Skip to content
Try on iPad

Monoclonal antibodies: AQA GCSE Biology questions

Every AQA GCSE Biology exam question on 4.3.2 Monoclonal antibodies, 2018–2025, with its mark scheme and examiner’s report.

Find questions1,505
Calculations

1,505 questions

  1. Q07.3

    June 2025 · Paper 1 Higher

    3 marks4.3.2 Monoclonal antibodies
    The whole paper ↗
    June 2025 Paper 1 Higher, question 07.3: Name the three types of cell in Figure 9. [3 marks] A B C

  2. Q07.4

    June 2025 · Paper 1 Higher

    1 mark4.3.2 Monoclonal antibodies
    The whole paper ↗
    June 2025 Paper 1 Higher, question 07.4: How is the mouse stimulated to produce cell type A? [1 mark]

  3. Q07.6

    June 2025 · Paper 1 Higher

    1 mark4.3.2 Monoclonal antibodies
    The whole paper ↗
    June 2025 Paper 1 Higher, question 07.6: Give one other use of monoclonal antibodies. Do not refer to pregnancy tests. [1 mark] The liver produces bile.

  4. Q04.4

    June 2023 · Paper 1 Higher

    1 mark4.3.2 Monoclonal antibodies
    The whole paper ↗
    June 2023 Paper 1 Higher, question 04.4: What type of cell is created when a mouse lymphocyte and a tumour cell combine? [1 mark] Tick () one box. Embryo Hybridoma Phagocyte Stem cell

  5. Q04.5

    June 2023 · Paper 1 Higher

    3 marks4.3.2 Monoclonal antibodies
    The whole paper ↗
    June 2023 Paper 1 Higher, question 04.5: Describe how scientists make monoclonal antibodies using the cell created when a mouse lymphocyte and a tumour cell combine. [3 marks]

  6. Q04.6

    June 2023 · Paper 1 Higher

    1 mark4.3.2 Monoclonal antibodies
    The whole paper ↗
    June 2023 Paper 1 Higher, question 04.6: What property makes a monoclonal antibody useful in detecting the presence of an anabolic steroid in urine? [1 mark] Tick () one box. A monoclonal antibody is

  7. Q04.7

    June 2023 · Paper 1 Higher

    1 mark4.3.2 Monoclonal antibodies
    The whole paper ↗
    June 2023 Paper 1 Higher, question 04.7: Suggest the purpose of the control area in the test strip. [1 mark]

  8. Q04.8

    June 2023 · Paper 1 Higher

    2 marks4.3.2 Monoclonal antibodies
    The whole paper ↗
    June 2023 Paper 1 Higher, question 04.8: Describe the evidence in Figure 6 that shows the test for athlete B has not worked. Suggest one reason why the test did not work. [2 marks] Evidence Reason

  9. Q04.9

    June 2023 · Paper 1 Higher

    1 mark4.3.2 Monoclonal antibodies
    The whole paper ↗
    June 2023 Paper 1 Higher, question 04.9: Which athlete has tested positive for anabolic steroids in their urine? [1 mark] Tick () one box. A B C D

  10. Q07.7

    June 2022 · Paper 1 Higher

    4 marks4.3.2 Monoclonal antibodies
    The whole paper ↗
    June 2022 Paper 1 Higher, question 07.7: Describe how the monoclonal antibody for HIV can be produced. [4 marks]

  11. Q07.8

    June 2022 · Paper 1 Higher

    3 marks4.3.2 Monoclonal antibodies
    The whole paper ↗
    June 2022 Paper 1 Higher, question 07.8: Figure 9 shows how HIV enters a human cell. Figure 9 Suggest how the monoclonal antibody for HIV helps to prevent a person infected with HIV developing AIDS. Us

  12. Q07.1

    November 2020 · Paper 1 Higher

    3 marks4.3.2 Monoclonal antibodies
    The whole paper ↗
    November 2020 Paper 1 Higher, question 07.1: Candida albicans lives in the throat of infected patients. A sample is taken from the throat of a patient with a suspected Candida albicans infection. The sampl

  13. Q07.4

    November 2020 · Paper 1 Higher

    1 mark4.3.2 Monoclonal antibodies4.3.1 Communicable diseases
    The whole paper ↗
    November 2020 Paper 1 Higher, question 07.4: Scientists have also used human lymphocytes to make mAbs to other pathogens and to some types of cancer cells. Suggest one reason why these new mAbs have been m

  14. Q05.3

    June 2018 · Paper 1 Higher

    4 marks4.3.2 Monoclonal antibodies
    The whole paper ↗
    June 2018 Paper 1 Higher, question 05.3: A farmer thinks a potato crop is infected with potato virus Y (PVY). The farmer obtains a monoclonal antibody test kit for PVY. To make the monoclonal antibodie

  15. Q11.1

    Specimen · Paper 1 Higher

    4.3.2 Monoclonal antibodies
    The whole paper ↗
    Specimen Paper 1 Higher, question 11.1: Which test strip shows a negative test result? [1 ma Tick one box. A B C D

  16. Q11.2

    Specimen · Paper 1 Higher

    4.3.2 Monoclonal antibodies
    The whole paper ↗
    Specimen Paper 1 Higher, question 11.2: Monoclonal antibodies are used for pregnancy testing. Give one other use of monoclonal antibodies. [1 ma 35

  17. Q11.3

    Specimen · Paper 1 Higher

    6 marks4.3.2 Monoclonal antibodies
    The whole paper ↗
    Specimen Paper 1 Higher, question 11.3: Figure 9 shows the parts of a pregnancy test strip. Figure 9 The pregnancy test strip will show a positive test result when a woman is pregnant. Explain how the
All 17 questions on Monoclonal antibodies, as a list
  1. June 2025, Paper 1 Higher, Q07.3 (3 marks): Name the three types of cell in Figure 9. [3 marks] A B C
  2. June 2025, Paper 1 Higher, Q07.4 (1 mark): How is the mouse stimulated to produce cell type A? [1 mark]
  3. June 2025, Paper 1 Higher, Q07.6 (1 mark): Give one other use of monoclonal antibodies. Do not refer to pregnancy tests. [1 mark] The liver produces bile.
  4. June 2023, Paper 1 Higher, Q04.4 (1 mark): What type of cell is created when a mouse lymphocyte and a tumour cell combine? [1 mark] Tick () one box. Embryo Hybridoma Phagocyte Stem cell
  5. June 2023, Paper 1 Higher, Q04.5 (3 marks): Describe how scientists make monoclonal antibodies using the cell created when a mouse lymphocyte and a tumour cell combine. [3 marks]
  6. June 2023, Paper 1 Higher, Q04.6 (1 mark): What property makes a monoclonal antibody useful in detecting the presence of an anabolic steroid in urine? [1 mark] Tick () one box. A monoclonal antibody is
  7. June 2023, Paper 1 Higher, Q04.7 (1 mark): Suggest the purpose of the control area in the test strip. [1 mark]
  8. June 2023, Paper 1 Higher, Q04.8 (2 marks): Describe the evidence in Figure 6 that shows the test for athlete B has not worked. Suggest one reason why the test did not work. [2 marks] Evidence Reason
  9. June 2023, Paper 1 Higher, Q04.9 (1 mark): Which athlete has tested positive for anabolic steroids in their urine? [1 mark] Tick () one box. A B C D
  10. June 2022, Paper 1 Higher, Q07.7 (4 marks): Describe how the monoclonal antibody for HIV can be produced. [4 marks]
  11. June 2022, Paper 1 Higher, Q07.8 (3 marks): Figure 9 shows how HIV enters a human cell. Figure 9 Suggest how the monoclonal antibody for HIV helps to prevent a person infected with HIV developing AIDS. Us
  12. November 2020, Paper 1 Higher, Q07.1 (3 marks): Candida albicans lives in the throat of infected patients. A sample is taken from the throat of a patient with a suspected Candida albicans infection. The sampl
  13. November 2020, Paper 1 Higher, Q07.4 (1 mark): Scientists have also used human lymphocytes to make mAbs to other pathogens and to some types of cancer cells. Suggest one reason why these new mAbs have been m
  14. June 2018, Paper 1 Higher, Q05.3 (4 marks): A farmer thinks a potato crop is infected with potato virus Y (PVY). The farmer obtains a monoclonal antibody test kit for PVY. To make the monoclonal antibodie
  15. Specimen, Paper 1 Higher, Q11.1: Which test strip shows a negative test result? [1 ma Tick one box. A B C D
  16. Specimen, Paper 1 Higher, Q11.2: Monoclonal antibodies are used for pregnancy testing. Give one other use of monoclonal antibodies. [1 ma 35
  17. Specimen, Paper 1 Higher, Q11.3 (6 marks): Figure 9 shows the parts of a pregnancy test strip. Figure 9 The pregnancy test strip will show a positive test result when a woman is pregnant. Explain how the

Questions, mark schemes and examiner’s reports are © AQA, from their published past papers. Plumi isn’t affiliated with any exam board. Want whole papers? Every AQA GCSE Biology paper.

Rather write your answers by hand on iPad? Plumi marks them against the same mark schemes.