Skip to content
Android waitlistTry on iPad
Get started

Blood vessels and tissue fluid: OCR A‑Level Biology A questions

OCR A-Level Biology A past-paper questions on 3.1.2.2 Blood vessels and tissue fluid, 2016–2025, with mark schemes and examiner’s reports where available.

Paper
All papers
Exam
All years
Calculations

1,983 questions

  1. Q20(a)

    June 2025 · Paper 1

    The whole paper ↗

    Loading the question…

    Open the full PDF
  2. Q20(b)

    June 2025 · Paper 1

    The whole paper ↗

    Loading the question…

    Open the full PDF
  3. Q6

    June 2024 · Paper 1

    The whole paper ↗

    Loading the question…

    Open the full PDF
    Your answer
  4. Q18(c)(i)

    June 2024 · Paper 1

    The whole paper ↗

    Loading the question…

    Open the full PDF
  5. Q18(c)(ii)

    June 2024 · Paper 1

    The whole paper ↗

    Loading the question…

    Open the full PDF
  6. Q6

    June 2024 · AS Paper 1

    The whole paper ↗

    Loading the question…

    Open the full PDF
    Your answer
  7. Q4(a)(i)

    June 2024 · AS Paper 2

    The whole paper ↗

    Loading the question…

    Open the full PDF
  8. Q4(a)(ii)

    June 2024 · AS Paper 2

    The whole paper ↗

    Loading the question…

    Open the full PDF
  9. Q4(a)(iii)

    June 2024 · AS Paper 2

    The whole paper ↗

    Loading the question…

    Open the full PDF
  10. Q4(b)(i)

    June 2024 · AS Paper 2

    The whole paper ↗

    Loading the question…

    Open the full PDF
  11. Q4(b)(ii)

    June 2024 · AS Paper 2

    The whole paper ↗

    Loading the question…

    Open the full PDF
  12. Q16(a)(iii)

    June 2023 · Paper 1

    The whole paper ↗
    The start of question 16

    Loading the start of the question…

    Loading the question…

    Open the full PDF
  13. Q2(d)(i)

    June 2022 · Paper 3

    The whole paper ↗

    Loading the question…

    Open the full PDF
  14. Q2(d)(ii)

    June 2022 · Paper 3

    The whole paper ↗

    Loading the question…

    Open the full PDF
  15. Q23(a)(i)

    June 2022 · AS Paper 1

    The whole paper ↗
    The start of question 23

    Loading the start of the question…

    Loading the question…

    Open the full PDF
  16. Q23(a)(ii)

    June 2022 · AS Paper 1

    The whole paper ↗
    The start of question 23

    Loading the start of the question…

    Loading the question…

    Open the full PDF
  17. Q23(a)(iii)

    June 2022 · AS Paper 1

    The whole paper ↗
    The start of question 23

    Loading the start of the question…

    Loading the question…

    Open the full PDF
  18. Q23(b)

    June 2022 · AS Paper 1

    The whole paper ↗
    The start of question 23

    Loading the start of the question…

    Loading the question…

    Open the full PDF
  19. Q21(a)(i)

    November 2021 · Paper 1

    The whole paper ↗
    The start of question 21

    Loading the start of the question…

    Loading the question…

    Open the full PDF
  20. Q21(a)(ii)

    November 2021 · Paper 1

    The whole paper ↗
    The start of question 21

    Loading the start of the question…

    Loading the question…

    Open the full PDF
All 34 questions on Blood vessels and tissue fluid, as a list
  1. June 2025, Paper 1, Q20(a) (3 marks): The table compares features of different types of blood vessel in mammals. Blood vessel type Feature E F G H Diameter of lumen largest large small smallest Thic
  2. June 2025, Paper 1, Q20(b) (1 mark): Unlike most other veins, pulmonary veins do not have valves. Suggest why valves are not needed in pulmonary veins. [1]
  3. June 2024, Paper 1, Q6 (1 mark): Lymph and tissue fluid are both formed from the blood. Which statement describes the composition of these fluids? A Lymph contains more protein than tissue flui
  4. June 2024, Paper 1, Q18(c)(i) (2 marks): The net pressure at the arteriole end is +1.3 kPa. Calculate the net pressure at the venule end. Net pressure at venule end = kPa [2]
  5. June 2024, Paper 1, Q18(c)(ii) (2 marks): Use the information in the table to explain the formation of tissue fluid and its return to the blood. [2]
  6. June 2024, AS Paper 1, Q6 (1 mark): Which option is a feature of tissue fluid? A Tissue fluid carries oxygen away from muscle cells B Tissue fluid does not contain erythrocytes C Tissue fluid form
  7. June 2024, AS Paper 2, Q4(a)(i) (1 mark): Scientists can measure the size of an aneurysm. An investigation measured the ratio of collagen to elastin in the blood vessel wall in five patients with an ane
  8. June 2024, AS Paper 2, Q4(a)(ii) (3 marks): Students looked at data on aneurysms in different groups of people of the same age. The table shows their findings. Observed frequency of Expected frequency of
  9. June 2024, AS Paper 2, Q4(a)(iii) (2 marks): The table shows part of a statistical table for the chi squared test. Probability (%) 10 5 1 0.5 df 1 2.706 3.841 6.635 7.879 2 4.605 5.991 9.210 10.60 3 6.251
  10. June 2024, AS Paper 2, Q4(b)(i) (2 marks): Explain the role of valves in veins. [2]
  11. June 2024, AS Paper 2, Q4(b)(ii) (3 marks): The smooth muscle content in some arteriole walls is more than double the smooth muscle content in the walls of some arteries. Explain how arterioles are better
  12. June 2023, Paper 1, Q16(a)(iii) (3 marks): Fig. 16.2 shows how blood pressure varies throughout pregnancy. Fig. 16.2 92 90 88 Mean arterial 86 pressure 84 (mmHg) 82 80 78 9–12 13–16 17–20 21–24 25–28 29–
  13. June 2022, Paper 3, Q2(d)(i) (2 marks): State whether L is an artery or a vein and give two pieces of evidence from Fig. 2.2 that allow you to reach your decision. L Evidence 1 Evidence 2 [2]
  14. June 2022, Paper 3, Q2(d)(ii) (1 mark): State the substance labelled N. [1]
  15. June 2022, AS Paper 1, Q23(a)(i) (1 mark): On the diagram, draw an arrow to show the direction of movement of blood through the [1] capillary network.
  16. June 2022, AS Paper 1, Q23(a)(ii) (2 marks): On the diagram, draw an arrow to show the direction in which oncotic pressure is acting and suggest a value for oncotic pressure. Write the value for oncotic pr
  17. June 2022, AS Paper 1, Q23(a)(iii) (1 mark): Name the structure labelled W. [1]
  18. June 2022, AS Paper 1, Q23(b) (3 marks): Describe how oncotic pressure is established. [3]
  19. November 2021, Paper 1, Q21(a)(i) (1 mark): State the effect on the water potential of the blood if the concentration of glucose increases. [1]
  20. November 2021, Paper 1, Q21(a)(ii) (2 marks): Explain why the oncotic pressure of the blood depends only on the concentration of large plasma proteins. [2]
  21. November 2021, Paper 1, Q21(b)(i) (2 marks): In one type of capillary the reflectance factor was found to be 0.75. Use this information and the data in the table to calculate a value for the net driving fo
  22. November 2021, Paper 1, Q21(b)(ii) (2 marks): Nephrotic syndrome is a kidney disease where protein is excreted in the urine. One group of patients with nephrotic syndrome had a plasma albumin concentration
  23. November 2021, Paper 1, Q21(b)(iii) (4 marks): A medical student concluded that a patient with kidney disease and a plasma albumin concentration of 0.015 g dm–3 would show signs of swelling, such as swollen
  24. November 2021, Paper 1, Q21(c) (2 marks): The table below contains statements about the composition of lymph and tissue fluid. Place ticks (✓) in the boxes in the table to indicate whether the statement
  25. November 2021, AS Paper 1, Q2 (1 mark): Which of the options, A to D, would result in the formation of tissue fluid? A hydrostatic pressure 1 oncotic pressure B hydrostatic pressure = oncotic pressure
  26. November 2021, AS Paper 2, Q2(c) (6 marks): (c)* Three types of blood vessels found in mammals are arteries, veins and capillaries. Fig. 2.3 shows data on these blood vessels. Elastic layer 330 μm Artery
  27. November 2020, AS Paper 1, Q7 (1 mark): The table below shows the different percentages of three different components of blood vessels. elastin (%) smooth muscle (%) collagen (%) A 8 33 58 B 17 39 43
  28. June 2019, Paper 1, Q19(a) (3 marks): Explain why the visible blood vessels are likely to be veins. [3]
  29. June 2018, Paper 3, Q6(a) (6 marks): The process of ultrafiltration in the kidney shares similarities with the formation of tissue fluid. (a)* Describe the similarities and differences between ultr
  30. June 2018, AS Paper 2, Q4(a)(ii) (2 marks): Dissolved ions diffuse between blood plasma and tissue fluid. Pressure differences at the arterial and venous ends of capillaries are responsible for the format
  31. June 2017, AS Paper 1, Q9 (1 mark): Which of the options, A to D, is a correct statement about tissue fluid? A Tissue fluid carries carbon dioxide to muscle cells. B Oncotic pressure in the capill
  32. June 2017, AS Paper 1, Q17 (1 mark): A student studied the structure of a blood vessel and found: • an outer layer of collagen fibres, • a thick middle layer of smooth muscle and elastic tissue, •
  33. June 2016, AS Paper 1, Q12 (1 mark): Pressure varies in different parts of the mammalian circulatory system. Blood in Blood in Tissue fluid Lymph aorta vena cava Pressure Which of the following opt
  34. June 2016, AS Paper 1, Q24(c)(ii) (2 marks): With reference to the structure of blood vessels, explain why oxygen is not released until the blood reaches the capillaries. [2]

Questions, mark schemes and examiner’s reports are © OCR, from their published past papers. Plumi isn’t affiliated with any exam board. Want whole papers? OCR A-Level Biology A past papers, or our free OCR-style practice pack.

The Plumi iPad app also offers exam-style questions with AI feedback on your handwritten working.