plumiOxidative phosphorylation: Edexcel International A Level Biology questions
Edexcel International A Level Biology past-paper questions on 7.1.4 Oxidative phosphorylation, 2019–2025, with mark schemes and examiner’s reports where available.
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Q2(a)(i)
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All 29 questions on Oxidative phosphorylation, as a list
- June 2025, Unit 5, Q2(a)(i) (1 mark): Name a structure formed by the folding of the inner mitochondrial membrane. (1)
- June 2025, Unit 5, Q2(a)(ii) (1 mark): Which is a role of the inner mitochondrial membrane? (1) A to convert glucose to pyruvate B to phosphorylate ADP C to produce glucose from carbon dioxide D to t
- June 2025, Unit 5, Q2(b) (3 marks): Describe how reduced NAD is involved in the synthesis of ATP inside a mitochondrion. (3)
- June 2025, Unit 5, Q2(c)(i) (1 mark): Which is the role of oxygen molecules in mitochondria? (1) A to accept electrons B to donate electrons C to donate hydrogen ions D to form carbon dioxide
- June 2025, Unit 5, Q2(c)(ii) (1 mark): Which part of a mitochondrion contains the electron transport chain (ETC)? (1) A inner mitochondrial membrane B mitochondrial matrix C outer mitochondrial membr
- January 2025, Unit 5, Q7(b)(i) (1 mark): Which describes how ATP is synthesised by chemiosmosis? (1) A hydrogen ions are pumped from the matrix to the intermembrane space through ATP synthase B hydroge
- January 2025, Unit 5, Q7(b)(ii) (1 mark): Amytal is a drug that inhibits the electron transport chain in respiration. Which row of the table shows the changes caused by amytal when it is present in a ce
- June 2024, Unit 5, Q6(b) (4 marks): The photograph shows a coyote. (Source: © Shaun Cunningham/Alamy Stock Photo) Some coyotes have been poisoned with cyanide to prevent them from killing the live
- June 2024, Unit 6, Q1(a)(i) (1 mark): State the location in the mitochondria where oxidative phosphorylation takes place. (1)
- June 2024, Unit 6, Q1(a)(ii) (1 mark): Name one molecule that carries hydrogen for use in oxidative phosphorylation. (1)
- January 2024, Unit 5, Q8(g) (3 marks): Explain why aerobic exercise increases mitochondrial density and activity (paragraph 9). (3)
- June 2023, Unit 5, Q2(a)(i) (1 mark): Where is the site of the electron transport chain? (1) A cytoplasm B inner mitochondrial membrane C mitochondrial matrix D outer mitochondrial membrane
- June 2023, Unit 5, Q2(a)(iii) (2 marks): Describe the role of reduced NAD in aerobic respiration. (2)
- June 2023, Unit 5, Q2(b)(i) (3 marks): Carbon monoxide binds to the haem group of haemoglobin. Explain how carbon monoxide will affect the production of ATP. (3)
- January 2023, Unit 5, Q5(a) (1 mark): How is water formed during aerobic respiration? (1) A reduction of carbon B reduction of oxygen C phosphorylation of ADP D phosphorylation of glucose
- January 2023, Unit 5, Q8(a) (3 marks): Suggest why there is a relationship between the ageing process and neurodegeneration (paragraphs 1 and 2). (3)
- January 2023, Unit 5, Q8(b) (3 marks): Describe how energy released from glucose is used in oxidative phosphorylation (paragraph 2). (3)
- January 2023, Unit 5, Q8(c) (3 marks): Explain how free radicals (reactive oxygen species, ROS) can cause damage to mitochondrial DNA (paragraphs 2 and 4). (3)
- January 2023, Unit 5, Q8(f) (2 marks): Explain why synaptic mitochondria are more susceptible to ageing than the mitochondria found in other parts of a neurone (paragraph 9). (2)
- January 2023, Unit 5, Q8(g) (2 marks): Explain why the mitochondrial genome is essential for oxidative phosphorylation (paragraph 10). (2)
- October 2022, Unit 5, Q1(a)(i) (1 mark): How many of these statements about the inner membrane of a mitochondrion are correct? (1) • it is folded (has cristae) • it is the location of ATP synthase • it
- October 2022, Unit 5, Q1(b) (2 marks): Describe how chemiosmosis is involved in the synthesis of ATP. (2)
- October 2022, Unit 5, Q1(c) (1 mark): A culture containing respiring cells was supplied with radioactive oxygen molecules. Which will be the first substance to contain radioactive oxygen atoms? (1)
- January 2022, Unit 5, Q1(b) (3 marks): Describe how ATP is synthesised by oxidative phosphorylation in the mitochondrion. (3)
- October 2021, Unit 5, Q5(a)(iii) (1 mark): Hydramethylnon is an insecticide that is used to treat termite infestations. Hydramethylnon inhibits the electron transport chain. Which row of the table shows
- June 2021, Unit 5, Q1(a) (3 marks): One product of all three stages shown in the table is ATP (adenosine triphosphate). Complete the table to show one other product of each stage. (3) Stage One ot
- June 2021, Unit 5, Q1(d) (2 marks): Describe how oxygen is involved in the production of ATP on the cristae in the mitochondria. (2)
- January 2021, Unit 5, Q4(b) (6 marks): Inherited mitochondrial diseases affect muscle function. The diagram shows the electron transport chain in a mitochondrion. reduced oxidised TMPD TMPD cytochrom
- October 2020, Unit 5, Q1(b)(iii) (5 marks): Describe the role of chemiosmosis in the synthesis of ATP. (5)
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