plumiDrug testing: Edexcel International A Level Biology questions
Edexcel International A Level Biology past-paper questions on 4.3.3 Drug testing, 2019–2025, with mark schemes and examiner’s reports where available.
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Q7(c)(i)
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All 24 questions on Drug testing, as a list
- October 2024, AS Unit 2, Q7(c)(i) (1 mark): Which percentage of the initial group of patients were placed in group B? (1) A 8.3 % B 8.5 % C 49.5 % D 50.5 %
- October 2024, AS Unit 2, Q7(c)(ii) (1 mark): Suggest how this study could be carried out as a double-blind trial. Use the diagram to support your answer. (1)
- October 2024, AS Unit 2, Q7(c)(iii) (4 marks): The table shows the mean difference in circumference for the infected and non-infected legs at 5 and 10 days after treatment began. Mean difference in circumfer
- October 2024, Unit 5, Q8(h) (1 mark): Give one reason why a placebo was used in the donanemab trial (Paragraph 33). (1)
- January 2024, AS Unit 2, Q4(c) (5 marks): The photograph shows part of a Madonna lily plant (L. candidum). (Source: © Zoonar GmbH/Alamy Stock Photo) An extract made from L. candidum has been used in tra
- October 2023, AS Unit 2, Q6(b)(i) (1 mark): Which of the following describes the purpose of the current pain‑relieving drug in stage II of the drug trial? (1) A control B digitalis C placebo D solvent
- October 2023, AS Unit 2, Q6(b)(ii) (4 marks): Describe the processes that would have occurred before and after stage II in this tetrodoxin drug trial. (4)
- October 2023, AS Unit 2, Q6(c) (4 marks): The graph shows the duration of pain relief using both tetrodoxin and the current pain‑relieving drug in stage II of this drug trial. Key Tetrodoxin Current pai
- June 2023, AS Unit 2, Q7(c)(i) (3 marks): Explain the purpose of the gel used in these treatments. (3)
- June 2023, AS Unit 2, Q7(c)(ii) (4 marks): Comment on the results of this investigation. (4)
- January 2023, AS Unit 2, Q6(b)(i) (4 marks): Evaluate the results of this investigation. (4)
- January 2023, AS Unit 2, Q6(b)(ii) (3 marks): Drug A was then used in a three-phase drug trial. Compare and contrast phases II and III in a contemporary drug trial using drug A. (3)
- October 2022, Unit 4, Q6(a) (3 marks): Drug ATD was recently approved for the treatment of Alzheimer’s disease. Describe the information that had to be collected by scientists before this drug could
- January 2022, AS Unit 2, Q5(d) (3 marks): Drugs containing these chemicals must be tested for safety before they can be approved and used to treat humans. Three‑phase testing can be used to check for th
- January 2022, AS Unit 3, Q1(c) (3 marks): Plant extracts can be used to make new drugs for the treatment of infections. In trials to test these drugs, placebos and double-blind trials are used. Explain
- October 2021, AS Unit 1, Q6(a)(i) (2 marks): Comment on the design of this clinical trial. (2)
- October 2021, AS Unit 1, Q6(a)(ii) (2 marks): Each patient was given 2.5 mg of the drug per kg of body mass, once a month. The drug is available as a solution with a concentration of 189 mg cm−3. Calculate
- October 2021, AS Unit 1, Q6(a)(iii) (2 marks): Nausea was experienced by 27% of the patients receiving this drug. Calculate the number of patients who experienced nausea. (2) Answer
- October 2021, AS Unit 2, Q4(b)(i) (1 mark): Which of the following scientists tested the effectiveness of digitalis soup? (1) A Adolf Fick B Matthew Meselson and Franklin Stahl C Godfrey Hardy and Wilhelm
- October 2021, AS Unit 2, Q4(b)(ii) (2 marks): Curacin A is being developed as a drug to treat some colon and kidney cancers in humans. Suggest how a suitable dose for cancer treatment would be determined in
- October 2021, AS Unit 2, Q4(b)(iii) (4 marks): Describe how a double-blind clinical trial would be performed with this cancer drug. (4)
- June 2021, AS Unit 2, Q8(b)(iii) (2 marks): The bacterium Pseudomonas aeruginosa causes lung infections in humans. Describe how a drug containing flavonoids could be tested in a stage II drug trial. (2)
- October 2020, AS Unit 2, Q5(c) (2 marks): Anticancer drugs have to undergo double‑blind trials before they are used to treat patients. Describe how a placebo is used in a double‑blind trial. (2)
- June 2019, AS Unit 2, Q5(b)(ii) (6 marks): The ironwood tree has wood containing chemical compounds called naphthoquinones. These compounds have antibacterial properties. Scientists are investigating whe
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