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Microarrays and bioinformatics: Edexcel International A Level Biology questions

Edexcel International A Level Biology past-paper questions on 8.6.3 Microarrays and bioinformatics, 2019–2025, with mark schemes and examiner’s reports where available.

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  1. Q8(f)

    October 2024 · Unit 5

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  2. Q8(a)

    June 2024 · Unit 5

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  3. Q5(a)

    January 2024 · Unit 5

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  4. Q8(g)

    June 2023 · Unit 5

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  5. Q8(b)

    October 2022 · Unit 5

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  6. Q8(f)

    October 2022 · Unit 5

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  7. Q8(b)

    January 2022 · Unit 5

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  8. Q8(c)

    January 2022 · Unit 5

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  9. Q8(f)

    October 2021 · Unit 5

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  10. Q5(c)

    January 2021 · Unit 5

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  11. Q7(c)

    October 2020 · Unit 5

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All 11 questions on Microarrays and bioinformatics, as a list
  1. October 2024, Unit 5, Q8(f) (3 marks): Some genes may be linked to an increase in the risk of dementia. Describe how scientists could identify the link between these genes and the risk of dementia (P
  2. June 2024, Unit 5, Q8(a) (3 marks): Explain how Ted Turlings and colleagues could have identified that the BtPMaT1 gene found in the whitefly was originally a plant gene (paragraph 2). (3)
  3. January 2024, Unit 5, Q5(a) (2 marks): Describe how active genes could be identified. (2)
  4. June 2023, Unit 5, Q8(g) (3 marks): Gut microorganisms produce LPS (paragraphs 15 and 17). White blood cells have receptors for LPS on their cell surface. Describe the techniques that could be use
  5. October 2022, Unit 5, Q8(b) (3 marks): Suggest how the genes expressed in a sensory neurone could be identified (paragraph 4). (3)
  6. October 2022, Unit 5, Q8(f) (2 marks): Explain what is meant by the phrase ‘Based on its similarity to Piezo 1, a second ion channel was found (Piezo 2)’ (paragraph 7 and Figure 3). (2)
  7. January 2022, Unit 5, Q8(b) (2 marks): Suggest how the genes affected by toxicants can be identified (paragraph 4). (2)
  8. January 2022, Unit 5, Q8(c) (3 marks): Explain how scientists could determine the high degree of homology of genes between humans and zebrafish (paragraph 5). (3)
  9. October 2021, Unit 5, Q8(f) (3 marks): The team found genetic material from P. gingivalis in the cerebral cortex (paragraph 13). Describe how the team could show that this genetic material is active.
  10. January 2021, Unit 5, Q5(c) (3 marks): Mutations in other genes can result in blindness. Describe how these genes could be identified. (3)
  11. October 2020, Unit 5, Q7(c) (4 marks): Describe how microarrays and bioinformatics could be used to investigate the genetic basis of Parkinson’s disease. (4)

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