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One gene, more than one protein: Edexcel International A Level Biology questions

Edexcel International A Level Biology past-paper questions on 3.5.3 One gene, more than one protein, 2019–2025, with mark schemes and examiner’s reports where available.

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  1. Q6(b)

    June 2025 · AS Unit 2

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  2. Q7(a)

    January 2025 · AS Unit 2

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  3. Q5(b)

    June 2024 · AS Unit 2

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  4. Q2(c)

    June 2023 · AS Unit 2

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  5. Q7(b)

    June 2023 · Unit 5

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  6. Q8(b)

    January 2023 · AS Unit 2

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  7. Q3(b)

    January 2022 · AS Unit 2

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  8. Q6(e)

    October 2021 · Unit 5

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  9. Q7(c)

    October 2020 · AS Unit 2

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All 9 questions on One gene, more than one protein, as a list
  1. June 2025, AS Unit 2, Q6(b) (4 marks): One gene from this starfish pluripotent stem cell produces pre‑mRNA. The diagram shows how three different strands of active mRNA are produced from one strand o
  2. January 2025, AS Unit 2, Q7(a) (3 marks): Molecules of pre‑mRNA are produced by transcription of active genes. These molecules undergo post‑transcriptional changes to form active mRNA. Describe how post
  3. June 2024, AS Unit 2, Q5(b) (4 marks): The development of an embryo into either a female or a male fruit fly is determined by two different proteins. The female specific Dsx-F protein leads to the de
  4. June 2023, AS Unit 2, Q2(c) (3 marks): One gene can give rise to more than one type of protein through post‑transcriptional changes to the mRNA. One of these changes is the removal of introns. Explai
  5. June 2023, Unit 5, Q7(b) (4 marks): There are 14 different serotonin receptors found in the human nervous system. Three different genes are used to produce these receptors. Explain how three genes
  6. January 2023, AS Unit 2, Q8(b) (2 marks): One treatment for AD is mRNA therapy. In this therapy, people are given the mRNA molecules needed for arginase production. The mRNA used in this therapy is acti
  7. January 2022, AS Unit 2, Q3(b) (4 marks): Active mRNA is formed after post‑transcriptional modification of pre‑mRNA. The structure of pre‑mRNA produced from transcription is different from the structure
  8. October 2021, Unit 5, Q6(e) (3 marks): CD45 is a protein found on the surface of lymphocytes. Different forms of the CD45 protein are found on the surface of different lymphocytes. Describe how diffe
  9. October 2020, AS Unit 2, Q7(c) (5 marks): More than one type of protein can be synthesised from the RNA produced from one gene. The diagram shows parts of this process. DNA P Q R S T U V W X pre-mRNA P

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