless amino acids by producing a coloured compound. (1)
  4. June 2023, Paper 3, Q6(c) (1 mark): State the technique that is used in conjunction with gas chromatography (GC) when carrying out forensic testing. (1)
  5. June 2018, Paper 2, Q3(a)(i) (1 mark): Calculate the Rf value for the amino acid lysine. Give your answer to an appropriate number of significant figures. (1)
  6. June 2018, Paper 2, Q3(a)(ii) (3 marks): Identify by name the two amino acids present in the tripeptide, giving a reason for the lack of a third spot. (3)
  7. June 2018, Paper 2, Q3(a)(iii) (2 marks): Give two reasons why different amino acids have different Rf values. (2)
  8. June 2018, Paper 2, Q3(a)(iv) (1 mark): In chromatography, a ‘locating’ reagent is often used when the components in a mixture are colourless. Which reagent is used to locate the amino acid spots? (1)
  9. June 2018, Paper 2, Q3(b)(i) (1 mark): State why argon and nitrogen are suitable carrier gases for gas chromatography. (1)
  10. June 2018, Paper 2, Q3(b)(ii) (3 marks): A mixture containing one part substance X, two parts substance Y and one part substance Z was separated by gas chromatography. Substance X has a retention time
  11. June 2017, Paper 3, Q3(d) (2 marks): The dipeptide formed in part (c) is hydrolysed under acidic conditions and the resulting mixture is analysed by column chromatography. The column uses a polar s

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