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Amino acids and amides: OCR A‑Level Chemistry A questions

OCR A-Level Chemistry A past-paper questions on 6.2.2.1 Amino acids and amides, 2016–2025, with mark schemes and examiner’s reports where available.

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  1. Q22(a)(ii)

    June 2025 · Paper 2

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    The start of question 22

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  2. Q22(b)(ii)

    June 2025 · Paper 2

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  3. Q9

    June 2024 · Paper 2

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  4. Q21(b)(i)

    June 2023 · Paper 2

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  6. Q18(d)(i)

    November 2021 · Paper 2

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  7. Q1(c)

    November 2020 · Paper 3

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  8. Q17(a)(i)

    June 2019 · Paper 2

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  9. Q2

    June 2018 · Paper 2

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  10. Q17(b)

    June 2018 · Paper 2

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All 10 questions on Amino acids and amides, as a list
  1. June 2025, Paper 2, Q22(a)(ii) (2 marks): Compound S has two possible structures. Draw both of these structures. [2] Question 22(b) starts on Page 30
  2. June 2025, Paper 2, Q22(b)(ii) (1 mark): α-Amino acids have the NH2 group bonded to the carbon atom adjacent to the carboxylic acid group. Suggest the difference between an α-keto acid and a β-keto aci
  3. June 2024, Paper 2, Q9 (1 mark): Which compound is a secondary amide? N A OH O N C H B O O C N H OH NH2 C HO D O Your answer [1]
  4. June 2023, Paper 2, Q21(b)(i) (1 mark): What is the systematic name of valine? [1]
  5. June 2023, Paper 2, Q21(c)(ii) (4 marks): A student hydrolyses compound E with dilute hydrochloric acid, HCl (aq). Draw the structures of the organic products formed by this hydrolysis. [4]
  6. November 2021, Paper 2, Q18(d)(i) (2 marks): Suggest the structure of each ion in this lysine salt of ibuprofen, including the position of any charges. – ion + ion [2]
  7. November 2020, Paper 3, Q1(c) (2 marks): The amino acid Z−H2NCH=CHCOOH can react to form a cyclic compound with the molecular formula C3H3NO and one other product. Complete the equation for this reacti
  8. June 2019, Paper 2, Q17(a)(i) (4 marks): In the boxes, draw the organic products for the reactions of serine shown below. (CH3)2CHOH / H2SO4 H+(aq) H O excess CH3COCl C C H2N OH CH2 OH serine [4]
  9. June 2018, Paper 2, Q2 (1 mark): Which compound is a secondary amide? O CH3 A HO C CH2 N H O CH3 B HO C CH2 N CH3 O CH3 C H3C C N H O CH3 D H3C C N CH3 Your answer [1]
  10. June 2018, Paper 2, Q17(b) (2 marks): The α-amino acid lysine (R = (CH2)4NH2) reacts with an excess of dilute hydrochloric acid to form a salt. Draw the structure of the salt formed in this reaction

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