plumiCystic fibrosis: Edexcel International A Level Biology questions
Edexcel International A Level Biology past-paper questions on 2.6.4 Cystic fibrosis, 2019–2025, with mark schemes and examiner’s reports where available.
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Q7(a)
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All 12 questions on Cystic fibrosis, as a list
- January 2024, AS Unit 1, Q7(a) (3 marks): Explain how this mutation results in reduced gas exchange in the lungs. (3)
- January 2024, AS Unit 1, Q7(c) (6 marks): One complication of cystic fibrosis is lung disease caused by the build-up of bacteria in the airways. This may be due to the inability of the person to clear m
- January 2023, AS Unit 1, Q3(a) (3 marks): Explain why the change in mean FEV1 was used in this investigation. (3)
- January 2023, AS Unit 1, Q3(b) (2 marks): Explain why the results of this investigation do not show that this treatment is more effective than using each drug on its own. (2)
- January 2023, AS Unit 1, Q3(c) (2 marks): Suggest why a combination of drugs could be more effective in treating people with cystic fibrosis than each drug used on its own. (2)
- January 2022, AS Unit 1, Q4(b) (3 marks): Explain how mutations result in cystic fibrosis. (3)
- June 2021, AS Unit 1, Q5(a) (3 marks): Explain why a mutation in this gene results in the production of very thick, sticky mucus. (3)
- June 2021, AS Unit 1, Q5(b) (5 marks): The diagram shows some health problems associated with cystic fibrosis, in a female. breathing difficulties problems absorbing nutrients infertility Explain why
- June 2021, AS Unit 1, Q5(c)(i) (1 mark): Which is the change in concentration of chloride ions in the sweat of an individual when the level of function of CFTR protein decreased from 100% to 18%? (1) A
- June 2021, AS Unit 1, Q5(c)(ii) (2 marks): Cystic fibrosis results from different mutations in the CFTR gene. Explain how the graph provides evidence that cystic fibrosis results from different mutations
- January 2020, AS Unit 1, Q8(a)(i) (2 marks): Calculate the percentage decrease in the diameter of the lumen of the trachea from a person with cystic fibrosis. Take your measurements between X and Y on each
- January 2020, AS Unit 1, Q8(a)(ii) (6 marks): Explain why cystic fibrosis causes the differences shown in the diagrams. (6)
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