Transcription factors and hormones: Edexcel International A Level Biology questions
Edexcel International A Level Biology past-paper questions on 7.5.1 Transcription factors and hormones, 2019–2025, with mark schemes and examiner’s reports where available.
Paper
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Calculations
Q7(a)(ii)
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Q5(d)(i)
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Q2(b)(i)
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Q2(b)(ii)
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Q1(c)
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Q8(c)
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Q1(b)
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Q4(c)
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Q8(d)
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Q6(c)
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Q8(g)
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Q7(b)(i)
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All 12 questions on Transcription factors and hormones, as a list
- June 2025, Unit 5, Q7(a)(ii) (3 marks): Growth hormone is a peptide hormone that stimulates the synthesis of protein in muscle. Explain how GH stimulates the synthesis of protein in muscle. (3)
- January 2025, Unit 5, Q5(d)(i) (1 mark): Give one reason why there is no bar on the graph for an insulin concentration at 0 pmol dm–3. (1)
- October 2024, Unit 5, Q2(b)(i) (3 marks): Describe three conclusions that can be drawn from this investigation. (3)
- October 2024, Unit 5, Q2(b)(ii) (3 marks): Describe how steroid hormones regulate gene transcription. (3)
- October 2024, Unit 6, Q1(c) (3 marks): Describe how gibberellin increases amylase synthesis. (3)
- January 2024, Unit 5, Q8(c) (4 marks): Testosterone is a steroid hormone. Describe how reduced production of testosterone in the male testes can result in reduced muscle protein (paragraph 5). (4)
- October 2023, Unit 5, Q1(b) (3 marks): Describe how genes can be switched off by transcription factors. (3)
- January 2023, Unit 5, Q4(c) (4 marks): Oestrogen stimulates some types of breast cancer to proliferate. Oestrogen is a steroid hormone found in mammals. Oestrogen affects up to 100 different genes. E
- January 2022, Unit 5, Q8(d) (3 marks): Suggest how electrophilic species (ES) of free radicals could be “involved in the modulation of gene expression” (paragraph 6). (3)
- October 2021, Unit 5, Q6(c) (3 marks): Explain how cytokine genes can be expressed in an activated T lymphocyte. (3)
- June 2021, Unit 5, Q8(g) (2 marks): Suggest how myostatin might act as a negative regulator of muscle growth (paragraph 13). (2)
- January 2021, Unit 5, Q7(b)(i) (2 marks): Explain how transcription factors are involved in the synthesis of dopamine. (2)
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