plumiChromatography: paper, TLC, HPLC and GC: Edexcel International A Level Chemistry questions
Edexcel International A Level Chemistry past-paper questions on 15.E.4 Chromatography: paper, TLC, HPLC and GC, 2019–2025, with mark schemes and examiner’s reports where available.
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All 22 questions on Chromatography: paper, TLC, HPLC and GC, as a list
- June 2025, Unit 4, Q8 (1 mark): A thin layer chromatogram of a substance is shown. solvent front position of sample starting point What is the Rf value of the sample? A 0.27 B 0.69 C 0.73 D 1.
- June 2025, Unit 5, Q17(c)(i) (2 marks): Briefly describe how trimethylamine will be separated from other chemicals present in the sample of air. (2)
- June 2025, Unit 5, Q17(c)(ii) (1 mark): High-performance liquid chromatography (HPLC) is used to measure levels of trimethylamine and trimethylamine N-oxide in blood and urine. Label the x-axis on the
- June 2025, Unit 5, Q17(c)(iii) (1 mark): Name the analytical technique that can be used with either GC or HPLC to identify the compound responsible for each peak. (1)
- January 2025, Unit 4, Q20(e)(i) (1 mark): High-performance liquid chromatography, HPLC, is used for analysis in the extraction process. The HPLC equipment is connected to a detector which records peaks
- October 2024, Unit 4, Q3(c) (1 mark): A sample containing 2 × 10–9 g cm–3 of nandrolone was analysed using gas chromatography. The chromatogram produced is shown. Absorption 0 1 2 3 4 5 6 7 8 9 Rete
- October 2023, Unit 4, Q13(a) (1 mark): What is the Rf value for compound X? (1) A 0.33 B 0.38 C 0.60 D 0.62
- October 2023, Unit 4, Q13(b) (1 mark): Y travelled further than X. How do the attractions between Y and X to the stationary and mobile phases compare? (1) Attraction between Y and the Attraction betw
- June 2023, Unit 4, Q4(a) (1 mark): Which is correct for the labels on the axes? (1) x-axis y-axis A absorption time B Rf absorption C time Rf D time absorption
- June 2023, Unit 4, Q4(b) (1 mark): Which is correct for the components E, F and G ? (1) Most attracted to Most abundant stationary phase A E E B G E C E F D G F
- January 2023, Unit 4, Q16 (1 mark): The chromatogram of a substance X is shown. solvent front substance X baseline What is the Rf value for substance X? A 0.28 B 0.62 C 0.70 D 0.86
- January 2023, Unit 5, Q13 (1 mark): A student hydrolysed a section of a protein and then used thin-layer chromatography to analyse the amino acids produced. The chromatogram is shown. solvent fron
- October 2022, Unit 4, Q14 (1 mark): Which change decreases the retention time in gas chromatography? A decreasing the column temperature B increasing the carrier gas flow rate C decreasing the amo
- June 2022, Unit 4, Q3 (1 mark): A high performance liquid chromatography (HPLC) system used a column with a non‑polar stationary phase and a solvent of methanol and water. A mixture of octane,
- June 2022, Unit 4, Q4 (1 mark): A diagram of a thin layer chromatogram of substance Y is shown. solvent front position of substance Y baseline What is the Rf value of substance Y? A 0.25 B 0.6
- January 2022, Unit 4, Q16 (1 mark): In gas chromatography, a gas containing a mixture is passed over a liquid stationary phase. The main reason a mixture is separated into its components is becaus
- January 2022, Unit 4, Q17 (1 mark): In HPLC, the mobile and stationary phases are Mobile phase Stationary phase A gas liquid B gas solid C liquid gas D liquid solid
- June 2021, Unit 4, Q11(a) (1 mark): A spot caused by an amino acid has moved 42 mm from the baseline of a paper chromatogram. The Rf value for the amino acid under these conditions is 0.62. What i
- June 2021, Unit 4, Q11(b) (1 mark): In gas chromatography, GC, which of these would be the most suitable carrier gas? (1) A argon B hydrogen C methane D oxygen Use this space for any rough working
- January 2021, Unit 4, Q16 (1 mark): A mixture of organic compounds was analysed using thin-layer chromatography. The Rf value was 0.92 for one of the components in the mixture. What can be deduced
- January 2020, Unit 4, Q16(b)(i) (3 marks): Complete the diagram below, showing a chromatogram for ethyl 3-oxobutanoate, including appropriate labels. (3)
- January 2020, Unit 4, Q16(b)(ii) (2 marks): Suggest why the Rf value for ethyl 3-oxobutanoate is significantly lower than 0.45 when just hexane is used as the solvent. (2)
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