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How do organisms protect themselves against pathogens?: OCR GCSE Combined Science B questions

Every OCR GCSE Combined Science B exam question on B2.2 How do organisms protect themselves against pathogens?, 2018–2025, with its mark scheme and examiner’s report.

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2,688 questions

  1. Q3(a)(i)

    June 2025 · Biology Paper 5 Higher

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    The start of question 3
  2. Q3(a)(ii)

    June 2025 · Biology Paper 5 Higher

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  3. Q3(a)(iii)

    June 2025 · Biology Paper 5 Higher

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  4. Q3(c)(ii)

    June 2025 · Biology Paper 5 Higher

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    The start of question 3
  5. Q1(a)(ii)

    June 2023 · Biology Paper 1 Foundation

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    The start of question 1
  6. Q1(b)

    June 2023 · Biology Paper 1 Foundation

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    The start of question 1
  7. Q1(c)

    June 2023 · Biology Paper 1 Foundation

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    The start of question 1
  8. Q1

    June 2023 · Combined Science Paper 4 Foundation

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  9. Q9(c)

    June 2023 · Biology Paper 5 Higher

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    The start of question 9
  10. Q11(b)

    November 2021 · Biology Paper 1 Foundation

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  11. Q1(b)

    November 2021 · Biology Paper 5 Higher

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  12. Q3(b)(i)

    November 2020 · Biology Paper 1 Foundation

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  13. Q6(b)

    November 2020 · Biology Paper 5 Higher

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  14. Q6(b)(i)

    June 2019 · Biology Paper 1 Foundation

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    The start of question 6
All 14 questions on How do organisms protect themselves against pathogens?, as a list
  1. June 2025, Biology Paper 5 Higher, Q3(a)(i) (3 marks): Complete the sentences to explain how immune system cells in the blood are adapted to fight infections. Use words from the list. antibodies antigens red blood c
  2. June 2025, Biology Paper 5 Higher, Q3(a)(ii) (1 mark): Antibodies are proteins. Which molecules are joined together to make a protein? Tick (✓) one box. Amino acids Fatty acids and glycerol Glucose Starch [1]
  3. June 2025, Biology Paper 5 Higher, Q3(a)(iii) (1 mark): What is the reagent used to test for proteins? Tick (✓) one box. Benedict’s solution Biuret solution Ethanol Iodine solution [1]
  4. June 2025, Biology Paper 5 Higher, Q3(c)(ii) (1 mark): Explain why a common communicable disease such as influenza can be much more dangerous for a person who is living with AIDS. [1]
  5. June 2023, Biology Paper 1 Foundation, Q1(a)(ii) (1 mark): Which system are white blood cells a part of? Tick (3) one box. Gas exchange system Immune system Nervous system [1]
  6. June 2023, Biology Paper 1 Foundation, Q1(b) (2 marks): The human body has different types of defences against pathogens. Draw lines to connect each type of defence with the correct example. Type of defence Example B
  7. June 2023, Biology Paper 1 Foundation, Q1(c) (2 marks): Beth has a cut on her finger. Platelets in Beth’s blood help to seal the cut so bacteria can’t get into it. Which two statements explain how her platelets do th
  8. June 2023, Combined Science Paper 4 Foundation, Q1 (3 marks): Pathogens can cause diseases in humans. Draw lines to connect each defence mechanism with the explanation of how it functions. Defence mechanism Explanation Clo
  9. June 2023, Biology Paper 5 Higher, Q9(c) (3 marks): All blood cells are made from stem cells in the bone marrow (soft tissue inside bones). Leukaemia is a type of cancer that disrupts this process. Having leukaem
  10. November 2021, Biology Paper 1 Foundation, Q11(b) (3 marks): Measles is caused by a virus. White blood cells help protect us against measles. Complete each sentence about how white blood cells protect us against measles.
  11. November 2021, Biology Paper 5 Higher, Q1(b) (3 marks): Measles is caused by a virus. White blood cells help protect us against measles. Complete each sentence about how white blood cells protect us against measles.
  12. November 2020, Biology Paper 1 Foundation, Q3(b)(i) (2 marks): Salmonella bacteria can cause food poisoning. Fig. 3.1 shows some of the body’s natural defences against disease. Which two natural defences protect us against
  13. November 2020, Biology Paper 5 Higher, Q6(b) (2 marks): Salmonella bacteria can cause food poisoning. When Salmonella bacteria is swallowed, it must pass through the stomach to get to the small intestine where the Sa
  14. June 2019, Biology Paper 1 Foundation, Q6(b)(i) (2 marks): Vaccination causes white blood cells in the body to make antibodies against the pathogen. How else do white blood cells protect against pathogens? Tick (✓) two

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