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Drugs from genetically modified organisms: Edexcel International A Level Biology questions

Edexcel International A Level Biology past-paper questions on 8.6.1 Drugs from genetically modified organisms, 2019–2025, with mark schemes and examiner’s reports where available.

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  1. Q7(d)(ii)

    June 2025 · Unit 5

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  2. Q5(c)(ii)

    January 2025 · Unit 5

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  3. Q7(b)(i)

    October 2024 · Unit 5

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  4. Q5(c)

    October 2023 · Unit 5

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  5. Q7(a)(ii)

    October 2022 · Unit 5

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  6. Q4(b)(i)

    June 2022 · Unit 5

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  8. The start of question 8

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  9. Q8(e)(ii)

    January 2021 · Unit 5

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All 9 questions on Drugs from genetically modified organisms, as a list
  1. June 2025, Unit 5, Q7(d)(ii) (2 marks): Suggest one advantage and one disadvantage of using genetically modified mouse cells rather than E. coli bacteria to produce human GH. (2)
  2. January 2025, Unit 5, Q5(c)(ii) (2 marks): Suggest two advantages of producing human insulin using genetically modified bacteria compared with insulin produced from animals. (2)
  3. October 2024, Unit 5, Q7(b)(i) (3 marks): Describe three conclusions that can be made from these results. (3) .
  4. October 2023, Unit 5, Q5(c) (4 marks): The genetically engineered E. coli was grown in a liquid culture. The concentrations of tryptophan and serotonin in the culture were measured. The graph shows t
  5. October 2022, Unit 5, Q7(a)(ii) (1 mark): In a clinical study, 4382 patients were treated with rHE. They showed a mean increase in blood haemoglobin from 80 g dm–3 to 142 g dm–3. Calculate the percentag
  6. June 2022, Unit 5, Q4(b)(i) (4 marks): Explain the effects of these three genes in this investigation. (4)
  7. October 2021, Unit 5, Q2(a) (4 marks): Describe how genetic engineering could be used to produce rice that contains β‑carotene. (4)
  8. January 2021, Unit 5, Q8(e)(i) (4 marks): Describe how insect cells could be genetically modified to produce the antigens for an Ebola vaccine. (4)
  9. January 2021, Unit 5, Q8(e)(ii) (3 marks): Suggest three benefits of using an insect cell to produce the Ebola virus antigen. (3)

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