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Endocrine communication and the adrenal glands: OCR A‑Level Biology A questions

OCR A-Level Biology A past-paper questions on 5.1.4.1 Endocrine communication and the adrenal glands, 2016–2025, with mark schemes and examiner’s reports where available.

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  4. Q21(a)(i)

    June 2022 · Paper 1

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  5. Q21(a)(ii)

    June 2022 · Paper 1

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  6. Q21(b)

    June 2022 · Paper 1

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  7. Q21(c)(i)

    June 2022 · Paper 1

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  8. Q21(c)(ii)

    June 2022 · Paper 1

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  11. Q16(b)(iv)

    November 2021 · Paper 1

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  14. Q21(a)(i)

    June 2019 · Paper 1

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  15. Q21(a)(ii)

    June 2019 · Paper 1

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  16. Q10

    June 2017 · Paper 1

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All 16 questions on Endocrine communication and the adrenal glands, as a list
  1. June 2025, Paper 1, Q5 (1 mark): Which option describes endocrine communication? A Endocrine glands release hormones into ducts such as the pancreatic duct. B Hormones are all lipid soluble and
  2. June 2025, Paper 1, Q6 (1 mark): Which option describes a role of the adrenal glands within the endocrine system? A Adrenaline is produced by the adrenal cortex. B Glucocorticoids help to regul
  3. June 2025, Paper 3, Q2(a)(ii) (2 marks): Suggest how the binding of beta blockers to adrenaline receptors prevents the conversion of ATP to cAMP. [2]
  4. June 2022, Paper 1, Q21(a)(i) (2 marks): Describe what is meant by an endocrine gland. [2]
  5. June 2022, Paper 1, Q21(a)(ii) (1 mark): The pancreas contains endocrine glands such as the Islets of Langerhans. It also contains cells that produce digestive enzymes. Suggest why the cells that produ
  6. June 2022, Paper 1, Q21(b) (2 marks): Hormones can be classed as either steroid or non-steroid. Steroids are lipid soluble. Suggest the location of the receptors for steroid hormones and state a rea
  7. June 2022, Paper 1, Q21(c)(i) (2 marks): Explain the symptoms of adrenal failure. [2]
  8. June 2022, Paper 1, Q21(c)(ii) (3 marks): Explain why patients with a pituitary tumour have adrenal failure but still respond normally to situations of danger or excitement. [3]
  9. June 2022, Paper 3, Q1(d)(i) (2 marks): Suggest how using gene therapy to increase levels of the AC6 gene in heart cells may improve heart function. [2]
  10. November 2021, Paper 1, Q16(b)(iii) (2 marks): Injury to the parts of the brain labelled G and H in Fig. 16.2 can lead to a range of symptoms including: • fatigue • weight gain • menstrual irregularities • l
  11. November 2021, Paper 1, Q16(b)(iv) (1 mark): Suggest why it can be difficult for a doctor to conclude that the symptoms described in part (iii) are definitely caused by damage to parts of the brain. [1]
  12. June 2019, Paper 1, Q15 (1 mark): The hormone aldosterone is produced by the adrenal cortex. Excess production of aldosterone can result in high blood pressure. The following statements describe
  13. June 2019, Paper 1, Q18(b) (2 marks): Acetylcholine (ACh) is a neurotransmitter in mammals. Studies have suggested that it also functions as a hormone in some invertebrate species, such as squid. Wh
  14. June 2019, Paper 1, Q21(a)(i) (2 marks): The table below describes the functions of some hormones produced by different regions of the adrenal gland. Complete the table using Fig. 21.1 and your own kno
  15. June 2019, Paper 1, Q21(a)(ii) (1 mark): Using Fig. 21.1, identify the letter and name of the region of the adrenal gland that secretes adrenaline. [1]
  16. June 2017, Paper 1, Q10 (1 mark): The hormone ecdysone is synthesised in the prothoracic glands found in the upper thorax of some invertebrates and is released into haemolymph. It is then transp

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