Excretion as an example of homeostatic control: OCR A‑Level Biology A questions
Every OCR A-Level Biology A exam question on 5.1.2 Excretion as an example of homeostatic control, 2016–2025, with its mark scheme and examiner’s report.
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Q18(a)(i)
The whole paper ↗![June 2024 Paper 1, question 18(a)(i): State one other type of drug on the list of banned substances that can be detected in urine samples. [1]](https://pub-e8a9dbab8e2a4d089f52b2a45e0d0b50.r2.dev/bank/h42001-jun24-18-ai-qp.webp?v=3)
Q18(a)(ii)
The whole paper ↗![June 2024 Paper 1, question 18(a)(ii): Furosemide can also be misused by jockeys or boxers who need to be below a certain weight. Explain how a diuretic could help to reduce weight. [2]](https://pub-e8a9dbab8e2a4d089f52b2a45e0d0b50.r2.dev/bank/h42001-jun24-18-aii-qp.webp?v=3)
Q18(a)(iii)
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Q18(b)(i)
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Q18(b)(ii)
The whole paper ↗![June 2024 Paper 1, question 18(b)(ii): Give one other application of urine analysis in diagnosis. State the substance measured and the corresponding medical condition. Substance Medical condition [1]](https://pub-e8a9dbab8e2a4d089f52b2a45e0d0b50.r2.dev/bank/h42001-jun24-18-bii-qp.webp?v=3)
Q18(d)
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Q16(d)
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Q19(a)
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Q19(b)(i)
The whole paper ↗![June 2023 Paper 1, question 19(b)(i): Fig. 19.1 is a drawing of a longitudinal section of a kidney. Fig. 19.1 T U V Identify the parts of the kidney labelled T, U and V. T U V [3]](https://pub-e8a9dbab8e2a4d089f52b2a45e0d0b50.r2.dev/bank/h42001-jun23-19-bi-qp.webp?v=3)
Q19(b)(ii)
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Q19(c)(i)
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Q19(c)(ii)
The whole paper ↗![June 2023 Paper 1, question 19(c)(ii): Fig. 19.3 shows an increasing solute concentration. Outline the processes in the loop of Henle that cause the solute concentration to increase. [3]](https://pub-e8a9dbab8e2a4d089f52b2a45e0d0b50.r2.dev/bank/h42001-jun23-19-cii-qp.webp?v=3)


Q18(a)(i)
The whole paper ↗![November 2021 Paper 1, question 18(a)(i): Identify the structures labelled N and O in Fig. 18.1. N O [2]](https://pub-e8a9dbab8e2a4d089f52b2a45e0d0b50.r2.dev/bank/h42001-nov21-18-ai-qp.webp?v=3)
Q18(a)(ii)
The whole paper ↗![November 2021 Paper 1, question 18(a)(ii): The walls of the structure labelled M in Fig. 18.1 are lined with cells. Suggest and explain how these cells are adapted to carry out their function. [2]](https://pub-e8a9dbab8e2a4d089f52b2a45e0d0b50.r2.dev/bank/h42001-nov21-18-aii-qp.webp?v=3)
Q1(a)
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All 44 questions on Excretion as an example of homeostatic control, as a list
- June 2024, Paper 1, Q10 (1 mark): The diagram shows part of a liver lobule. F E G H I Which statement about liver function is correct? A Blood flows from I towards G. B H carries blood arriving
- June 2024, Paper 1, Q11 (1 mark): The photomicrograph shows a stained section of liver tissue. J What is the structure labelled J? A Hepatic artery B Hepatic portal vein C Hepatic vein D Sinusoi
- June 2024, Paper 1, Q12 (1 mark): Which statement describes urea production in the liver? A Amino acids enter the ornithine cycle. B Ammonia and carbon dioxide combine to make urea in the Krebs
- June 2024, Paper 1, Q18(a)(i) (1 mark): State one other type of drug on the list of banned substances that can be detected in urine samples. [1]
- June 2024, Paper 1, Q18(a)(ii) (2 marks): Furosemide can also be misused by jockeys or boxers who need to be below a certain weight. Explain how a diuretic could help to reduce weight. [2]
- June 2024, Paper 1, Q18(a)(iii) (1 mark): Furosemide is a banned substance because it can be used as a masking agent, to hide the use of performance enhancing drugs. Suggest how furosemide could act as
- June 2024, Paper 1, Q18(b)(i) (1 mark): Bladder cancer can be diagnosed by surgical removal of a small piece of bladder tissue (a biopsy sample). State one advantage of urine analysis over a biopsy sa
- June 2024, Paper 1, Q18(b)(ii) (1 mark): Give one other application of urine analysis in diagnosis. State the substance measured and the corresponding medical condition. Substance Medical condition [1]
- June 2024, Paper 1, Q18(d) (6 marks): (d)* Describe the homeostatic mechanisms that regulate the water content of the blood by changing how much water is reabsorbed from the collecting duct. You do
- June 2023, Paper 1, Q16(d) (4 marks): Changes to kidney function during pregnancy can be confused with some diseases, such as chronic kidney disease or kidney failure. The estimated glomerular filtr
- June 2023, Paper 1, Q19(a) (2 marks): Which statements about excretion and homeostasis are true, and which are false? Tick (✓) one box in each row. Statement True False The liver, kidneys, lungs and
- June 2023, Paper 1, Q19(b)(i) (3 marks): Fig. 19.1 is a drawing of a longitudinal section of a kidney. Fig. 19.1 T U V Identify the parts of the kidney labelled T, U and V. T U V [3]
- June 2023, Paper 1, Q19(b)(ii) (2 marks): Fig. 19.2 is a photomicrograph of a cross-section of part of the kidney. Fig. 19.2 × 360 Using the letter T, U or V from Fig. 19.1, identify the part of the kid
- June 2023, Paper 1, Q19(c)(i) (3 marks): Complete the table using the most appropriate letter or letters, W to Z, to show which part(s) of the nephron correspond to each of the statements. Each letter
- June 2023, Paper 1, Q19(c)(ii) (3 marks): Fig. 19.3 shows an increasing solute concentration. Outline the processes in the loop of Henle that cause the solute concentration to increase. [3]
- November 2021, Paper 1, Q1 (1 mark): Which of the options is not a function of the liver? A production of urea in the ornithine cycle B removal of amino groups from amino acids C storage of excess
- November 2021, Paper 1, Q9 (1 mark): The figure shows the results of three pregnancy tests using test strips with mobile and fixed (immobilised) monoclonal antibodies that bind to human chorionic g
- November 2021, Paper 1, Q18(a)(i) (2 marks): Identify the structures labelled N and O in Fig. 18.1. N O [2]
- November 2021, Paper 1, Q18(a)(ii) (2 marks): The walls of the structure labelled M in Fig. 18.1 are lined with cells. Suggest and explain how these cells are adapted to carry out their function. [2]
- November 2020, Paper 3, Q1(a) (2 marks): A student dissected a kidney. Fig. 1.1 shows one half of the dissected kidney. Fig. 1.1 Draw a simple diagram of the kidney in Fig. 1.1 in the space below. On y
- November 2020, Paper 3, Q1(b)(i) (1 mark): State one function of the distal convoluted tubule. [1]
- November 2020, Paper 3, Q1(b)(ii) (1 mark): Describe the function of the structures labelled A in Fig. 1.2. [1]
- November 2020, Paper 3, Q1(b)(iii) (1 mark): Suggest which lumen, B or C, has the highest concentration of urea. Explain your answer. [1]
- November 2020, Paper 3, Q1(c) (6 marks): (c)* Water reabsorption in the kidney is controlled by the endocrine and nervous systems. Aldosterone and ADH are hormones that act on the kidney. Aldosterone c
- November 2020, Paper 3, Q1(d)(i) (1 mark): Suggest which of the diuretics, X, Y or Z, would be the most effective at reducing a person’s blood pressure. Explain your choice. diuretic explanation [1]
- November 2020, Paper 3, Q1(d)(ii) (1 mark): Suggest which of the diuretics, X, Y or Z, would be the most appropriate for use by a person with type II diabetes. Explain your choice. diuretic explanation [1
- November 2020, Paper 3, Q6(c) (2 marks): When old red blood cells are broken down, each haem group is converted to a molecule called bilirubin. Bilirubin passes through the digestive system. Bilirubin
- June 2019, Paper 1, Q12 (1 mark): Damage to the hypothalamus results in lower water potential of the blood. Which of the following, A to D, explains these observations? A ADH release increases t
- June 2019, Paper 1, Q19(c)(i) (3 marks): Calculate the change in the number of samples testing positive for testosterone between 1988 and 1991. number of samples = [3]
- June 2019, Paper 1, Q19(c)(ii) (6 marks): Resistance training with weights can increase muscle mass in the body. It can also lead to vascularisation, where blood vessels become more visible through the
- June 2018, Paper 1, Q10 (1 mark): One treatment for thyroid cancer is radioactive iodine. The radioisotope I131 is used. The thyroid gland absorbs any iodine that enters the body, so the radioac
- June 2018, Paper 1, Q23(a) (3 marks): A student looked at slides of different tissues under a light microscope. The four viewed images are labelled W, X, Y and Z in Fig. 23.1, on the insert. Identif
- June 2018, Paper 3, Q6(a) (6 marks): The process of ultrafiltration in the kidney shares similarities with the formation of tissue fluid. (a)* Describe the similarities and differences between ultr
- June 2018, Paper 3, Q6(b)(i) (4 marks): Suggest two characteristics of a patient that must be taken into account when using this GFR measurement to diagnose kidney damage. Explain why each characteris
- June 2018, Paper 3, Q6(b)(ii) (1 mark): If kidney damage is suspected, the patient’s urine is likely to be tested for the protein albumin. Explain why the presence of albumin in the urine indicates ki
- June 2017, Paper 1, Q6 (1 mark): Patients with kidney failure can be treated in different ways. Which of the following statements describes a feature of peritoneal dialysis? 1 Urea and mineral
- June 2017, Paper 1, Q9 (1 mark): The hormone hCG can be detected in urine using pregnancy tests. Which of the following properties of the hormone hCG allows it to be detected in urine? A hCG is
- June 2017, Paper 1, Q12 (1 mark): The image below shows the structure of the nucleotide base guanine. O N NH N NH2 N H Bird droppings are known as guano because they contain a high proportion of
- June 2017, Paper 1, Q17(a)(i) (2 marks): Calculate the order of magnitude by which concentration of copeptin in the faeces is higher than the concentration of C-reactive protein in the saliva. Show you
- June 2017, Paper 1, Q17(a)(ii) (2 marks): Suggest why blood and faeces have the highest concentrations of C-reactive protein and copeptin. [2]
- June 2017, Paper 1, Q22(a)(i) (1 mark): Which letter identifies the region with the highest hydrostatic pressure? [1]
- June 2017, Paper 1, Q22(a)(ii) (1 mark): Which two letters identify regions that do not contain plasma proteins? [1]
- June 2017, Paper 1, Q22(b)(i) (3 marks): Using this information and your own knowledge, compare the processes occurring in the proximal and distal convoluted tubules. [3]
- June 2017, Paper 1, Q22(b)(ii) (2 marks): Nephrogenic diabetes insipidus is a disease of the kidney that affects the regulation of water potential in the blood. One cause is lithium poisoning. Lithium i
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