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Membrane structure and permeability: OCR A‑Level Biology A questions

OCR A-Level Biology A past-paper questions on 2.1.5.2 Membrane structure and permeability, 2016–2025, with mark schemes and examiner’s reports where available.

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1,983 questions

  1. Q24(b)(i)

    June 2025 · AS Paper 1

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  2. Q24(b)(ii)

    June 2025 · AS Paper 1

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  3. Q24(b)(iii)

    June 2025 · AS Paper 1

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  4. Q2(c)

    June 2025 · AS Paper 2

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  5. Q21(c)(ii)

    June 2024 · Paper 1

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  6. Q21(c)(iii)

    June 2024 · Paper 1

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  7. Q22(a)

    June 2024 · Paper 1

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    The start of question 22

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  8. Q22(b)(i)

    June 2024 · Paper 1

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    The start of question 22

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  9. Q22(b)(ii)

    June 2024 · Paper 1

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  10. Q14

    June 2023 · Paper 1

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  11. Q15

    June 2023 · Paper 1

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  12. Q25(b)

    June 2023 · AS Paper 1

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  13. Q1(a)

    June 2022 · AS Paper 2

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  14. Q1(b)

    June 2022 · AS Paper 2

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  15. Q1(c)(i)

    June 2022 · AS Paper 2

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  16. Q1(c)(ii)

    June 2022 · AS Paper 2

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  17. Q1(d)

    June 2022 · AS Paper 2

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  18. Q18(b)(i)

    November 2021 · Paper 2

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  19. Q18(b)(ii)

    November 2021 · Paper 2

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  20. Q18(b)(iii)

    November 2021 · Paper 2

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All 34 questions on Membrane structure and permeability, as a list
  1. June 2025, AS Paper 1, Q24(b)(i) (2 marks): State two variables that were not controlled in this experiment. 1 2 [2]
  2. June 2025, AS Paper 1, Q24(b)(ii) (1 mark): One of the students suggests using a red filter in the colorimeter because this is what they had used for a Benedict’s test. Suggest why the student is incorrec
  3. June 2025, AS Paper 1, Q24(b)(iii) (3 marks): Explain how the students can process their data to assess repeatability. [3]
  4. June 2025, AS Paper 2, Q2(c) (3 marks): Using your knowledge of the phospholipid bilayer in plasma membranes, explain how an increase in temperature affects the permeability of the membrane. [3]
  5. June 2024, Paper 1, Q21(c)(ii) (3 marks): Scientists investigate the effect of hydrogen peroxide on sperm cells. This is the method that they use: • incubate sperm cells with different concentrations of
  6. June 2024, Paper 1, Q21(c)(iii) (2 marks): Suggest how hydrogen peroxide could affect the plasma membrane. [2]
  7. June 2024, Paper 1, Q22(a) (2 marks): The student controls the mass of beetroot in this investigation. Identify two other variables that the student should control in this investigation. 1 2 [2]
  8. June 2024, Paper 1, Q22(b)(i) (2 marks): Explain the shape of the graph. [2]
  9. June 2024, Paper 1, Q22(b)(ii) (2 marks): The student repeats the experiment at a temperature of 30 °C. Sketch the graph you expect the student to obtain. [2] Answer on the graph.
  10. June 2023, Paper 1, Q14 (1 mark): One student made the following observations: 1 Ethanol disrupts the cell membranes leading to increased permeability. 2 The permeability of the cell membranes i
  11. June 2023, Paper 1, Q15 (1 mark): The students were asked to decide whether the permeability of the membrane is significantly greater with 50% ethanol compared to 40% ethanol. Which statistical
  12. June 2023, AS Paper 1, Q25(b) (3 marks): The presence of cholesterol is one of several factors that affect membrane fluidity. A student examined two different cell surface membranes. One membrane had a
  13. June 2022, AS Paper 2, Q1(a) (4 marks): A second group of students made improvements to this method. One of the improvements they made was to carry out two further trials at each temperature. Suggest
  14. June 2022, AS Paper 2, Q1(b) (1 mark): Name the independent variable in this investigation. [1]
  15. June 2022, AS Paper 2, Q1(c)(i) (3 marks): The table shows the results obtained by the second group of students. Absorbance (%) Temperature (°C) Trial 1 Trial 2 Trial 3 Mean 10 0 0 0 0.0 20 0 0 0 0.0 30
  16. June 2022, AS Paper 2, Q1(c)(ii) (6 marks): The cells in beetroot contain a red pigment called betalain. The plasma membrane of the beetroot cell is impermeable to betalain. A group of students set out to
  17. June 2022, AS Paper 2, Q1(d) (2 marks): In a second experiment, students followed the same method but used pieces of beetroot that had been frozen for several days and then defrosted. They were surpri
  18. November 2021, Paper 2, Q18(b)(i) (4 marks): Present the students’ results in an appropriate table in the space below. [4]
  19. November 2021, Paper 2, Q18(b)(ii) (2 marks): The students concluded that the red pigment began to leak out of the beetroot cells at any pH below pH6. Suggest and explain why a low pH might cause the red pi
  20. November 2021, Paper 2, Q18(b)(iii) (2 marks): Outline how the students could modify their investigation to get a more accurate value for the pH at which the red pigment begins to leak out of the beetroot ce
  21. November 2021, AS Paper 1, Q19 (1 mark): The graph below shows readings from a colorimeter as pigment leaks out of beetroot membranes at different temperatures. P Absorbance (arbitrary units) Temperatu
  22. November 2020, AS Paper 1, Q3 (1 mark): Which of the lines, A to D, in the graph below, represents the effect of increasing ethanol concentration on the permeability of the plasma membrane to sodium i
  23. June 2019, AS Paper 1, Q21(a) (3 marks): In the space below, present the student’s results in an appropriate format. [3]
  24. June 2019, AS Paper 1, Q21(b)(i) (2 marks): Explain how the treatment results in the difference in the final lengths of rod A and rod E. [2]
  25. June 2019, AS Paper 1, Q21(b)(ii) (2 marks): Explain how the treatment results in the difference in the final lengths of rod D and rod F. [2]
  26. June 2019, AS Paper 1, Q21(c) (1 mark): State how the student could reduce the uncertainty of their data. [1]
  27. June 2018, Paper 1, Q20(a)(i) (3 marks): Each step in the student’s method relies on certain assumptions. For each assumption listed below, select the numbered step from the student’s method that relie
  28. June 2018, Paper 1, Q20(a)(ii) (2 marks): The student kept the ethanol solutions at a constant temperature. State two other variables which need to be controlled in this investigation to ensure the data
  29. June 2018, Paper 1, Q20(b)(i) (3 marks): Make three criticisms of the way the student has displayed these results. 1 2 3 [3]
  30. June 2018, Paper 1, Q20(b)(ii) (2 marks): Explain how carrying out replicates would improve this investigation. [2]
  31. June 2018, AS Paper 1, Q17 (1 mark): Swiss chard is a leafy green vegetable related to spinach. Some varieties have yellow stalks that have vacuoles containing yellow betaxanthin pigments. The grap
  32. June 2017, AS Paper 1, Q23(d)(i) (3 marks): Using the Student’s t-test formula below, calculate the value of t between the data for 50 °C and 60 °C. x x - A B where: x is the mean t = 2 2 S is the standar
  33. June 2017, AS Paper 1, Q23(d)(ii) (2 marks): The critical value for t at the significance level of 5%, with 18 degrees of freedom, is 2.10. Use the value of t that you calculated in part (i) to explain whe
  34. June 2017, AS Paper 1, Q23(e) (3 marks): The students plotted the data onto a graph, shown in Fig. 23. The effect of temperature on beetroot membrane permeability 0.50 0.45 0.40 0.35 0.30 absorbance 0.

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