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Coordination and control – the endocrine system: OCR GCSE Combined Science A questions

Every OCR GCSE Combined Science A exam question on B3.2 Coordination and control – the endocrine system, 2018–2025, with its mark scheme and examiner’s report.

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3,411 questions

  1. Q9

    June 2025 · Biology Paper 1 Foundation

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  2. Q14(a)

    June 2025 · Biology Paper 1 Foundation

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  3. Q14(b)

    June 2025 · Biology Paper 1 Foundation

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  4. Q1

    June 2025 · Biology Paper 7 Higher

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  5. Q16(b)

    June 2025 · Biology Paper 7 Higher

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  6. Q16(c)

    June 2025 · Biology Paper 7 Higher

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  7. Q11(d)(i)

    June 2024 · Biology Paper 1 Foundation

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  8. Q11(d)(ii)

    June 2024 · Biology Paper 1 Foundation

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  9. Q14(b)(i)

    June 2024 · Biology Paper 7 Higher

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  10. Q14(b)(ii)

    June 2024 · Biology Paper 7 Higher

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  11. Q14(c)

    June 2024 · Biology Paper 7 Higher

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  12. Q8

    June 2023 · Biology Paper 1 Foundation

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  13. Q10

    June 2023 · Biology Paper 1 Foundation

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  14. Q12(c)

    June 2023 · Biology Paper 1 Foundation

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  15. Q2

    June 2023 · Biology Paper 7 Higher

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  16. Q10

    June 2023 · Biology Paper 7 Higher

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  17. Q13(b)

    June 2023 · Biology Paper 7 Higher

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  18. Q5

    June 2022 · Biology Paper 1 Foundation

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  19. Q11(d)

    June 2022 · Biology Paper 1 Foundation

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All 46 questions on Coordination and control – the endocrine system, as a list
  1. June 2025, Biology Paper 1 Foundation, Q9 (1 mark): What is the main source of testosterone in the human body? A Adrenal glands B Pancreas C Pituitary gland D Testes Your answer [1]
  2. June 2025, Biology Paper 1 Foundation, Q14(a) (2 marks): Draw three lines to connect each hormone and its role in the menstrual cycle. Hormone Role in the menstrual cycle FSH causes an egg to mature in the ovary Oestr
  3. June 2025, Biology Paper 1 Foundation, Q14(b) (6 marks): Hormones are important in the menstrual cycle. (b)* Contraception is used to prevent pregnancy. The effectiveness of a contraceptive depends on the method and i
  4. June 2025, Biology Paper 7 Higher, Q1 (1 mark): What is the main source of testosterone in the human body? A Adrenal glands B Pancreas C Pituitary gland D Testes Your answer [1]
  5. June 2025, Biology Paper 7 Higher, Q16(b) (3 marks): Hormones are responsible for coordinating longer lasting responses. Describe how low thyroxine levels would stimulate a response by the body. Use the words in t
  6. June 2025, Biology Paper 7 Higher, Q16(c) (6 marks): Animals produce coordinated responses when there are changes to their internal or external environments. (c)* IVF is a treatment some people use when they have
  7. June 2024, Biology Paper 1 Foundation, Q11(d)(i) (1 mark): Which day of the cycle does hormone X reach its peak? [1]
  8. June 2024, Biology Paper 1 Foundation, Q11(d)(ii) (2 marks): Draw a line from each hormone to its correct name. insulin Hormone X oestrogen Hormone Y progesterone testosterone [2]
  9. June 2024, Biology Paper 7 Higher, Q14(b)(i) (1 mark): Which endocrine gland releases thyroxine into the blood? [1]
  10. June 2024, Biology Paper 7 Higher, Q14(b)(ii) (2 marks): Describe two effects of adrenaline on the human body. 1 2 [2]
  11. June 2024, Biology Paper 7 Higher, Q14(c) (3 marks): Hormones are used in the contraceptive pill. Explain how the progesterone contraceptive pill prevents pregnancy. [3]
  12. June 2023, Biology Paper 1 Foundation, Q8 (1 mark): What is the function of FSH in the female body? A It causes the eggs to mature. B It inhibits the release of progesterone. C It maintains the uterus lining. D I
  13. June 2023, Biology Paper 1 Foundation, Q10 (1 mark): Which method of contraception is the most effective? Females who became pregnant Method of while using the method of contraception contraception (%) A 1 B 8 C 9
  14. June 2023, Biology Paper 1 Foundation, Q12(b) (2 marks): The body is also controlled by the endocrine system. Complete the table to show two differences between the nervous system and the endocrine system. Nervous sys
  15. June 2023, Biology Paper 1 Foundation, Q12(c) (2 marks): Oestrogen and testosterone are both hormones. Write down one role of oestrogen and one role of testosterone in the body. Oestrogen Testosterone [2]
  16. June 2023, Biology Paper 7 Higher, Q2 (1 mark): Which method of contraception is the most effective? Females who became pregnant Method of while using the method of contraception contraception (%) A 1 B 8 C 9
  17. June 2023, Biology Paper 7 Higher, Q10 (1 mark): Which two hormones can be used in contraceptive pills to prevent ovulation during the menstrual cycle? A LH and FSH B LH and progesterone C Oestrogen and FSH D
  18. June 2023, Biology Paper 7 Higher, Q13(b) (3 marks): The body is also controlled by the endocrine system. Adrenaline and thyroxine are both hormones. Compare the roles of adrenaline and thyroxine in the body. [3]
  19. June 2022, Biology Paper 1 Foundation, Q5 (1 mark): The diagram shows the changes in female hormones during the menstrual cycle. Ovulation occurs B D C Hormone concentration in the blood A 1 2 3 4 5 6 7 8 9 10 11
  20. June 2022, Biology Paper 1 Foundation, Q11(d) (2 marks): Adrenaline is a hormone that speeds up reaction times. Describe the typical features of hormonal coordination such as adrenaline in the body. [2]
  21. June 2022, Biology Paper 7 Higher, Q6 (1 mark): Which combination of hormones is often found in contraceptive pills? A FSH and oestrogen B FSH and progesterone C Oestrogen and progesterone D Oestrogen, proges
  22. June 2022, Biology Paper 7 Higher, Q7 (1 mark): Which row shows the effects of adrenaline in the body? Breathing rate ATP production Blood flow to digestive system A increase increase increase B decrease decr
  23. June 2022, Biology Paper 7 Higher, Q8 (1 mark): The hormones controlling the menstrual cycle in cows are the same as in humans. The length of the menstrual cycle is different. The diagram shows the menstrual
  24. November 2021, Biology Paper 1 Foundation, Q5 (1 mark): Which hormone is involved in sperm production? A Insulin B Oestrogen C Progesterone D Testosterone Your answer [1]
  25. November 2021, Biology Paper 1 Foundation, Q6 (1 mark): The table shows information about five different contraceptive methods. Number of unexpected Method How it works pregnancies per 1000 women using the method rel
  26. November 2021, Biology Paper 7 Higher, Q10 (1 mark): A patient has the following symptoms: • tiredness • lack of energy • weight gain • sensitive to cold • pain in their muscle. Their doctor suggests the symptoms
  27. November 2021, Biology Paper 7 Higher, Q16(a) (2 marks): The graph shows the success rate per cycle of IVF compared to the age of the woman. 30 25 20 Success rate per cycle 15 of IVF (%) 10 5 0 20 22 24 26 28 30 32 34
  28. November 2021, Biology Paper 7 Higher, Q16(b)(i) (2 marks): Explain why these two hormones are used to treat infertility. [2]
  29. November 2021, Biology Paper 7 Higher, Q16(b)(ii) (1 mark): Use of these hormones can result in more than one embryo developing inside the uterus. This may have personal, social or economic implications for the mother. O
  30. November 2020, Biology Paper 7 Higher, Q10 (1 mark): Look at the table. Blood flow to Respiration rate Heart rate digestive system A decrease decrease decrease B decrease increase increase C increase decrease incr
  31. November 2020, Biology Paper 7 Higher, Q12(a) (2 marks): Hormones are used for coordination within the human body. Complete these sentences about hormones. Hormones are chemical . Hormones are made in glands. [2]
  32. November 2020, Biology Paper 7 Higher, Q12(b)(i) (2 marks): The diagram shows how the levels of the hormones oestrogen and progesterone change during the menstrual cycle. © A S Vink, S Clur, A A M Wilde, N A Blom, 'Effec
  33. November 2020, Biology Paper 7 Higher, Q12(b)(ii) (1 mark): What is the role of FSH in the menstrual cycle? [1]
  34. June 2019, Biology Paper 1 Foundation, Q14(a)(i) (1 mark): Which line represents the hormone progesterone? Choose from A, B, C or D [1]
  35. June 2019, Biology Paper 1 Foundation, Q14(a)(ii) (1 mark): Explain your answer to part (a)(i). [1]
  36. June 2019, Biology Paper 1 Foundation, Q14(a)(iii) (1 mark): Describe the role of progesterone in the menstrual cycle. [1]
  37. June 2019, Biology Paper 1 Foundation, Q14(b) (2 marks): Progesterone and a second hormone are used in the combined pill taken to prevent pregnancy. Explain how the combined pill works. [2]
  38. June 2019, Biology Paper 7 Higher, Q13(a)(i) (4 marks): Draw lines to the correct name for hormones A, B, C and D labelled in the diagram. A Oestrogen B FSH C LH D Progesterone [4]
  39. June 2019, Biology Paper 7 Higher, Q13(a)(ii) (2 marks): Explain how the hormones FSH and LH work to help control the menstrual cycle. [2]
  40. June 2019, Biology Paper 7 Higher, Q13(b) (2 marks): Hormones can be used in the contraceptive pill to prevent pregnancy. Explain how hormones in the contraceptive pill prevent pregnancy. [2]
  41. June 2019, Biology Paper 7 Higher, Q16(a) (2 marks): The hormone thyroxine helps to control the amount of energy available to cells. Look at the diagram. It shows how energy levels in the body are controlled. hypo
  42. June 2018, Biology Paper 1 Foundation, Q8 (1 mark): The level of some hormones change during the menstrual cycle. The graph shows how the level of one hormone changes during the menstrual cycle. Fertilisation has
  43. June 2018, Biology Paper 2 Foundation, Q13(a) (3 marks): Complete these sentences about the hormone FSH. FSH is secreted by the gland. FSH causes an to mature in the ovary. FSH stimulates the ovaries to release the ho
  44. June 2018, Biology Paper 7 Higher, Q9 (1 mark): Which of these is not an effect of adrenaline on the body? A Air passages of the lungs expand B Blood flow to the digestive system increases C Blood pressure in
  45. June 2018, Biology Paper 7 Higher, Q16(a)(i) (1 mark): Two hormones released by the pituitary are involved in controlling the menstrual cycle. Write down the names of these two hormones. and [1]
  46. June 2018, Biology Paper 7 Higher, Q16(a)(ii) (2 marks): The graph shows the levels of these two hormones during the menstrual cycle. Hormone X Hormone level Hormone Y in the blood 0 days 14 days 28 days Use the graph

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