The developing individual: meiosis, growth and development: OCR A‑Level Biology B questions
Every OCR A-Level Biology B exam question on 3.1.2 The developing individual: meiosis, growth and development, 2016–2025, with its mark scheme and examiner’s report.
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Calculations

Q5(a)
The whole paper ↗![June 2025 Paper 3, question 5(a): Describe the conclusions that can be made from the p values in the table. [2]](https://pub-e8a9dbab8e2a4d089f52b2a45e0d0b50.r2.dev/bank/h42203-jun25-05-a-qp.webp?v=3)
Q5(b)
The whole paper ↗![June 2025 Paper 3, question 5(b): Suggest what additional information is needed to increase confidence in the conclusions. [2]](https://pub-e8a9dbab8e2a4d089f52b2a45e0d0b50.r2.dev/bank/h42203-jun25-05-b-qp.webp?v=3)


![June 2025 AS Paper 2, question 6(a)(ii): Using the image, state how meiosis in plants differs from meiosis in animals. [1]](https://pub-e8a9dbab8e2a4d089f52b2a45e0d0b50.r2.dev/bank/h02202-jun25-06-aii-qp.webp?v=3)

Q2(d)
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Q2(e)
The whole paper ↗


Q33(b)(iii)
The whole paper ↗![June 2023 Paper 1, question 33(b)(iii): Explain how the production of the male and female gametes in Fig. 33.2 ensures they are genetically different to the parent plants. [3]](https://pub-e8a9dbab8e2a4d089f52b2a45e0d0b50.r2.dev/bank/h42201-jun23-33-biii-qp.webp?v=3)
Q35(a)
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Q35(b)
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![June 2022 Paper 1, question 25: What stage of meiosis is shown in the diagram? A Anaphase I B Anaphase II C Metaphase I D Prophase II Your answer [1]](https://pub-e8a9dbab8e2a4d089f52b2a45e0d0b50.r2.dev/bank/h42201-jun22-25-qp.webp?v=3)

Q5(a)(i)
The whole paper ↗![June 2022 Paper 2, question 5(a)(i): Give the name of one fetal sampling technique and state the exact source of cells used. Name of technique Source of cells [2]](https://pub-e8a9dbab8e2a4d089f52b2a45e0d0b50.r2.dev/bank/h42202-jun22-05-ai-qp.webp?v=3)
Q5(a)(ii)
The whole paper ↗![June 2022 Paper 2, question 5(a)(ii): Give the name of the technique used in the chromosome analysis of the fetal cells. [1]](https://pub-e8a9dbab8e2a4d089f52b2a45e0d0b50.r2.dev/bank/h42202-jun22-05-aii-qp.webp?v=3)
Q5(a)(iii)
The whole paper ↗![June 2022 Paper 2, question 5(a)(iii): Down’s syndrome is described as trisomy 21. Suggest what is meant by trisomy 21. [1]](https://pub-e8a9dbab8e2a4d089f52b2a45e0d0b50.r2.dev/bank/h42202-jun22-05-aiii-qp.webp?v=3)
Q5(b)(i)
The whole paper ↗![June 2022 Paper 2, question 5(b)(i): Suggest why biparietal diameter (the width of the fetus’s head at its widest point) has been replaced by head circumference as a measure of gestational age. [1]](https://pub-e8a9dbab8e2a4d089f52b2a45e0d0b50.r2.dev/bank/h42202-jun22-05-bi-qp.webp?v=3)
All 82 questions on The developing individual: meiosis, growth and development, as a list
- June 2025, Paper 1, Q10 (1 mark): The diagram shows four consecutive phases of meiosis in an animal cell. Phase 1 Phase 2 Phase 3 Phase 4 Which of the following statements is/are correct? 1 The
- June 2025, Paper 3, Q5(a) (2 marks): Describe the conclusions that can be made from the p values in the table. [2]
- June 2025, Paper 3, Q5(b) (2 marks): Suggest what additional information is needed to increase confidence in the conclusions. [2]
- June 2025, AS Paper 1, Q8 (1 mark): Which of the statements about stages in the production of the karyogram is correct? A Fetal cells were extracted using amniocentesis and then stimulated to divi
- June 2025, AS Paper 1, Q9 (1 mark): What is the correct analysis of the karyogram? A The fetus is a female with Down’s syndrome. B The fetus is a female with Klinefelter’s syndrome. C The fetus is
- June 2025, AS Paper 2, Q6(a)(ii) (1 mark): Using the image, state how meiosis in plants differs from meiosis in animals. [1]
- June 2025, AS Paper 2, Q6(b) (4 marks): The image below shows some stages of meiosis in an animal. A B C D E F Write the letters in the boxes to show the stage being described in each of the following
- June 2024, Paper 2, Q2(d) (6 marks): The diagrams show three stages of meiosis in a model cell with two pairs of chromosomes. Identify the stage of meiosis shown in each diagram. For each diagram,
- June 2024, Paper 2, Q2(e) (6 marks): Regulation of the menstrual cycle involves interaction between several hormones. (e)* Explain the importance of meiosis and fertilisation in increasing genetic
- June 2024, AS Paper 1, Q13 (1 mark): Which statement about amniocentesis and chorionic villus sampling (CVS) is correct? A Amniocentesis can be carried out much earlier in pregnancy than CVS. B Bot
- June 2023, Paper 1, Q15 (1 mark): Smoking during pregnancy can affect the growing fetus. What is the most likely effect of tobacco smoke on a growing fetus? A Inability to synthesise enzymes. B
- June 2023, Paper 1, Q33(b)(iii) (3 marks): Explain how the production of the male and female gametes in Fig. 33.2 ensures they are genetically different to the parent plants. [3]
- June 2023, Paper 1, Q35(a) (3 marks): The table shows the roles of some of the nutrients required by pregnant women as part of a balanced diet. Complete the table by stating the name of a nutrient t
- June 2023, Paper 1, Q35(b) (2 marks): In addition to dietary advice, pregnant women are offered tests to monitor their health and the health of the fetus. The tests offered includes testing urine fo
- June 2022, Paper 1, Q25 (1 mark): What stage of meiosis is shown in the diagram? A Anaphase I B Anaphase II C Metaphase I D Prophase II Your answer [1]
- June 2022, Paper 1, Q26 (1 mark): The number of possible combinations of chromosomes in a gamete of this species can be calculated using 2n where n is the haploid number of chromosomes. What is
- June 2022, Paper 2, Q5(a)(i) (2 marks): Give the name of one fetal sampling technique and state the exact source of cells used. Name of technique Source of cells [2]
- June 2022, Paper 2, Q5(a)(ii) (1 mark): Give the name of the technique used in the chromosome analysis of the fetal cells. [1]
- June 2022, Paper 2, Q5(a)(iii) (1 mark): Down’s syndrome is described as trisomy 21. Suggest what is meant by trisomy 21. [1]
- June 2022, Paper 2, Q5(b)(i) (1 mark): Suggest why biparietal diameter (the width of the fetus’s head at its widest point) has been replaced by head circumference as a measure of gestational age. [1]
- June 2022, Paper 2, Q5(b)(ii) (2 marks): Current practice states that ultrasound screening for Down’s syndrome risk should be used up to a gestational age of 14 weeks 1 day. From a gestational age of 1
- June 2022, Paper 2, Q5(b)(iii) (1 mark): Using your answer to part (ii), state whether the screening for Down’s syndrome risk of this fetus should be done by ultrasound or through a maternal blood samp
- June 2022, Paper 2, Q5(c) (2 marks): Fetal growth restriction (FGR) is a complication of pregnancy that results in a low birth weight. It affects up to 10% of all pregnancies and can lead to still-
- June 2022, AS Paper 1, Q8 (1 mark): Which of the options would result in reduced oxygen supply and poorly developed lungs in a developing fetus? A High intake of alcohol during pregnancy B High in
- June 2022, AS Paper 1, Q24(a) (4 marks): For each of these care programmes, state one test offered to women and give a reason why the test is offered. Pre-conceptual test Reason Post-conceptual test Re
- June 2022, AS Paper 1, Q24(b)(i) (2 marks): Calculate how many additional grams of protein she was advised to eat. Give your answer to 2 significant figures. Additional protein = g [2]
- June 2022, AS Paper 1, Q24(b)(ii) (1 mark): Apart from protein, name one other nutrient that the pregnant woman would be advised to increase in her daily intake. [1]
- June 2022, AS Paper 1, Q24(c)(i) (3 marks): Use the information in Fig. 24 to comment on the development of fetus G. [3]
- June 2022, AS Paper 1, Q24(c)(ii) (1 mark): Calculate the weight to length ratio for fetus H at 40 weeks gestation. Ratio = [1]
- June 2022, AS Paper 1, Q24(d) (1 mark): Biparietal diameter (BPD) measurements are also used to monitor fetal development. Describe what is meant by a BPD measurement. [1]
- November 2021, Paper 1, Q7 (1 mark): A pregnant woman has been advised to increase her daily intake of protein by 15% to 53 g. Which of the options, A to D, is her normal daily intake of protein? A
- November 2021, AS Paper 1, Q6 (1 mark): Which of the features, A to D, about the developing fetus can not be provided by an ultrasound scan? A number of chromosomes in fetal cells B position of the pl
- November 2021, AS Paper 1, Q21(a)(i) (1 mark): Which of the revision notes describes an event that occurs in meiosis II? [1]
- November 2021, AS Paper 1, Q21(a)(ii) (1 mark): Which stage of meiosis is being described in revision note 6? [1]
- November 2021, AS Paper 1, Q21(a)(iii) (1 mark): One of the revision notes is not correct. Identify this revision note and write a correction. Revision note Correction [1]
- November 2021, AS Paper 1, Q21(b) (2 marks): Crossing over is a process that occurs during meiosis. Explain how this process can lead to genetic variation in daughter cells. [2]
- November 2021, AS Paper 1, Q21(c)(i) (3 marks): Using the karyotype shown, what conclusions can be made about the fetus? Give reasons for your answer. [3]
- November 2021, AS Paper 1, Q21(c)(ii) (1 mark): Using your knowledge of meiosis, suggest how the chromosome abnormality shown in the karyotype could have occurred. [1]
- November 2021, AS Paper 1, Q21(c)(iii) (2 marks): This chromosomal abnormality usually results in miscarriage or death of the fetus. • Fetuses have this abnormality in 2% of all pregnancies. • 99% of fetuses wi
- November 2020, Paper 1, Q36(b)(i) (2 marks): Calculate the percentage of cells undergoing reduction division in the cell population. percentage of cells = % [2]
- November 2020, Paper 1, Q36(b)(ii) (2 marks): Explain how specific events in meiosis give rise to genetic variation. State the phase of meiosis in which each event takes place. [2]
- November 2020, AS Paper 1, Q8 (1 mark): In which of the stages of meiosis, A to D, are homologous chromosomes pulled to opposite poles of the cell? A metaphase I B anaphase I C metaphase II D anaphase
- November 2020, AS Paper 1, Q24(a) (3 marks): Karyotyping involves many stages. Complete the table giving reasons for each of the stages used in producing the karyotype image. Stage Reason ultrasound scan a
- November 2020, AS Paper 1, Q24(b) (2 marks): Describe the final stages of this technique which are needed to produce a karyogram from the image. [2]
- November 2020, AS Paper 1, Q24(c)(i) (2 marks): Suggest why karyotyping may have been advised in this case. [2]
- November 2020, AS Paper 1, Q24(c)(ii) (2 marks): Explain why amniocentesis was the preferred method of extracting fetal cells. [2]
- June 2019, Paper 1, Q17 (1 mark): The diagram below is a karyotype prepared from a human cell. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 X Y Which of the following statements is/a
- June 2019, Paper 1, Q25 (1 mark): Head circumference (HC) is a key indicator of fetal size and is estimated from two ultrasound measurements: • biparietal diameter (BPD) • occipitofrontal diamet
- June 2019, Paper 2, Q6(a)(i) (1 mark): Explain why meiosis is referred to as a reduction division. [1]
- June 2019, Paper 2, Q6(a)(iv) (1 mark): Some cancers that develop later in life are caused by chromosome mutation. Suggest why these cancers are unlikely to be the result of errors in meiosis. [1]
- June 2019, Paper 2, Q6(b) (6 marks): (b)* Events before conception and during pregnancy can have a significant effect on the health of a baby. Recently, scientists found there is only a small corre
- June 2019, AS Paper 1, Q14 (1 mark): During a routine visit to the antenatal clinic, a woman in the early stages of pregnancy was offered advice about why she should increase her intake of certain
- June 2019, AS Paper 2, Q4(a) (6 marks): (a)* A 25 year old pregnant woman visits her GP enquiring about antenatal care. She informs her GP that she has already stopped drinking alcohol. Explain any fu
- June 2019, AS Paper 2, Q4(c)(i) (1 mark): major defects in body structure [1]
- June 2019, AS Paper 2, Q4(c)(ii) (1 mark): major functional defects. [1]
- June 2018, Paper 1, Q6 (1 mark): Meiosis II pauses in the secondary oocyte and is only completed if fertilisation occurs. Which of the options, A to D, is a description of the last meiotic stag
- June 2018, Paper 1, Q14 (1 mark): Which of the options, A to D, is a molecule that requires vitamin C for its synthesis? A collagen B deoxyribonucleic acid C haemoglobin D rhodopsin Your answer
- June 2018, Paper 1, Q31(c)(i) (1 mark): Chorionic villus sampling (CVS) and amniocentesis are two methods of obtaining fetal cells. State the source of fetal cells that are obtained through these meth
- June 2018, Paper 1, Q31(c)(ii) (1 mark): The sample of fetal cells can be used to produce a karyotype for genetic analysis. Explain why karyotyping can not be used to detect cystic fibrosis. [1]
- June 2018, AS Paper 1, Q5 (1 mark): The number of chromosomes in a developing fetus can be checked by producing a karyogram. Which of the options, A to D, about the production of a karyogram is no
- June 2018, AS Paper 1, Q9 (1 mark): Plant life cycles show alternation of generations. The term alternation of generations is used to describe a process whereby mitosis and meiosis occur and the p
- June 2018, AS Paper 1, Q18 (1 mark): During her first antenatal appointment, a woman was advised that she needed to increase her current Dietary Reference Value (DRV) energy intake from 7800 KJ to
- June 2018, AS Paper 2, Q1(a)(ii) (1 mark): Using Fig. 1 state the number of chromosomes that would be found in the following cells taken from A. aegypti. A stem cell A sperm cell (gamete) [1]
- June 2018, AS Paper 2, Q1(b) (1 mark): After fertilisation, female mosquitoes lay their eggs directly into the external environment. Suggest one disadvantage to the embryo of developing inside eggs l
- June 2017, Paper 1, Q2 (1 mark): A karyotype of a person with a genetic disorder is shown below. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 X Y Which of the options, A to D, corre
- June 2017, Paper 2, Q2(a)(ii) (4 marks): Complete the table below to indicate the stage and type of nuclear division in which the events being described occur. Type of nuclear Stage in nuclear Event di
- June 2017, Paper 3, Q1(a) (2 marks): Calculate the rate of growth at 30 weeks’ gestation for the data shown in the uppermost curve (95th percentile). Show your working. Answer = [2]
- June 2017, Paper 3, Q1(b) (1 mark): Three sets of data are shown in Fig. 1. How can the three sets of data be used together to monitor the health of a growing fetus? [1]
- June 2017, Paper 3, Q1(c) (2 marks): The measurements for BPD in Fig. 1 were taken using ultrasound. Evaluate the usefulness of ultrasound in measuring fetal growth. [2]
- June 2017, AS Paper 1, Q17 (1 mark): Chromosome mutations can cause syndromes such as Down’s syndrome. Which of the options, A to D, is the correct chromosome content in the cells of a male with Do
- June 2017, AS Paper 1, Q23(a)(i) (3 marks): Describe how the diagnostic technique, used to produce the photograph in Fig. 23.1, is used to measure the biparietal diameter of a fetus. [3]
- June 2017, AS Paper 1, Q23(a)(ii) (2 marks): Calculate the crown-rump length (CRL) of fetus B in Fig. 23.1. Use the white line as an indicator for the positions of the crown and rump of the fetus. Show you
- June 2017, AS Paper 1, Q23(a)(iii) (1 mark): Fig. 23.2 shows a fetal growth chart. 95% 110 100 5% 90 80 70 60 crown-rump 50 length (mm) 40 30 20 10 0 6 7 8 9 10 11 12 13 14 15 gestational age (weeks) Fig.
- June 2017, AS Paper 1, Q23(a)(iv) (2 marks): Suggest two factors that must be taken into account when using the growth chart in Fig. 23.2 to estimate the gestational age of fetus B. [2]
- June 2017, AS Paper 1, Q23(b) (5 marks): Non-identical twins show as much genetic variation as other offspring. Using the most appropriate word(s), complete the sentences below about the processes that
- June 2016, AS Paper 1, Q7 (1 mark): The diagram shows four different stages in meiosis. 1 2 4 3 Which of the options, A to D, shows the correct sequence in which these four stages would occur? A 3
- June 2016, AS Paper 1, Q12 (1 mark): The chart shows biparietal diameter measurements for a fetus during its development. 8 6 biparietal 4 diameter (cm) 2 0 10 20 30 40 gestation period (weeks) Whi
- June 2016, AS Paper 1, Q20 (1 mark): Klinefelter’s syndrome can be diagnosed by looking at the arrangement of chromosomes in a karyotype. Which of the options, A to D, shows the sex chromosomes pre
- June 2016, AS Paper 1, Q24(b)(ii) (1 mark): How does the appearance of the abnormal chromosomes indicated in Fig. 24.1 differ from those in a normal cell at the same stage in the cell cycle? [1]
- June 2016, AS Paper 1, Q24(b)(iii) (3 marks): Describe the technique used to produce images of chromosomes, such as those shown in Fig. 24.1. [3]
- June 2016, AS Paper 2, Q6(a) (4 marks): A scientist wanted to observe the different stages of nuclear division. Table 6 describes some events that occur during mitosis and meiosis in plant cell sample
- June 2016, AS Paper 2, Q6(b) (2 marks): Explain how meiosis is significant in the life cycle of a plant. [2]
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