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Bacteria and viruses compared: Edexcel International A Level Biology questions

Edexcel International A Level Biology past-paper questions on 6.2.1 Bacteria and viruses compared, 2019–2025, with mark schemes and examiner’s reports where available.

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  1. Q9(a)(i)

    June 2025 · Unit 4

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  2. Q9(a)(ii)

    June 2025 · Unit 4

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  3. Q9(a)

    January 2025 · Unit 4

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  4. The start of question 7

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  5. Q5(b)(i)

    June 2024 · Unit 4

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  6. Q5(b)(ii)

    June 2024 · Unit 4

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  7. Q5(b)(iii)

    June 2024 · Unit 4

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  8. Q5(b)(iv)

    June 2024 · Unit 4

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  9. Q7(e)

    October 2023 · Unit 4

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  10. Q3(a)

    January 2023 · Unit 4

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  11. Q8(a)(ii)

    January 2023 · Unit 4

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  12. Q8(c)

    January 2023 · Unit 4

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  13. Q2(a)

    October 2022 · Unit 4

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  14. Q2(b)(i)

    October 2022 · Unit 4

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  15. Q2(b)(ii)

    October 2022 · Unit 4

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  16. Q6(a)(i)

    June 2022 · Unit 4

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  17. Q6(a)(ii)

    June 2022 · Unit 4

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  18. Q6(a)(iii)

    June 2022 · Unit 4

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  19. Q3(b)(iii)

    January 2022 · Unit 4

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  20. Q4(a)

    January 2022 · Unit 4

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All 36 questions on Bacteria and viruses compared, as a list
  1. June 2025, Unit 4, Q9(a)(i) (1 mark): Calculate how many tonnes of rice are lost if 20% of the harvest is lost. Give your answer in standard form. (1) Answer tonnes
  2. June 2025, Unit 4, Q9(a)(ii) (2 marks): Explain why it is important to identify rice plants infected with RYMV as early as possible. (2)
  3. January 2025, Unit 4, Q9(a) (6 marks): Explain how retroviruses introduce ERVs into human cells and how the ancient ERVs can be transmitted to offspring in families. (6)
  4. October 2024, Unit 4, Q7(a) (4 marks): Explain how infection with these bacteria results in the death of the leaf cells and eventually the whole plant. (4)
  5. June 2024, Unit 4, Q5(b)(i) (1 mark): Which of the following statements are true? (1) 1 Ebola virus has the same type of genetic material as herpes simplex virus 2 Both Ebola virus and human immun
  6. June 2024, Unit 4, Q5(b)(ii) (1 mark): State the function of the envelope proteins. (1)
  7. June 2024, Unit 4, Q5(b)(iii) (2 marks): Explain why the herpes simplex virus has to be modified before it can be used to infect cancer cells. (2)
  8. June 2024, Unit 4, Q5(b)(iv) (2 marks): Explain how the infection of a cancer cell with herpes simplex virus can result in the death of this cell. (2)
  9. October 2023, Unit 4, Q7(e) (2 marks): In oncolytic virotherapy, viruses that destroy cancer cells are injected into the patient. Not all types of virus are suitable for this therapy. Suggest two fea
  10. January 2023, Unit 4, Q3(a) (1 mark): Viruses such as the vanilla mosaic virus damage the leaves of vanilla plants. The vanilla mosaic virus has a similar structure to tobacco mosaic virus (TMV). Wh
  11. January 2023, Unit 4, Q8(a)(ii) (3 marks): The diagram shows this polyprotein and the function of some of the individual proteins it contains. The arrows indicate where the individual proteins need to be
  12. January 2023, Unit 4, Q8(c) (2 marks): Another group of scientists infected the eggs of mosquitoes with Wolbachia bacteria. The Wolbachia do not harm the mosquitoes but compete with the virus so that
  13. October 2022, Unit 4, Q2(a) (3 marks): For each structure, put one cross in the appropriate box, in each row, to show which viruses have that structure. (3) Virus Structure both Ebola neither Ebola E
  14. October 2022, Unit 4, Q2(b)(i) (1 mark): Name the enzyme, found in some types of virus, that can synthesise DNA from an RNA template. (1)
  15. October 2022, Unit 4, Q2(b)(ii) (1 mark): Suggest why this DNA polymerase may be a target for drugs used to treat cancer. (1)
  16. June 2022, Unit 4, Q6(a)(i) (1 mark): Which structure is RNA? (1) A R B Q C S D T
  17. June 2022, Unit 4, Q6(a)(ii) (1 mark): How many of the following structures contain protein? • structure Q • structure R • structure S (1) A 0 B 1 C 2 D 3
  18. June 2022, Unit 4, Q6(a)(iii) (1 mark): Which virus has structure P and contains RNA? (1) A Ebola virus only B Ebola virus and tobacco mosaic virus (TMV) C Tobacco mosaic virus (TMV) only D Neither Eb
  19. January 2022, Unit 4, Q3(b)(iii) (2 marks): If a patient stops taking the antiretroviral drugs, the number of virus particles increases again. Suggest why this increase occurs. (2)
  20. January 2022, Unit 4, Q4(a) (1 mark): How many of the following statements are correct for λ phage? • the genetic material is DNA • the capsid structure is described as complex • the genetic materia
  21. January 2022, Unit 4, Q4(b) (2 marks): Describe the role of the λ phage J protein. Use the information in the diagram to support your answer. (2)
  22. January 2022, Unit 4, Q4(c)(i) (1 mark): Give one reason why sugars are important to E. coli. (1)
  23. October 2021, Unit 4, Q2(a)(i) (1 mark): The rabies virus has an envelope. Which of the following pairs of viruses have an envelope? (1) A Ebola virus and human immunodeficiency virus (HIV) B human imm
  24. October 2021, Unit 4, Q2(a)(ii) (1 mark): The structure of the rabies capsid is described as complex. Which of the following has a complex capsid structure? (1) A Ebola virus B human immunodeficiency vi
  25. October 2021, Unit 4, Q2(a)(iii) (1 mark): Rabies virus is an RNA virus. How many of the following viruses are RNA viruses? • Ebola virus • human immunodeficiency virus (HIV) lambda phage (λ phage) • • t
  26. October 2021, Unit 4, Q2(b)(ii) (2 marks): Explain why a positive RNA strand has to be made. (2)
  27. October 2021, Unit 4, Q2(c) (4 marks): Lemurs are found in Madagascar. It is thought that they might carry rabies viruses. The photograph shows a lemur. (Source: Caroline Wilcox) A person was bitten
  28. June 2021, Unit 4, Q8(b) (6 marks): Phage therapy was used to treat the Mycobacterium infection in this patient. Phages are viruses that target bacterial cells. The graph shows how the number of M
  29. January 2021, Unit 5, Q8(a) (2 marks): The Ebola virus can infect endothelial cells. Describe how this virus can cause internal bleeding (paragraph 1). (2)
  30. October 2020, Unit 4, Q5(a) (1 mark): Which virus can infect bacteria? (1) A Ebola virus B human immunodeficiency virus (HIV) C lambda phage (λ phage) D tobacco mosaic virus (TMV)
  31. October 2020, Unit 4, Q5(b)(iii) (2 marks): Lysins break down the cell wall of bacteria. Explain the role of lysins in the lytic cycle. (2)
  32. January 2020, Unit 4, Q5(a)(i) (2 marks): The viral genome (2)
  33. January 2020, Unit 4, Q5(a)(ii) (2 marks): The glycoproteins (2)
  34. January 2020, Unit 4, Q5(b) (2 marks): The enzyme RNA polymerase is involved in RNA transcription. Explain why the structure of the Ebola virus includes RNA polymerase. (2)
  35. January 2020, Unit 4, Q5(c) (2 marks): The proteins VP24 and VP40 are involved in virus assembly. State what is meant by the term virus assembly, using Ebola as an example. (2)
  36. January 2020, Unit 4, Q8(b)(i) (1 mark): The virus used in this procedure is modified so that it is not pathogenic. Which virus would be suitable to use in Step 2? (1) A Ebola virus B human immunodefic

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