plumiSwitching genes on and off: Edexcel International A Level Biology questions
Every Edexcel International A Level Biology exam question on Switching genes on and off (specification points 7.22), 2019–2025, with its mark scheme and examiner’s report.
Paper
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Calculations
Q7(a)(ii)
The whole paper ↗Q2(b)(ii)
The whole paper ↗Q8(c)
The whole paper ↗Q1(b)
The whole paper ↗Q4(c)
The whole paper ↗Q8(d)
The whole paper ↗Q6(c)
The whole paper ↗Q8(g)
The whole paper ↗Q7(b)(i)
The whole paper ↗
All 9 questions on Switching genes on and off, as a list
- June 2025, Unit 5, Q7(a)(ii) (3 marks): Growth hormone is a peptide hormone that stimulates the synthesis of protein in muscle. Explain how GH stimulates the synthesis of protein in muscle. (3)
- October 2024, Unit 5, Q2(b)(ii) (3 marks): Describe how steroid hormones regulate gene transcription. (3)
- January 2024, Unit 5, Q8(c) (4 marks): Testosterone is a steroid hormone. Describe how reduced production of testosterone in the male testes can result in reduced muscle protein (paragraph 5). (4)
- October 2023, Unit 5, Q1(b) (3 marks): Describe how genes can be switched off by transcription factors. (3)
- January 2023, Unit 5, Q4(c) (4 marks): Oestrogen stimulates some types of breast cancer to proliferate. Oestrogen is a steroid hormone found in mammals. Oestrogen affects up to 100 different genes. E
- January 2022, Unit 5, Q8(d) (3 marks): Suggest how electrophilic species (ES) of free radicals could be “involved in the modulation of gene expression” (paragraph 6). (3)
- October 2021, Unit 5, Q6(c) (3 marks): Explain how cytokine genes can be expressed in an activated T lymphocyte. (3)
- June 2021, Unit 5, Q8(g) (2 marks): Suggest how myostatin might act as a negative regulator of muscle growth (paragraph 13). (2)
- January 2021, Unit 5, Q7(b)(i) (2 marks): Explain how transcription factors are involved in the synthesis of dopamine. (2)
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