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The nervous system and reflexes: Edexcel GCSE Combined Science questions

Every Edexcel GCSE Combined Science exam question on The nervous system and reflexes (specification points 2.13–2.14), 2018–2025, with its mark scheme and examiner’s report.

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2,937 questions

  1. Q5(a)(i)

    June 2025 · Biology Paper 1 Higher

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  2. Q5(a)(ii)

    June 2025 · Biology Paper 1 Higher

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  3. Q5(a)(iii)

    June 2025 · Biology Paper 1 Higher

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  4. Q5(a)(iv)

    June 2025 · Biology Paper 1 Higher

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  5. Q5(b)(i)

    June 2025 · Biology Paper 1 Higher

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  6. Q5(b)(ii)

    June 2025 · Biology Paper 1 Higher

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  7. Q4(a)(i)

    June 2025 · Biology Paper 1 Foundation

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    Your answer
  8. Q4(a)(ii)

    June 2025 · Biology Paper 1 Foundation

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    Your answer
  9. Q4(a)(iii)

    June 2025 · Biology Paper 1 Foundation

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  10. Q4(a)(iv)

    June 2025 · Biology Paper 1 Foundation

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  11. Q4(b)(i)

    June 2025 · Biology Paper 1 Foundation

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  12. Q4(b)(ii)

    June 2025 · Biology Paper 1 Foundation

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  13. Q4(b)(iii)

    June 2025 · Biology Paper 1 Foundation

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  14. Q6(d)(ii)

    June 2024 · Biology Paper 1 Foundation

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  15. Q6(c)

    June 2023 · Biology Paper 1 Higher

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  16. Q1(a)(i)

    November 2021 · Biology Paper 1 Higher

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  17. Q1(a)(ii)

    November 2021 · Biology Paper 1 Higher

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  18. Q1(b)(i)

    November 2021 · Biology Paper 1 Higher

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    Your answer
  19. Q1(b)(ii)

    November 2021 · Biology Paper 1 Higher

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  20. Q5(a)(i)

    November 2021 · Biology Paper 1 Foundation

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All 35 questions on The nervous system and reflexes, as a list
  1. June 2025, Biology Paper 1 Higher, Q5(a)(i) (1 mark): State how the median distance for each student could be determined from the results. (1)
  2. June 2025, Biology Paper 1 Higher, Q5(a)(ii) (2 marks): State and explain one variable that needs to be controlled in this investigation. (2)
  3. June 2025, Biology Paper 1 Higher, Q5(a)(iii) (2 marks): Figure 7 shows the results recorded for the three students. student distance in mm A 70 69 67 64 62 B 71 70 69 67 65 C 72 70 69 66 62 Figure 7 Explain one concl
  4. June 2025, Biology Paper 1 Higher, Q5(a)(iv) (3 marks): A student wanted to investigate the effect of two different drinks containing caffeine on reaction time using this method. Devise a plan the student could use.
  5. June 2025, Biology Paper 1 Higher, Q5(b)(i) (1 mark): Identify structure Z. (1)
  6. June 2025, Biology Paper 1 Higher, Q5(b)(ii) (3 marks): Figure 9 shows how the diameter of neurones affects the speed of electrical impulses. 10 8 myelinated neurones 6 speed of the electrical impulse 4 in m/s unmyel
  7. June 2025, Biology Paper 1 Foundation, Q4(a)(i) (1 mark): Which measurement should be recorded to compare reaction times? (1) A the time taken to complete the investigation B the distance the ruler falls C the distance
  8. June 2025, Biology Paper 1 Foundation, Q4(a)(ii) (1 mark): Figure 8 shows the results of five students. student distance measured in cm J 15 K 12 L 14 M 13 N 13 Figure 8 Which is the mean of the results in Figure 8? (1)
  9. June 2025, Biology Paper 1 Foundation, Q4(a)(iii) (2 marks): Explain which of the five students had the slowest reaction time. (2)
  10. June 2025, Biology Paper 1 Foundation, Q4(a)(iv) (2 marks): Give two variables that need to be controlled during this investigation. (2) 1 2
  11. June 2025, Biology Paper 1 Foundation, Q4(b)(i) (1 mark): State the role of a motor neurone in a reflex arc. (1)
  12. June 2025, Biology Paper 1 Foundation, Q4(b)(ii) (2 marks): Explain the function of the myelin sheath. (2)
  13. June 2025, Biology Paper 1 Foundation, Q4(b)(iii) (3 marks): Describe how a nerve impulse passes across the gap between two neurones. (3)
  14. June 2024, Biology Paper 1 Foundation, Q6(d)(ii) (6 marks): Beriberi can affect reflexes. Figure 10 shows a reflex arc. skin of finger neurone Y neurone X pin spinal cord muscle in arm neurone Z Figure 10 When the skin i
  15. June 2023, Biology Paper 1 Higher, Q6(c) (6 marks): The doctor also tested the reaction time of the patient. Describe the structure and function of a reflex arc. (6)
  16. November 2021, Biology Paper 1 Higher, Q1(a)(i) (3 marks): Describe how an impulse passes from the relay neurone to the motor neurone. (3)
  17. November 2021, Biology Paper 1 Higher, Q1(a)(ii) (2 marks): Explain the function of a reflex arc. (2)
  18. November 2021, Biology Paper 1 Higher, Q1(b)(i) (1 mark): Which is the median result for these students? (1) A 200 milliseconds B 210 milliseconds C 215 milliseconds D 225 milliseconds
  19. November 2021, Biology Paper 1 Higher, Q1(b)(ii) (3 marks): The scientist wanted to investigate if the colours of the squares used on the computer program affected reaction time. The computer program started with blue sq
  20. November 2021, Biology Paper 1 Foundation, Q5(a)(i) (1 mark): Draw an arrow on Figure 8 to show the direction of travel of an electrical impulse along the motor neurone. (1)
  21. November 2021, Biology Paper 1 Foundation, Q5(a)(ii) (2 marks): Name both structure K and structure L. (2) K L
  22. November 2021, Biology Paper 1 Foundation, Q5(b)(i) (3 marks): Describe how an impulse passes from the relay neurone to the motor neurone. (3)
  23. November 2021, Biology Paper 1 Foundation, Q5(b)(ii) (2 marks): Explain the function of a reflex arc. (2)
  24. November 2021, Biology Paper 1 Foundation, Q5(c)(i) (1 mark): Which is the median result for these students? (1) A 200 milliseconds B 210 milliseconds C 215 milliseconds D 225 milliseconds
  25. November 2021, Biology Paper 1 Foundation, Q5(c)(ii) (3 marks): The scientist wanted to investigate if the colours of the squares used on the computer program affected reaction time. The computer program started with blue sq
  26. November 2020, Biology Paper 1 Higher, Q5(a)(i) (2 marks): Calculate the mean difference in reaction time. Give your answer in milliseconds. (2) ms
  27. November 2020, Biology Paper 1 Higher, Q5(a)(ii) (2 marks): The drinks manufacturer wants to advertise the effect of the drink on reaction time. The manufacture needs to confirm the effect on reaction time by improving t
  28. November 2020, Biology Paper 1 Higher, Q5(b)(i) (1 mark): Name the type of neurone shown in Figure 7. (1)
  29. November 2020, Biology Paper 1 Higher, Q5(b)(ii) (1 mark): Which row identifies structure P and structure Q? (1) structure P structure Q A myelin sheath axon B cell body dendron C myelin sheath dendron D cell body axon
  30. November 2020, Biology Paper 1 Higher, Q5(c) (6 marks): Some painkillers prevent neurotransmitters binding to receptors in a synapse. Explain how a signal is transmitted at a synapse and how the painkillers reduce th
  31. June 2019, Biology Paper 1 Higher, Q6(a)(i) (2 marks): Calculate the difference between the number of neurones in the brain of the rat and the brain of the frog. Give your answer in standard form. (2) neurones
  32. June 2019, Biology Paper 1 Higher, Q6(a)(ii) (3 marks): Most neurones in the brain are unmyelinated whereas motor neurones are myelinated. Explain why myelination is needed on motor neurones but not on neurones in th
  33. June 2019, Biology Paper 1 Higher, Q6(b)(i) (1 mark): Label the axon on Figure 9. (1)
  34. June 2019, Biology Paper 1 Higher, Q6(b)(ii) (2 marks): Describe the role of sensory neurones. (2)
  35. June 2019, Biology Paper 1 Higher, Q6(c) (4 marks): Explain how impulses are transmitted at synapses. (4)

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