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Analysing health risk data and studies: Edexcel International A Level Biology questions

Edexcel International A Level Biology past-paper questions on 1.4.1 Analysing health risk data and studies, 2019–2025, with mark schemes and examiner’s reports where available.

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  1. Q8(a)

    June 2025 · AS Unit 1

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  2. Q8(c)(i)

    June 2025 · AS Unit 1

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  3. Q8(c)(ii)

    June 2025 · AS Unit 1

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  4. Q8(c)(v)

    June 2025 · AS Unit 1

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  5. The start of question 8

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  6. Q2(b)(i)

    January 2025 · AS Unit 1

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  7. Q2(b)(ii)

    January 2025 · AS Unit 1

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  8. Q2(b)(iii)

    January 2025 · AS Unit 1

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  9. Q2(b)(iv)

    January 2025 · AS Unit 1

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  11. The start of question 6

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  12. Q8(b)(i)

    October 2024 · AS Unit 1

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  13. Q8(b)(ii)

    October 2024 · AS Unit 1

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  14. Q8(b)(iii)

    October 2024 · AS Unit 1

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  15. Q7(c)(ii)

    June 2024 · AS Unit 1

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  16. Q7(c)(iii)

    June 2024 · AS Unit 1

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  17. Q5(d)(i)

    January 2024 · AS Unit 1

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  18. The start of question 7

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  19. Q8(a)(i)

    October 2023 · AS Unit 1

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  20. Q8(a)(ii)

    October 2023 · AS Unit 1

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All 58 questions on Analysing health risk data and studies, as a list
  1. June 2025, AS Unit 1, Q8(a) (2 marks): Towards the end of 2023, the world’s population was 8 078 799 080. Approximately 70% of this population were adults. Estimate the number of adults in the world.
  2. June 2025, AS Unit 1, Q8(c)(i) (1 mark): Give the meaning of the term correlation. (1)
  3. June 2025, AS Unit 1, Q8(c)(ii) (3 marks): It was important that all the people in the study had similar blood pressure that was within a healthy range. Explain why this was important. (3)
  4. June 2025, AS Unit 1, Q8(c)(v) (4 marks): The graphs show some of the results from this study. 20 Key: 16 males females 12 Proportion of healthy endothelial cells / a.u. 8 4 0 0 2 4 6 8 Number of neutro
  5. June 2025, Unit 5, Q8(d) (3 marks): Describe how the cardiovascular health of participants in the UK Biobank study could be assessed (paragraph 6). (3)
  6. January 2025, AS Unit 1, Q2(b)(i) (3 marks): Compare and contrast the number of deaths caused by these cancers in ethnic groups 1 and 2. (3)
  7. January 2025, AS Unit 1, Q2(b)(ii) (1 mark): Which is the percentage difference between the number of deaths caused by lung and bronchus cancer in ethnic group 1 and ethnic group 3? Use the formula: differ
  8. January 2025, AS Unit 1, Q2(b)(iii) (1 mark): Calculate how many more males died of prostate cancer in ethnic group 2 than in ethnic group 1. (1) Answer
  9. January 2025, AS Unit 1, Q2(b)(iv) (2 marks): Comment on how useful it is to determine the number of deaths from these causes of cancer in the ‘all ethnic groups’ part of this graph. (2)
  10. January 2025, AS Unit 1, Q4(c)(iii) (3 marks): The graphs show the BMI and WHR of the men and women who died due to either CVD or CHD. Key: men women 15 10 Percentage of people who died due to 5 cardiovascul
  11. January 2025, AS Unit 1, Q6(a) (2 marks): The graph shows the relationship between blood cholesterol levels and the coronary heart disease death rate in men in four parts of the world. Key: Northern Eur
  12. October 2024, AS Unit 1, Q8(b)(i) (1 mark): There were 41 701 men and 68 786 women in the group. Which is the ratio of men to women? (1) A 0.6 : 1 B 1 : 0.6 C 1 : 2 D 2 : 1
  13. October 2024, AS Unit 1, Q8(b)(ii) (6 marks): Describe the questions that need to be in the questionnaire so that appropriate information can be gathered for this investigation. Give reasons for choosing th
  14. October 2024, AS Unit 1, Q8(b)(iii) (4 marks): Comment on the validity of the methods used in this investigation. (4)
  15. June 2024, AS Unit 1, Q7(c)(ii) (4 marks): Describe how an investigation could be designed to identify any side effects of treatment with monacolin K. (4)
  16. June 2024, AS Unit 1, Q7(c)(iii) (2 marks): Suggest two problems when assessing possible side effects resulting from treatment with monacolin K in an investigation. (2) 1 2
  17. January 2024, AS Unit 1, Q5(d)(i) (2 marks): Explain why this finding can be described as a positive correlation. (2)
  18. October 2023, AS Unit 1, Q7(a) (2 marks): In one investigation, scientists measured the blood cholesterol level in a group of people and monitored the development of heart disease in the following 10 ye
  19. October 2023, AS Unit 1, Q8(a)(i) (2 marks): Calculate how many global deaths there are in one year. Express your answer in standard form. (2) Answer
  20. October 2023, AS Unit 1, Q8(a)(ii) (2 marks): It is predicted that by 2030 more than 22.2 million people will die each year from CVDs. Suggest how this prediction was made. (2)
  21. October 2023, AS Unit 1, Q8(b)(ii) (1 mark): There is very little data available to show that these rhizomes reduce the risk of CVD. Suggest why these rhizomes can be eaten to prevent CVD even though their
  22. October 2023, AS Unit 1, Q8(b)(iii) (6 marks): Explain how a study should be designed to collect valid and repeatable data to show the effectiveness of using ginger in preventing CVD. (6)
  23. June 2023, AS Unit 1, Q8(b) (6 marks): Explain the effectiveness of these two calculators in the assessment of risk and whether other factors should be considered. (6)
  24. June 2023, AS Unit 1, Q8(c)(ii) (2 marks): Suggest why these two risk calculators may not be suitable for everybody to use. (2)
  25. January 2023, AS Unit 1, Q5(b)(i) (1 mark): Some of the women were removed from the initial group because there was information missing about their lifestyles. Suggest why women with missing lifestyle inf
  26. January 2023, AS Unit 1, Q5(b)(ii) (2 marks): Some of the women were removed from the initial group because they gave unrealistic estimates of their daily energy intake. Give two reasons why some women may
  27. January 2023, AS Unit 1, Q5(b)(iii) (2 marks): The women removed from the intermediary group had signs of CVD. Explain why these women were removed from this investigation. (2)
  28. January 2023, AS Unit 1, Q5(b)(iv) (1 mark): Calculate the percentage of all the women removed from this investigation. (1) Answer %
  29. January 2023, Unit 5, Q5(c)(i) (2 marks): Calculate the total number of people in this age group that will have lung cancer who are non-smokers with COPD. Give your answer in standard form. (2) Answer
  30. October 2022, AS Unit 1, Q6(d)(ii) (4 marks): A second study compared this result with people given a combination of warfarin and aspirin. Describe how this study should be carried out to produce a valid co
  31. October 2022, AS Unit 1, Q7(e) (6 marks): Type 2 diabetes is a disorder that can result from ineffective or insufficient insulin. It is a risk factor for cardiovascular disease (CVD). Cinnamon is a spic
  32. June 2022, AS Unit 1, Q6(a)(ii) (3 marks): Explain how this study should have been designed to allow valid conclusions to be made. (3)
  33. June 2022, AS Unit 1, Q6(b)(i) (2 marks): Calculate the 10-year risk of CVD for a 35-year-old woman who: • has a total cholesterol level of 242 mg dm−3 • is a smoker • has a systolic blood pressure of 1
  34. June 2022, AS Unit 1, Q6(b)(iv) (2 marks): Suggest why this method of determining the 10-year risk of CVD may not be accurate. (2)
  35. January 2022, AS Unit 1, Q7(b)(ii) (3 marks): Some studies do not assess the nutritional quality of the diet of the participants. Explain why the results of these studies have to be treated with caution. (3
  36. October 2021, AS Unit 1, Q1(c) (3 marks): The graph shows the number of cases of one type of cancer in a human population. 4000 3000 Number of cases of cancer per 100 000 Key population Male 2000 Female
  37. October 2021, AS Unit 1, Q5(a) (2 marks): Explain how this data shows that there is a correlation between the age of the women and the miscarriage rate. (2)
  38. October 2021, AS Unit 1, Q5(b)(ii) (3 marks): Explain why conclusions made using these data may not be valid. (3)
  39. October 2021, Unit 5, Q4(d)(i) (3 marks): Comment on the results of this trial. (3)
  40. June 2021, AS Unit 1, Q2(c)(i) (1 mark): One estimate is that there are 415 million people with diabetes in the world and that 46% of these people are undiagnosed. Calculate the number of people who ha
  41. June 2021, AS Unit 1, Q7(b)(i) (1 mark): The graphs show some correlations. State the meaning of the term correlation. (1)
  42. June 2021, AS Unit 1, Q7(b)(ii) (3 marks): Describe the correlations shown by these graphs. (3)
  43. June 2021, AS Unit 1, Q7(b)(iii) (3 marks): Suggest a reason for each of the correlations shown by these graphs. (3)
  44. June 2021, AS Unit 1, Q7(c) (6 marks): The table shows some information from a study of the incidence of emphysema in smokers and non‑smokers. Information Males Females Number of individuals in the s
  45. January 2021, AS Unit 1, Q6(a)(i) (2 marks): The graph shows that there is a correlation between smoking and death rate from lung cancer in men. Death rate Cigarettes smoked Number of cigarettes Death rate
  46. January 2021, AS Unit 1, Q7(c)(ii) (3 marks): Devise a study to confirm that antioxidants reduce the risk of CVD. (3)
  47. January 2021, AS Unit 2, Q7(b) (1 mark): In 2017, an estimated 219 million people in 87 countries had malaria, and 435 000 of these people died. Which of the following shows the percentage of infected
  48. October 2020, AS Unit 1, Q5(c)(i) (3 marks): The table shows the results of this study. Mean body mass of the group of women / kg Number of weeks on the diet Group on the Group on the very low‑fat diet low
  49. October 2020, AS Unit 1, Q7(d) (4 marks): Other drugs are available that work in a similar way to warfarin. The diagram shows one study to compare the effect of warfarin with drug X. Two groups of peopl
  50. October 2020, AS Unit 2, Q5(b) (3 marks): The graph shows the probability of survival for different stages of a cancer, after diagnosis. 100 Stage I 75 Probability of survival (%) Stage II 50 25 Stage I
  51. January 2020, AS Unit 1, Q6(a) (2 marks): State two conclusions that can be drawn from these results. (2) 1 2
  52. January 2020, AS Unit 1, Q6(b)(i) (3 marks): Explain why age and smoking were taken into account when determining the hazard ratio. (3)
  53. January 2020, AS Unit 1, Q6(b)(ii) (2 marks): State two factors, other than age and smoking, that may have been considered when adjusting the values for the hazard ratio. (2) 1 2
  54. January 2020, AS Unit 1, Q6(c) (2 marks): Suggest why the hazard ratio for low salt intake was 1.00 for each cause of death. (2)
  55. January 2020, AS Unit 1, Q6(d)(i) (1 mark): The results of this study suggest that there is a correlation between salt intake and cause of death. State the meaning of the term correlation. (1)
  56. January 2020, AS Unit 1, Q6(d)(ii) (2 marks): Suggest why studies of this type are unreliable. (2)
  57. June 2019, AS Unit 1, Q6(b)(iii) (3 marks): Describe how a study could be designed to collect valid and reliable data on the effects of eating chocolate on the risk of CVD. (3)
  58. January 2019, AS Unit 1, Q2(d)(iii) (2 marks): A person used this risk calculator. Explain why the value obtained for the 10 Year CHD Risk may be an underestimate. (2)

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