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How is genetic information inherited?: OCR GCSE Biology B questions

Every OCR GCSE Biology B exam question on B1.2 How is genetic information inherited?, 2018–2025, with its mark scheme and examiner’s report.

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1,448 questions

  1. Q8(a)

    June 2025 · Paper 1 Foundation

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    The start of question 8
  2. Q8(b)(i)

    June 2025 · Paper 1 Foundation

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  3. Q8(b)(ii)

    June 2025 · Paper 1 Foundation

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  4. Q9(a)(i)

    June 2025 · Paper 3 Higher

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    The start of question 9
  5. Q9(a)(ii)

    June 2025 · Paper 3 Higher

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  6. Q8(a)

    June 2025 · Paper 4 Higher

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  7. Q8(b)

    June 2025 · Paper 4 Higher

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  8. Q5(a)

    June 2024 · Paper 1 Foundation

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    The start of question 5
  9. Q5(b)

    June 2024 · Paper 1 Foundation

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  10. Q5(c)

    June 2024 · Paper 1 Foundation

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  11. Q11(a)

    June 2024 · Paper 3 Higher

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  12. Q11(b)(i)

    June 2024 · Paper 3 Higher

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  13. Q11(b)(ii)

    June 2024 · Paper 3 Higher

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  14. Q2(a)

    June 2023 · Paper 1 Foundation

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  15. Q2(b)

    June 2023 · Paper 1 Foundation

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  16. Q10(a)

    June 2023 · Paper 3 Higher

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    The start of question 10
  17. Q10(c)

    June 2023 · Paper 3 Higher

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  18. Q7(d)(i)

    June 2023 · Paper 4 Higher

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  19. Q7(d)(ii)

    June 2023 · Paper 4 Higher

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  20. Q7(d)(iii)

    June 2023 · Paper 4 Higher

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    The start of question 7
All 67 questions on How is genetic information inherited?, as a list
  1. June 2025, Paper 1 Foundation, Q8(a) (1 mark): How many of the three children have thalassaemia? Number of children with thalassaemia = [1]
  2. June 2025, Paper 1 Foundation, Q8(b)(i) (1 mark): Which of the following describes the parents’ genotype? Tick (✓) one box. Heterozygous Homozygous dominant Homozygous recessive [1]
  3. June 2025, Paper 1 Foundation, Q8(b)(ii) (3 marks): The parents decide to have another child. Complete the Punnett square to find the probability that the child will have thalassaemia. Use T to represent the domi
  4. June 2025, Paper 3 Higher, Q9(a)(i) (3 marks): Describe the evidence from the family tree that supports this statement: ‘Thalassaemia is caused by a recessive allele.’ [3]
  5. June 2025, Paper 3 Higher, Q9(a)(ii) (3 marks): Individual W has a child with a female who is homozygous dominant for this genetic disorder. Calculate the probability that this child has thalassaemia. Probabi
  6. June 2025, Paper 4 Higher, Q8(a) (4 marks): Draw lines to connect each example to its correct description. Example Description Dominant allele Dominant phenotype R Heterozygous genotype Rr Homozygous domi
  7. June 2025, Paper 4 Higher, Q8(b) (4 marks): Gregor Mendel investigated the inheritance of round and wrinkled peas in the 1860s. Here are the steps Mendel took in one experiment: Step 1: Mendel bred one RR
  8. June 2024, Paper 1 Foundation, Q5(a) (3 marks): Complete the Punnett square to show that a bird breeder has a 0.5 probability of each offspring being male or female. Sperm cells Egg cells [3]
  9. June 2024, Paper 1 Foundation, Q5(b) (2 marks): Complete the table to compare sex determination in birds and humans. Tick (✓) one box in each row. Both birds Only birds Only humans and humans Sex is determine
  10. June 2024, Paper 1 Foundation, Q5(c) (3 marks): Describe how a human male baby develops male characteristics. [3]
  11. June 2024, Paper 3 Higher, Q11(a) (2 marks): Explain why cat breeders will be more concerned about a genetic condition that is caused by a dominant allele than a recessive allele. [2]
  12. June 2024, Paper 3 Higher, Q11(b)(i) (4 marks): Show how these cats could produce kittens that have PKD. Use a Punnett square. Use D to represent the dominant allele and d to represent the recessive allele. [
  13. June 2024, Paper 3 Higher, Q11(b)(ii) (2 marks): When the male homozygous recessive cat mates with the female heterozygous cat, they have 2 kittens. Calculate the probability that both kittens have PKD. Probab
  14. June 2023, Paper 1 Foundation, Q2(a) (4 marks): Two cocker spaniels have a puppy. • One of the parents has black fur and the alleles Bb. • The other parent has brown fur and the alleles bb. Calculate the prob
  15. June 2023, Paper 1 Foundation, Q2(b) (1 mark): is recessive. (b) Complete the sentence to explain why many other fur colours and patterns are seen in cocker spaniels. Put a ring around the correct option. Ma
  16. June 2023, Paper 3 Higher, Q10(a) (3 marks): Jane is 31, and she has started to develop symptoms of the condition. Neither of her parents has the disease. Calculate the probability that Jane has haemochrom
  17. June 2023, Paper 3 Higher, Q10(c) (4 marks): There are three common variations that cause this condition. The table shows the number of people with each of the three common variations. Variation Number of
  18. June 2023, Paper 4 Higher, Q7(d)(i) (1 mark): What is the phenotype of an elephant that has the genotype XT Xt? [1]
  19. June 2023, Paper 4 Higher, Q7(d)(ii) (2 marks): Explain why no female elephants are born homozygous for the no-tusks allele. [2]
  20. June 2023, Paper 4 Higher, Q7(d)(iii) (2 marks): A female elephant that is heterozygous for the no-tusks allele has a baby. Complete the Punnett square to show the possible genotypes of the baby. Father’s game
  21. June 2023, Paper 4 Higher, Q7(d)(iv) (2 marks): A scientist concludes that this female elephant is likely to have twice as many female offspring as male offspring. Explain why the scientist is correct. [2]
  22. June 2022, Paper 1 Foundation, Q9(b) (3 marks): Sickle cell anaemia is an inherited disease. The disease is caused by a recessive allele. The recessive allele is represented with an a, and the dominant allele
  23. June 2022, Paper 1 Foundation, Q14(a) (2 marks): Explain how sex determination in humans is different to sex determination in turtles. [2]
  24. June 2022, Paper 1 Foundation, Q14(b)(i) (3 marks): In some locations in 2020 the female turtles outnumbered male turtles in a ratio of 116 : 1. Calculate the number of female turtles in a sample of 18 000 turtle
  25. June 2022, Paper 1 Foundation, Q14(b)(iii) (1 mark): Suggest how scientists could help return the sex ratio in the next generation of turtles to that seen in the 1970s. [1]
  26. June 2022, Paper 2 Foundation, Q6(a)(i) (1 mark): State the genotype of ‘parent’ plant 1. [1]
  27. June 2022, Paper 2 Foundation, Q6(a)(ii) (1 mark): Describe the phenotype of ‘parent’ plant 2. [1]
  28. June 2022, Paper 2 Foundation, Q6(a)(iii) (1 mark): What is the probability that a plant in the ‘first generation’ will have red flowers? Put a ring around the correct answer. 0.25 0.5 1 4 [1]
  29. June 2022, Paper 2 Foundation, Q6(a)(iv) (2 marks): What can you conclude about the R and r alleles? Use the information in Table 6.1 and Fig. 6.1 to help you. R allele
  30. June 2022, Paper 2 Foundation, Q6(b)(i) (1 mark): Describe the flower colours Mendel would have observed in the ‘second generation’ of offspring. Flower colour of plants with alleles RR Flower colour of plants
  31. June 2022, Paper 2 Foundation, Q6(b)(ii) (2 marks): Calculate the percentage of plants in the ‘second generation’ that have the alleles Rr. Percentage = % [2]
  32. June 2022, Paper 2 Foundation, Q6(b)(iii) (1 mark): What can you conclude about the ratio of red flowered plants to white flowered plants in the ‘second generation’? Ratio of red flowered plants to white flowered
  33. June 2022, Paper 3 Higher, Q3(a) (2 marks): Explain how sex determination in humans is different to sex determination in turtles. [2]
  34. June 2022, Paper 3 Higher, Q3(b) (6 marks): The effect of temperature on the sex of the offspring is shown in the table. Egg incubation temperature (°C) Sex of offspring Below 27.7 male mix of male and fe
  35. November 2021, Paper 1 Foundation, Q11(b) (1 mark): Charlie and Eve find out they both have the genotype Tt. What word is used to describe this genotype? [1]
  36. November 2021, Paper 1 Foundation, Q11(c) (3 marks): Charlie and Eve still want to have a child. Complete the Punnett square to find out the probability of their child having Tay-Sachs disease. Probability of chil
  37. November 2021, Paper 2 Foundation, Q7(c)(i) (2 marks): Describe what evidence her genome would have contained to show that she was female. [2]
  38. November 2021, Paper 3 Higher, Q2(b) (1 mark): Charlie and Eve find out they both have the genotype Tt. What word is used to describe this genotype? [1]
  39. November 2021, Paper 3 Higher, Q2(c) (3 marks): Charlie and Eve still want to have a child. Complete the Punnett square to find out the probability of their child having Tay-Sachs disease. Probability of chil
  40. November 2021, Paper 3 Higher, Q5(b)(ii) (1 mark): A student talks about DNA with their friend. The student tells their friend that all features in a person’s phenotype are controlled by single genes in their DN
  41. November 2021, Paper 3 Higher, Q7(c) (2 marks): Scientists have discovered six disease-resistant Tasmanian devils in the population. Initially scientists did not know if this resistance was hereditary. Sugges
  42. November 2021, Paper 4 Higher, Q4(a) (1 mark): Describe what evidence her genome would have contained to show that she was female. [1]
  43. November 2020, Paper 1 Foundation, Q2(a)(i) (2 marks): Which two words can be used to describe Jack’s genotype? Put a ring around the two correct answers. dominant heterozygous homozygous recessive [2]
  44. November 2020, Paper 1 Foundation, Q2(a)(ii) (1 mark): Jack’s friend is unable to roll their tongue. What will their genotype be? Tick (✓) one box. RR Rr rr [1]
  45. November 2020, Paper 1 Foundation, Q2(a)(iii) (3 marks): A male with the genotype Rr and a female with the genotype Rr have a baby. Complete the Punnett square to show how the male and female can have a baby that can
  46. November 2020, Paper 1 Foundation, Q5(d) (2 marks): A chicken’s sex is determined by genes located on the sex chromosomes. Chickens have two different sex chromosomes, Z and W. Male chickens are ZZ and female chi
  47. November 2020, Paper 2 Foundation, Q2(c) (2 marks): Fertilisation takes place. The male gamete has the sex chromosome Y. What sex chromosomes will the baby have, and what sex will it be? Sex chromosomes Sex [2]
  48. November 2020, Paper 3 Higher, Q12(b)(ii) (1 mark): Is this disease likely to be seen more often in males or females? Explain your answer. Use your knowledge of sex determination in your answer. [1]
  49. November 2020, Paper 4 Higher, Q5(a) (2 marks): The allele that causes the disease is dominant. The other allele is recessive. A couple are planning to have a baby. • The female’s genotype is heterozygous dom
  50. November 2020, Paper 4 Higher, Q5(b) (2 marks): Give two reasons why a Punnett square cannot be used to predict most of a person’s features. 1 2 [2]
  51. June 2019, Paper 2 Foundation, Q5(b)(i) (1 mark): What is the phenotype of a person who has the alleles FF? [1]
  52. June 2019, Paper 2 Foundation, Q5(b)(ii) (1 mark): What is the phenotype of a person who has the alleles Ff? [1]
  53. June 2019, Paper 2 Foundation, Q5(b)(iii) (1 mark): What is the genotype of a person who has cystic fibrosis? [1]
  54. June 2019, Paper 2 Foundation, Q5(c)(i) (1 mark): What proportion of their offspring is likely to have the allele combination FF? in every [1]
  55. June 2019, Paper 2 Foundation, Q5(c)(ii) (2 marks): What percentage of their offspring is likely to have the allele combination Ff? Percentage = % [2]
  56. June 2019, Paper 2 Foundation, Q5(c)(iii) (2 marks): What is the probability that any one of their offspring will have cystic fibrosis? Probability = [2]
  57. June 2019, Paper 2 Foundation, Q5(d) (6 marks): Cystic fibrosis is a disease caused by a person’s DNA. (d)* A different couple is also thinking about having a baby. • The woman has had a genetic test. It show
  58. June 2019, Paper 3 Higher, Q11(a)(i) (2 marks): Use the letter F to write down the genotypes for a horse with the following coat colours. Solid coloured Frame patterned [2]
  59. June 2019, Paper 3 Higher, Q11(a)(ii) (4 marks): Lethal white syndrome (LWS) is a genetic disorder found in these horses. Foals born to these horses have all white or nearly white coats and blue eyes and appea
  60. June 2019, Paper 4 Higher, Q6(c)(i) (5 marks): Use the information to explain why sickle-cell disease is common in regions in which malaria is widespread. [5]
  61. June 2018, Paper 1 Foundation, Q3(a)(i) (1 mark): Jack is homozygous for this gene. What is Jack’s genotype? Tick (3) one box. TT Tt tT tt [1]
  62. June 2018, Paper 1 Foundation, Q3(a)(ii) (2 marks): Jack wants to know if any of his children will be able to taste the bitter substance. Nina has the genotype tt. Complete the Punnett square to show the possible
  63. June 2018, Paper 1 Foundation, Q3(a)(iii) (1 mark): What is the probability that any children born will be able to taste the bitter substance. Probability = [1]
  64. June 2018, Paper 1 Foundation, Q3(a)(iv) (2 marks): Jack and Nina have two children, one boy and one girl. Describe how sex is determined in humans. [2]
  65. June 2018, Paper 3 Higher, Q7(a)(i) (3 marks): Complete the table to show the genotype of each individual. Individual Genotype Jack Nina Mia [3]
  66. June 2018, Paper 3 Higher, Q7(a)(ii) (2 marks): Jack and Nina decide to have another child. What is the probability that the second child will have dimples? Use the Punnett square to show your working. Probab
  67. June 2018, Paper 3 Higher, Q7(b) (1 mark): Scientists consider this trait an ‘irregular’ dominant trait. This is because sometimes a person can have dimples but their children do not. What could be respo

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