Cloning: Edexcel International GCSE Biology questions

Every Edexcel International GCSE Biology exam question on Cloning (specification points 5.17–5.20), 2019–2025, with its mark scheme and examiner’s report.

All 36 questions on Cloning, as a list

June 2025, Paper 2, Q4(a) (5 marks): Complete the passage about cloning by writing a suitable word or words in each blank space. (5) A nucleus was taken from a skin cell from Stella Cometa. This nu
June 2025, Paper 2, Q4(b) (5 marks): Until recently, most cloning has been attempted with farm animals. The table shows some information about the success rates of cloning different farm animals du
June 2025 (R), Paper 2, Q5(a) (2 marks): Calculate the percentage of embryos transferred that result in live calves being born. (2) percentage = %
June 2025 (R), Paper 2, Q5(b) (4 marks): Describe the stages in the production of a cloned mammal from an adult mammal. (4)
June 2025 (R), Paper 2, Q5(d) (4 marks): Scientists also collected data comparing cloned cattle and a control group. Table 2 shows their results. Group clones controls number of cows 10 11 mean birth m
November 2024, Paper 2, Q5 (7 marks): The passage gives information about cloning. Complete the passage by writing a suitable word in each blank space. (7) Animals such as sheep have been cloned. Cl
June 2024, Paper 2, Q1(d)(ii) (4 marks): Read the passage below. Use the information in the passage and your own knowledge to answer the questions that follow. Extinctions During the evolution of livin
June 2023, Paper 2, Q6(a)(ii) (3 marks): Micropropagation is often used to make copies of a snapdragon plant. Describe the process of micropropagation. (3)
June 2023, Paper 2, Q6(b)(i) (1 mark): Give the reason why micropropagation is used to produce the plants to be tested. (1)
June 2023 (R), Paper 2, Q1(a) (1 mark): Read the passage below. Use the information in the passage and your own knowledge to answer the questions that follow. Tissue culture and plants In micropropaga
June 2023 (R), Paper 2, Q1(b) (2 marks): Read the passage below. Use the information in the passage and your own knowledge to answer the questions that follow. Tissue culture and plants In micropropaga
June 2023 (R), Paper 2, Q1(c) (4 marks): Read the passage below. Use the information in the passage and your own knowledge to answer the questions that follow. Tissue culture and plants In micropropaga
June 2023 (R), Paper 2, Q1(f) (2 marks): Read the passage below. Use the information in the passage and your own knowledge to answer the questions that follow. Tissue culture and plants In micropropaga
June 2023 (R), Paper 2, Q1(g) (3 marks): Read the passage below. Use the information in the passage and your own knowledge to answer the questions that follow. Tissue culture and plants In micropropaga
January 2023, Paper 2, Q4(a) (2 marks): Explain why micropropagation was used to produce copies of the transgenic soya plant. (2)
January 2023 (R), Paper 2, Q7 (6 marks): The following passage contains information about using micropropagation to produce plants. Complete the passage by writing a suitable word in each blank space.
June 2022, Paper 2, Q1(e) (3 marks): Read the passage below. Use the information in the passage and your own knowledge to answer the questions that follow. Supercharging plants to reduce global war
June 2022 (R), Paper 2, Q6(a) (4 marks): Describe the stages scientists could use to clone a male horse. (4)
June 2022 (R), Paper 2, Q6(c) (1 mark): Suggest why horseracing does not allow the use of non-natural methods of breeding, including cloning. (1)
June 2022 (R), Paper 2, Q6(d) (1 mark): State one difference between cloning an organism and genetically modifying an organism. (1)
November 2021, Paper 2, Q4(a)(i) (1 mark): State the meaning of the term enucleated. (1)
November 2021, Paper 2, Q4(a)(ii) (2 marks): Describe how the single cell develops into an embryo. (2)
November 2021, Paper 2, Q4(b) (4 marks): Scientists can use adult body cells or fetal body cells to clone monkeys. The table gives information about cloning using body cells from different sources. Sou
January 2021, Paper 2, Q3(a) (1 mark): State what is meant by the term in vitro. (1)
January 2021, Paper 2, Q3(b)(i) (2 marks): Explain the relationship between pH and the mean number of shoots per explant. (2)
January 2021, Paper 2, Q3(b)(ii) (6 marks): Describe a procedure the student could use to obtain explants and produce these results. (6)
January 2021, Paper 2, Q3(c) (2 marks): Give two benefits of using micropropagation to produce new plants rather than using seeds. (2) 1 2
January 2021 (R), Paper 2, Q5(a) (1 mark): It took 277 attempts at cloning to produce one sheep. Calculate how many attempts would have been needed to produce 50 cloned sheep in 1996. Assume the same num
January 2021 (R), Paper 2, Q5(b) (5 marks): Describe the stages used to clone a male dog. (5)
January 2021 (R), Paper 2, Q5(c) (4 marks): Pet owners can now pay scientists to use cells from their pet to produce a clone. The process costs $50 000 for a dog and $25 000 for a cat. Cloning is not alwa
November 2020, Paper 2, Q2(b)(ii) (6 marks): Describe how a mammal is cloned. (6)
November 2020 (R), Paper 2, Q1(g)(i) (4 marks): Read the passage below. Use the information in the passage and your own knowledge to answer the questions that follow. Toystory Toystory is a bull who was born
November 2020 (R), Paper 2, Q1(g)(ii) (2 marks): Read the passage below. Use the information in the passage and your own knowledge to answer the questions that follow. Toystory Toystory is a bull who was born
January 2020 (R), Paper 2, Q3(b) (2 marks): Cloning was considered as a method to increase the northern white rhino population. In 2018, the only northern white rhino left was an old female. Old females p
June 2019, Paper 2, Q7(a)(i) (1 mark): Give a method that could be used to sterilise the explants in stage 2. (1)
June 2019, Paper 2, Q7(a)(ii) (1 mark): Give the name of one of the nutrients that should be added to the agar plate in stage 3. (1)

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