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Pathogen entry and barriers to infection: Edexcel International A Level Biology questions

Edexcel International A Level Biology past-paper questions on 6.3.1 Pathogen entry and barriers to infection, 2019–2025, with mark schemes and examiner’s reports where available.

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3,127 questions

  1. Q2(a)

    June 2025 · Unit 4

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  2. Q8(a)

    January 2025 · Unit 4

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  3. Q1(a)

    January 2024 · Unit 4

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  4. Q1(b)(i)

    January 2024 · Unit 4

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  5. Q1(b)(ii)

    January 2024 · Unit 4

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  6. Q4(b)(i)

    October 2023 · Unit 4

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  7. Q4(b)(ii)

    October 2023 · Unit 4

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  8. Q6(a)

    June 2023 · Unit 4

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  9. Q7(b)

    October 2022 · Unit 4

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  10. Q3(a)(i)

    June 2022 · Unit 4

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  11. Q3(a)(ii)

    June 2022 · Unit 4

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  12. Q3(b)(i)

    June 2022 · Unit 4

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  13. The start of question 8

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  14. Q2(c)(i)

    January 2021 · Unit 4

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  15. Q8(b)(i)

    October 2020 · Unit 4

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  16. Q8(b)(ii)

    October 2020 · Unit 4

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All 16 questions on Pathogen entry and barriers to infection, as a list
  1. June 2025, Unit 4, Q2(a) (1 mark): Gut flora are important as they help protect the body from pathogens. State the meaning of the term pathogen. (1)
  2. January 2025, Unit 4, Q8(a) (2 marks): The diagram shows the distribution of cholera cases by age group and sex at birth in Malawi, in the first nine months of 2022. Key: females males 91 to 100 81 t
  3. January 2024, Unit 4, Q1(a) (1 mark): Which of the following also act as barriers, protecting the body from infection by bacteria? (1) A antigens and stomach acid B antigens and interferon C interfe
  4. January 2024, Unit 4, Q1(b)(i) (2 marks): Describe two conclusions that can be made about the different methods of washing hands. (2)
  5. January 2024, Unit 4, Q1(b)(ii) (2 marks): Explain the differences in the effects that these methods of washing hands have on the skin flora. (2)
  6. October 2023, Unit 4, Q4(b)(i) (2 marks): The effect on the types of bacteria in the guts of babies fed on breast milk or another source of milk was investigated. The graph shows the proportion of five
  7. October 2023, Unit 4, Q4(b)(ii) (2 marks): Explain the importance of healthy gut flora in preventing infection in a developing baby. (2)
  8. June 2023, Unit 4, Q6(a) (1 mark): State the meaning of the term infection. (1)
  9. October 2022, Unit 4, Q7(b) (2 marks): Explain why it is important that Castaneroxy A does not affect skin flora. (2)
  10. June 2022, Unit 4, Q3(a)(i) (2 marks): Describe how skin flora protect the body from infection. (2)
  11. June 2022, Unit 4, Q3(a)(ii) (1 mark): Give one other way in which the skin protects the body from infection. (1)
  12. June 2022, Unit 4, Q3(b)(i) (3 marks): Describe three conclusions that could be made from this graph. (3)
  13. October 2021, Unit 5, Q8(d) (4 marks): Explain how the bacterium Porphyromonas gingivalis that causes gum disease may invade the brain and cause inflammation in brain regions affected by Alzheimer’s
  14. January 2021, Unit 4, Q2(c)(i) (2 marks): Explain the role of gut flora in protecting the body from infection. (2)
  15. October 2020, Unit 4, Q8(b)(i) (2 marks): Explain why bacteria living in our intestines are important. (2)
  16. October 2020, Unit 4, Q8(b)(ii) (2 marks): Both the molecules on the membranes of the cells lining our intestines and the antigens on red blood cells have sugars attached to protein molecules. Bacteria l

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