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Stem cells: OCR A‑Level Biology A questions

OCR A-Level Biology A past-paper questions on 2.1.6.5 Stem cells, 2016–2025, with mark schemes and examiner’s reports where available.

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1,983 questions

  1. Q16(b)(i)

    June 2025 · Paper 2

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  2. Q16(b)(ii)

    June 2025 · Paper 2

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  3. Q7(b)(i)

    June 2025 · Paper 3

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  4. Q3

    June 2025 · AS Paper 1

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  5. Q26(a)

    June 2025 · AS Paper 1

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  6. Q26(c)

    June 2025 · AS Paper 1

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  7. Q3(a)

    June 2024 · Paper 3

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  8. Q5(f)(i)

    June 2024 · Paper 3

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  9. Q2

    June 2023 · Paper 2

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  10. Q19

    June 2023 · AS Paper 1

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  11. Q5(b)(iii)

    June 2023 · AS Paper 2

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  12. Q5(c)

    June 2023 · AS Paper 2

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  13. Q21(d)(i)

    June 2022 · Paper 1

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  14. Q21(d)(ii)

    June 2022 · Paper 1

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  15. Q21(d)(iii)

    June 2022 · Paper 1

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  16. Q25(b)(i)

    June 2022 · AS Paper 1

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  17. Q25(c)

    June 2022 · AS Paper 1

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  18. Q25(d)

    June 2022 · AS Paper 1

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  19. Q20(d)

    November 2021 · Paper 1

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  20. Q3

    November 2020 · Paper 2

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All 33 questions on Stem cells, as a list
  1. June 2025, Paper 2, Q16(b)(i) (2 marks): State two features of stem cells, not visible under the microscope, that distinguish them from specialised cells. 1 2 [2]
  2. June 2025, Paper 2, Q16(b)(ii) (2 marks): Stem cells have a number of uses in medicine. Explain why stem cells are useful tools in medical research. [2]
  3. June 2025, Paper 3, Q7(b)(i) (1 mark): State the location of the stem cells that differentiate into neutrophils. [1]
  4. June 2025, AS Paper 1, Q3 (1 mark): Which type of stem cell can become specialised into more than one cell type but is limited to a range of cell types? A Embryonic B Multipotent C Pluripotent D T
  5. June 2025, AS Paper 1, Q26(a) (2 marks): Bone marrow contains stem cells which can only differentiate into blood cell types including erythrocytes and neutrophils. Complete the table to show which stat
  6. June 2025, AS Paper 1, Q26(c) (1 mark): One area of potential use for stem cells is in medicine, for example, to repair damaged tissues and to treat neurological conditions. State one other potential
  7. June 2024, Paper 3, Q3(a) (2 marks): The sentences describe the role of meristems in producing xylem vessels. Complete the sentences using the most appropriate words or phrases. Meristem cells are
  8. June 2024, Paper 3, Q5(f)(i) (1 mark): State a feature of stem cells that allows them to be used to produce pancreatic β-cells. [1]
  9. June 2023, Paper 2, Q2 (1 mark): Bone marrow stem cells are a source of erythrocytes. Which statement about bone marrow stem cells and their role in the production of erythrocytes is correct? A
  10. June 2023, AS Paper 1, Q19 (1 mark): Which statement is true of stem cells? A All stem cells can naturally divide to produce a new organism. B Stem cells are differentiated and specialised cells. C
  11. June 2023, AS Paper 2, Q5(b)(iii) (1 mark): Neutrophils are produced by stem cells. State where in the body these stem cells are found. [1]
  12. June 2023, AS Paper 2, Q5(c) (2 marks): Parkinson’s disease is a neurological condition which results in problems with co-ordination of body movements. • It can be caused by the death of dopamine prod
  13. June 2022, Paper 1, Q21(d)(i) (2 marks): The ESCs are described as pluripotent. Explain what is meant by pluripotent. [2]
  14. June 2022, Paper 1, Q21(d)(ii) (3 marks): The scientists concluded that growing the ESCs with growth factors caused them to differentiate into functional thyroid tissue. Evaluate this conclusion. [3]
  15. June 2022, Paper 1, Q21(d)(iii) (2 marks): The scientists then repeated their experiments with adult stem cells taken from the skin of patients with hypothyroidism. These cells were artificially transfor
  16. June 2022, AS Paper 1, Q25(b)(i) (2 marks): On the photomicrograph, label the location of meristem tissue. [2]
  17. June 2022, AS Paper 1, Q25(c) (2 marks): Explain the role of meristem tissue in a stem. [2]
  18. June 2022, AS Paper 1, Q25(d) (1 mark): Name one potential use of stem cells in medicine. [1]
  19. November 2021, Paper 1, Q20(d) (2 marks): Plant growth requires the production of new xylem cells. Describe how new xylem cells are produced. [2]
  20. November 2020, Paper 2, Q3 (1 mark): Which of the following statements, A to D, is not true of human erythrocytes? A They are produced from stem cells. B They are produced in bone marrow. C They ar
  21. November 2020, Paper 2, Q12 (1 mark): Which of the following, A to D, is not true about adult stem cells? A They are found in bone marrow. B They are not specialised. C They are totipotent. D They c
  22. November 2020, AS Paper 1, Q21(b)(i) (2 marks): Explain the role of embryonic stem cells in the development of the embryo. [2]
  23. November 2020, AS Paper 1, Q21(b)(ii) (2 marks): Explain why the cells of the inner cell mass are not totipotent stem cells. [2]
  24. November 2020, AS Paper 2, Q1(c)(i) (3 marks): A student wrote the following passage about cells: ƇErythrocytes and neutrophils are formed in the spleen. One of the places ciliated epithelial cells are found
  25. November 2020, AS Paper 2, Q1(c)(ii) (2 marks): A man with a body mass of 73 kg was admitted to hospital with an infection. His neutrophil production was measured at approximately 3804 billion cells in a 24h
  26. June 2019, Paper 1, Q1 (1 mark): Rheumatoid arthritis is a long-term condition that causes pain, swelling and stiffness in the joints. Which of the following, A to D, explains why stem cells ar
  27. June 2019, Paper 1, Q5 (1 mark): Both of the cell types P and Q develop from haematopoetic stem cells in the bone marrow. Which of the following statements, A to D, correctly describes haematop
  28. June 2019, Paper 1, Q6 (1 mark): Which of the following statements, A to D, correctly explains why meristems can differentiate into xylem vessels in plant stems? A Meristems are living and unsp
  29. June 2019, AS Paper 2, Q2(b)(i) (1 mark): Name the cell labelled B. [1]
  30. June 2018, AS Paper 1, Q23(c) (1 mark): The tissues labelled Q and S in Fig. 23 are produced by mitosis from the tissue labelled R on Fig. 23. Identify the tissue labelled R. R [1]
  31. June 2017, Paper 1, Q22(c)(i) (3 marks): Explain why podocytes are usually unable to undergo mitosis. [3]
  32. June 2017, Paper 1, Q22(c)(ii) (2 marks): Studies show that after damage by infection or injury, it is possible for nephron tissues to be regenerated. Adult stem cells are involved in this process. What
  33. June 2017, AS Paper 2, Q1(c) (4 marks): The use of stem cells is being evaluated for the treatment of certain human diseases. Name two potential sources of human stem cells and for one source, describ

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