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Genetic screening: Edexcel A‑Level Biology A questions

Every Edexcel A-Level Biology A exam question on Genetic screening (specification points 2.15–2.16), 2016–2025, with its mark scheme and examiner’s report.

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1,749 questions

  1. Q3(c)

    June 2024 · Paper 2

    The whole paper ↗
    June 2024 Paper 2, question 3(c): Radiation has leaked from accidents at other nuclear power stations. This has led to mutations in the developing embryos of pregnant women. Prenatal genetic scr
  2. Q4(a)

    June 2023 · Paper 2

    The whole paper ↗
    June 2023 Paper 2, question 4(a): Compare and contrast the use of pre-implantation genetic diagnosis (PGD) and amniocentesis. (4)
  3. Q4(b)

    June 2023 · Paper 2

    The whole paper ↗
    June 2023 Paper 2, question 4(b): Describe two different social issues related to the use of PGD. (2)
  4. Q4(b)(ii)

    June 2023 · AS Paper 1

    The whole paper ↗
    June 2023 AS Paper 1, question 4(b)(ii): An embryo, created by IVF, can be screened for Tay‑Sachs disease before being placed in the mother’s uterus. Name this type of genetic screening. (1)
  5. Q4(b)(iii)

    June 2023 · AS Paper 1

    The whole paper ↗
    June 2023 AS Paper 1, question 4(b)(iii): Explain why the mother may prefer this type of prenatal screening to amniocentesis. (2)
  6. Q5(c)(iii)

    June 2022 · AS Paper 1

    The whole paper ↗
    June 2022 AS Paper 1, question 5(c)(iii): Individual 12 is pregnant. She has been advised to have a genetic screening test for cystic fibrosis. Give the name of the prenatal genetic screening test that
  7. Q5(c)(iv)

    June 2022 · AS Paper 1

    The whole paper ↗
    June 2022 AS Paper 1, question 5(c)(iv): Discuss the ethical issues relating to the use of genetic screening during pregnancy. (3)
  8. Q5(b)(ii)

    October 2020 · AS Paper 1

    The whole paper ↗
    October 2020 AS Paper 1, question 5(b)(ii): Individual 12 is pregnant and wants to know if her baby has alkaptonuria. State and justify a suitable method of collecting cells for prenatal testing. (3)
  9. Q11(c)

    June 2019 · Paper 1

    The whole paper ↗
    June 2019 Paper 1, question 11(c): Genetic testing can be used to identify individuals who have genetic disorders such as Batten disease. The table shows examples of some types of genetic screeni
  10. Q4(b)(iii)

    June 2018 · AS Paper 1

    The whole paper ↗
    June 2018 AS Paper 1, question 4(b)(iii): An embryo, created by IVF, can be screened before it is placed in the mother’s uterus. Name this type of genetic screening. (1)
  11. Q4(b)(iv)

    June 2018 · AS Paper 1

    The whole paper ↗
    June 2018 AS Paper 1, question 4(b)(iv): Explain one ethical issue relating to the use of prenatal genetic screening. (2)
  12. Q1(b)

    June 2016 · AS Paper 1

    The whole paper ↗
    June 2016 AS Paper 1, question 1(b): Tay‑Sachs disease can be detected during pregnancy. Name the prenatal test that could be used to detect Tay‑Sachs disease at 11 weeks of pregnancy. (1)
  13. Q1(c)

    June 2016 · AS Paper 1

    The whole paper ↗
    June 2016 AS Paper 1, question 1(c): Explain why this couple may choose not to have this test. (3)
All 13 questions on Genetic screening, as a list
  1. June 2024, Paper 2, Q3(c) (1 mark): Radiation has leaked from accidents at other nuclear power stations. This has led to mutations in the developing embryos of pregnant women. Prenatal genetic scr
  2. June 2023, Paper 2, Q4(a) (4 marks): Compare and contrast the use of pre-implantation genetic diagnosis (PGD) and amniocentesis. (4)
  3. June 2023, Paper 2, Q4(b) (2 marks): Describe two different social issues related to the use of PGD. (2)
  4. June 2023, AS Paper 1, Q4(b)(ii) (1 mark): An embryo, created by IVF, can be screened for Tay‑Sachs disease before being placed in the mother’s uterus. Name this type of genetic screening. (1)
  5. June 2023, AS Paper 1, Q4(b)(iii) (2 marks): Explain why the mother may prefer this type of prenatal screening to amniocentesis. (2)
  6. June 2022, AS Paper 1, Q5(c)(iii) (1 mark): Individual 12 is pregnant. She has been advised to have a genetic screening test for cystic fibrosis. Give the name of the prenatal genetic screening test that
  7. June 2022, AS Paper 1, Q5(c)(iv) (3 marks): Discuss the ethical issues relating to the use of genetic screening during pregnancy. (3)
  8. October 2020, AS Paper 1, Q5(b)(ii) (3 marks): Individual 12 is pregnant and wants to know if her baby has alkaptonuria. State and justify a suitable method of collecting cells for prenatal testing. (3)
  9. June 2019, Paper 1, Q11(c) (6 marks): Genetic testing can be used to identify individuals who have genetic disorders such as Batten disease. The table shows examples of some types of genetic screeni
  10. June 2018, AS Paper 1, Q4(b)(iii) (1 mark): An embryo, created by IVF, can be screened before it is placed in the mother’s uterus. Name this type of genetic screening. (1)
  11. June 2018, AS Paper 1, Q4(b)(iv) (2 marks): Explain one ethical issue relating to the use of prenatal genetic screening. (2)
  12. June 2016, AS Paper 1, Q1(b) (1 mark): Tay‑Sachs disease can be detected during pregnancy. Name the prenatal test that could be used to detect Tay‑Sachs disease at 11 weeks of pregnancy. (1)
  13. June 2016, AS Paper 1, Q1(c) (3 marks): Explain why this couple may choose not to have this test. (3)

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