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Alteration of the sequence of bases in DNA can alter the structure of proteins: AQA A‑Level Biology questions

Every AQA A-Level Biology exam question on 3.8.1 Alteration of the sequence of bases in DNA can alter the structure of proteins, 2016–2025, with its mark scheme and examiner’s report.

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1,383 questions

  1. Q04.1

    June 2025 · Paper 2

    4 marks3.8.1 Alteration of the sequence of bases in DNA can alter the structure of proteins
    The whole paper ↗
    June 2025 Paper 2, question 04.1: People with the inherited blood disorder haemophilia A (HA) have a reduced ability to clot blood. One variant of HA is due to an inversion mutation in the F8 ge

  2. Q05.1

    June 2024 · Paper 3

    2 marks3.8.1 Alteration of the sequence of bases in DNA can alter the structure of proteins
    The whole paper ↗
    June 2024 Paper 3, question 05.1: Name one type of SURF1 gene mutation and explain how this mutation could lead to production of a shorter polypeptide. [2 marks] Type of mutation Explanation Glo

  3. Q01.5

    November 2021 · Paper 3

    3 marks3.8.1 Alteration of the sequence of bases in DNA can alter the structure of proteins
    The whole paper ↗
    November 2021 Paper 3, question 01.5: Use Figure 1 and this information to suggest why S. carolinensis with the genotype C BC B have black fur rather than grey fur. [3 marks]

  4. Q02.1

    June 2019 · Paper 2

    3 marks3.8.1 Alteration of the sequence of bases in DNA can alter the structure of proteins
    The whole paper ↗
    June 2019 Paper 2, question 02.1: Explain how a single base substitution causes a change in the structure of this polypeptide. Do not include details of transcription and translation in your ans

  5. Q02.1

    June 2018 · Paper 2

    1 mark3.8.1 Alteration of the sequence of bases in DNA can alter the structure of proteins
    The whole paper ↗
    June 2018 Paper 2, question 02.1: There are different types of gene mutation. Put a tick () in the box next to the statement which describes incorrectly the effect of the mutation in an exon of

  6. Q06.4

    Specimen · Paper 2

    2 marks3.8.1 Alteration of the sequence of bases in DNA can alter the structure of proteins
    The whole paper ↗
    Specimen Paper 2, question 06.4: 6
All 6 questions on Alteration of the sequence of bases in DNA can alter the structure of proteins, as a list
  1. June 2025, Paper 2, Q04.1 (4 marks): People with the inherited blood disorder haemophilia A (HA) have a reduced ability to clot blood. One variant of HA is due to an inversion mutation in the F8 ge
  2. June 2024, Paper 3, Q05.1 (2 marks): Name one type of SURF1 gene mutation and explain how this mutation could lead to production of a shorter polypeptide. [2 marks] Type of mutation Explanation Glo
  3. November 2021, Paper 3, Q01.5 (3 marks): Use Figure 1 and this information to suggest why S. carolinensis with the genotype C BC B have black fur rather than grey fur. [3 marks]
  4. June 2019, Paper 2, Q02.1 (3 marks): Explain how a single base substitution causes a change in the structure of this polypeptide. Do not include details of transcription and translation in your ans
  5. June 2018, Paper 2, Q02.1 (1 mark): There are different types of gene mutation. Put a tick () in the box next to the statement which describes incorrectly the effect of the mutation in an exon of
  6. Specimen, Paper 2, Q06.4 (2 marks): 6

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