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Synapses: OCR A‑Level Biology A questions

OCR A-Level Biology A past-paper questions on 5.1.3.4 Synapses, 2016–2025, with mark schemes and examiner’s reports where available.

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1,983 questions

  1. Q3(c)(ii)

    June 2025 · Paper 3

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  2. Q18(a)(i)

    June 2023 · Paper 1

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  3. Q18(a)(ii)

    June 2023 · Paper 1

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  4. Q14

    November 2020 · Paper 1

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  5. Q15

    November 2020 · Paper 1

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  6. Q18(b)(ii)

    November 2020 · Paper 1

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  7. Q11

    June 2019 · Paper 1

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  8. Q14

    June 2018 · Paper 1

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  9. Q5(b)(ii)

    June 2017 · Paper 3

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All 9 questions on Synapses, as a list
  1. June 2025, Paper 3, Q3(c)(ii) (2 marks): Explain how the binding of antibodies to acetylcholine receptors in the neuromuscular junction reduces the rate at which Ca2+ ions bind to troponin. [2]
  2. June 2023, Paper 1, Q18(a)(i) (1 mark): State the name given to the region labelled B. [1]
  3. June 2023, Paper 1, Q18(a)(ii) (1 mark): Identify whether structure A or structure C is the first neurone in the pathway. Use one piece of evidence visible in the electron micrograph to explain your ch
  4. November 2020, Paper 1, Q14 (1 mark): Which of the following statements, A to D, describes events occurring at a synapse? A Acetylcholine is broken down by enzymes so that it can bind to structure K
  5. November 2020, Paper 1, Q15 (1 mark): GABA is a neurotransmitter. GABA reduces the number of action potentials in the postsynaptic neurone by opening chloride ion channels in the post-synaptic membr
  6. November 2020, Paper 1, Q18(b)(ii) (4 marks): The sensory neurone was stimulated electrically and the FURA-2 fluorescence in the synaptic bulb was measured. At the same time, an electrode recorded the membr
  7. June 2019, Paper 1, Q11 (1 mark): The image below shows a synaptic bulb. I H J K Which of the following rows, A to D, correctly names the parts labelled H to J in the image? H I J K vesicle cont
  8. June 2018, Paper 1, Q14 (1 mark): The table below shows the membrane potentials of different neurones at a cholinergic synapse. The data were recorded on five separate occasions, as shown in the
  9. June 2017, Paper 3, Q5(b)(ii) (2 marks): Multiple sclerosis and Guillain–Barré syndrome both cause muscle weakness and loss of muscle function. Suggest and describe how the function of neuromuscular ju

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