plumiReproduction: AQA GCSE Combined Science questions
Every AQA GCSE Combined Science exam question on 4.6.1 Reproduction, 2018–2025, with its mark scheme and examiner’s report.
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Q01.1
The whole paper ↗![June 2025 Biology Paper 2 Higher, question 01.1: Draw one line from each term to the meaning of the term relating to genetics in rabbits. [3 marks]](https://pub-e8a9dbab8e2a4d089f52b2a45e0d0b50.r2.dev/bank/8464b2h-jun25-01-1-qp.webp)
Q01.2
The whole paper ↗
Q01.3
The whole paper ↗
![June 2025 Biology Paper 2 Higher, question 01.4: How many chromosomes would be found in a skin cell of a rabbit? Use Figure 1. [1 mark] Number of chromosomes =](https://pub-e8a9dbab8e2a4d089f52b2a45e0d0b50.r2.dev/bank/8464b2h-jun25-01-4-qp.webp)
Q01.5
The whole paper ↗![June 2025 Biology Paper 2 Higher, question 01.5: The sex of a rabbit is controlled in the same way as the sex of a human. Give the evidence from Figure 1 that the rabbit is female. [1 mark]](https://pub-e8a9dbab8e2a4d089f52b2a45e0d0b50.r2.dev/bank/8464b2h-jun25-01-5-qp.webp)
Q05.1
The whole paper ↗![June 2025 Biology Paper 2 Foundation, question 05.1: Draw one line from each term to the meaning of the term relating to genetics in rabbits. [3 marks]](https://pub-e8a9dbab8e2a4d089f52b2a45e0d0b50.r2.dev/bank/8464b2f-jun25-05-1-qp.webp)
Q05.2
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Q05.3
The whole paper ↗
![June 2025 Biology Paper 2 Foundation, question 05.4: How many chromosomes would be found in a skin cell of a rabbit? Use Figure 7. [1 mark] Number of chromosomes =](https://pub-e8a9dbab8e2a4d089f52b2a45e0d0b50.r2.dev/bank/8464b2f-jun25-05-4-qp.webp)
Q05.5
The whole paper ↗![June 2025 Biology Paper 2 Foundation, question 05.5: The sex of a rabbit is controlled in the same way as the sex of a human. Give the evidence from Figure 7 that the rabbit is female. [1 mark]](https://pub-e8a9dbab8e2a4d089f52b2a45e0d0b50.r2.dev/bank/8464b2f-jun25-05-5-qp.webp)
Q02.2
The whole paper ↗![June 2024 Biology Paper 2 Higher, question 02.2: Potato plants can reproduce by asexual reproduction. Which statement is true for asexual reproduction? [1 mark] Tick () one box. Meiosis occurs. Offspring are](https://pub-e8a9dbab8e2a4d089f52b2a45e0d0b50.r2.dev/bank/8464b2h-jun24-02-2-qp.webp)
Q02.3
The whole paper ↗![June 2024 Biology Paper 2 Higher, question 02.3: Flowers of potato plants contain gametes for sexual reproduction. How is a gamete different from other cells in a potato plant? [1 mark] Tick () one box. A gam](https://pub-e8a9dbab8e2a4d089f52b2a45e0d0b50.r2.dev/bank/8464b2h-jun24-02-3-qp.webp)
Q03.1
The whole paper ↗![June 2024 Biology Paper 2 Higher, question 03.1: Describe how Figure 3 shows that the allele for AKU is recessive. [1 mark]](https://pub-e8a9dbab8e2a4d089f52b2a45e0d0b50.r2.dev/bank/8464b2h-jun24-03-1-qp.webp)
Q03.2
The whole paper ↗![June 2024 Biology Paper 2 Higher, question 03.2: Which person is definitely heterozygous for AKU? [1 mark] Tick () one box. C D E G](https://pub-e8a9dbab8e2a4d089f52b2a45e0d0b50.r2.dev/bank/8464b2h-jun24-03-2-qp.webp)
Q03.3
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Q03.4
The whole paper ↗
Q03.6
The whole paper ↗![June 2024 Biology Paper 2 Higher, question 03.6: Embryos can be screened to detect inherited disorders. Give two arguments against embryo screening. Do not refer to religion in your answer. [2 marks] 1 2](https://pub-e8a9dbab8e2a4d089f52b2a45e0d0b50.r2.dev/bank/8464b2h-jun24-03-6-qp.webp)
Q01.1
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Q01.2
The whole paper ↗![June 2024 Biology Paper 2 Foundation, question 01.2: What name is given to the allele B? [1 mark] Tick () one box. DNA Dominant Gene](https://pub-e8a9dbab8e2a4d089f52b2a45e0d0b50.r2.dev/bank/8464b2f-jun24-01-2-qp.webp)
Q01.3
The whole paper ↗![June 2024 Biology Paper 2 Foundation, question 01.3: Which term describes the genotype Bb? [1 mark] Tick () one box. Chromosome Heterozygous Phenotype](https://pub-e8a9dbab8e2a4d089f52b2a45e0d0b50.r2.dev/bank/8464b2f-jun24-01-3-qp.webp)
All 80 questions on Reproduction, as a list
- June 2025, Biology Paper 2 Higher, Q01.1 (3 marks): Draw one line from each term to the meaning of the term relating to genetics in rabbits. [3 marks]
- June 2025, Biology Paper 2 Higher, Q01.2 (5 marks): In rabbits: • the allele for brown fur (B) is dominant • the allele for white fur (b) is recessive. A rabbit with the alleles Bb and a rabbit with the alleles b
- June 2025, Biology Paper 2 Higher, Q01.3 (2 marks): A male rabbit is heterozygous for fur colour. The rabbit’s body cells have the genotype Bb. One of the sperm cells from the rabbit has the allele b. Explain why
- June 2025, Biology Paper 2 Higher, Q01.4 (1 mark): How many chromosomes would be found in a skin cell of a rabbit? Use Figure 1. [1 mark] Number of chromosomes =
- June 2025, Biology Paper 2 Higher, Q01.5 (1 mark): The sex of a rabbit is controlled in the same way as the sex of a human. Give the evidence from Figure 1 that the rabbit is female. [1 mark]
- June 2025, Biology Paper 2 Foundation, Q05.1 (3 marks): Draw one line from each term to the meaning of the term relating to genetics in rabbits. [3 marks]
- June 2025, Biology Paper 2 Foundation, Q05.2 (5 marks): In rabbits: • the allele for brown fur (B) is dominant • the allele for white fur (b) is recessive. A rabbit with the alleles Bb and a rabbit with the alleles b
- June 2025, Biology Paper 2 Foundation, Q05.3 (2 marks): A male rabbit is heterozygous for fur colour. The rabbit’s body cells have the genotype Bb. One of the sperm cells from the rabbit has the allele b. Explain why
- June 2025, Biology Paper 2 Foundation, Q05.4 (1 mark): How many chromosomes would be found in a skin cell of a rabbit? Use Figure 7. [1 mark] Number of chromosomes =
- June 2025, Biology Paper 2 Foundation, Q05.5 (1 mark): The sex of a rabbit is controlled in the same way as the sex of a human. Give the evidence from Figure 7 that the rabbit is female. [1 mark]
- June 2024, Biology Paper 2 Higher, Q02.2 (1 mark): Potato plants can reproduce by asexual reproduction. Which statement is true for asexual reproduction? [1 mark] Tick () one box. Meiosis occurs. Offspring are
- June 2024, Biology Paper 2 Higher, Q02.3 (1 mark): Flowers of potato plants contain gametes for sexual reproduction. How is a gamete different from other cells in a potato plant? [1 mark] Tick () one box. A gam
- June 2024, Biology Paper 2 Higher, Q03.1 (1 mark): Describe how Figure 3 shows that the allele for AKU is recessive. [1 mark]
- June 2024, Biology Paper 2 Higher, Q03.2 (1 mark): Which person is definitely heterozygous for AKU? [1 mark] Tick () one box. C D E G
- June 2024, Biology Paper 2 Higher, Q03.3 (5 marks): A female who has AKU and a male who is heterozygous for AKU plan to have a child. Determine the probability that the child will have AKU. You should: • complete
- June 2024, Biology Paper 2 Higher, Q03.4 (2 marks): A mutation is a change in a gene. People who have AKU have a mutation that causes the production of a non-functioning enzyme. Enzymes are proteins. Suggest how
- June 2024, Biology Paper 2 Higher, Q03.6 (2 marks): Embryos can be screened to detect inherited disorders. Give two arguments against embryo screening. Do not refer to religion in your answer. [2 marks] 1 2
- June 2024, Biology Paper 2 Foundation, Q01.1 (1 mark): Cystic fibrosis affects the movement of substances into and out of cells. Which part of a cell controls the movement of substances into and out of the cell? [1
- June 2024, Biology Paper 2 Foundation, Q01.2 (1 mark): What name is given to the allele B? [1 mark] Tick () one box. DNA Dominant Gene
- June 2024, Biology Paper 2 Foundation, Q01.3 (1 mark): Which term describes the genotype Bb? [1 mark] Tick () one box. Chromosome Heterozygous Phenotype
- June 2024, Biology Paper 2 Foundation, Q01.4 (3 marks): Two people plan to have a child. Both people have the genotype Bb. Complete Figure 1 to show the possible genotypes of the child. [3 marks] Figure 1
- June 2024, Biology Paper 2 Foundation, Q01.5 (1 mark): What is the chance that a child of these parents will have cystic fibrosis? Use Figure 1. [1 mark] Tick () one box. 0% 25% 50% 75%
- June 2024, Biology Paper 2 Foundation, Q01.6 (1 mark): An embryo can be tested to find out its genotype. What is the name of the testing process? [1 mark] Tick () one box. Genetic engineering Screening Selective br
- June 2024, Biology Paper 2 Foundation, Q06.2 (1 mark): Potato plants can reproduce by asexual reproduction. Which statement is true for asexual reproduction? [1 mark] Tick () one box. Meiosis occurs. Offspring are
- June 2024, Biology Paper 2 Foundation, Q06.3 (1 mark): Flowers of potato plants contain gametes for sexual reproduction. How is a gamete different from other cells in a potato plant? [1 mark] Tick () one box. A gam
- June 2023, Biology Paper 2 Higher, Q01.1 (1 mark): Name the type of cell division that produces egg cells and sperm cells. [1 mark]
- June 2023, Biology Paper 2 Higher, Q01.2 (2 marks): Sexual reproduction produces offspring that are genetically different from each other. Give two reasons why sexual reproduction causes variation in the offsprin
- June 2023, Biology Paper 2 Higher, Q01.3 (1 mark): A person with the genotype DD is homozygous. What word describes the genotype Dd? [1 mark]
- June 2023, Biology Paper 2 Higher, Q01.4 (5 marks): A person with the genotype Dd and a person with the genotype dd plan to have a child. Determine the probability that the child will have polydactyly. You should
- June 2023, Biology Paper 2 Higher, Q01.5 (2 marks): Embryos can be screened for the alleles that cause inherited disorders. Give two advantages of embryo screening. [2 marks] 1 2
- June 2023, Biology Paper 2 Foundation, Q06.1 (1 mark): Name the type of cell division that produces egg cells and sperm cells. [1 mark]
- June 2023, Biology Paper 2 Foundation, Q06.2 (2 marks): Sexual reproduction produces offspring that are genetically different from each other. Give two reasons why sexual reproduction causes variation in the offsprin
- June 2023, Biology Paper 2 Foundation, Q06.3 (1 mark): A person with the genotype DD is homozygous. What word describes the genotype Dd? [1 mark]
- June 2023, Biology Paper 2 Foundation, Q06.4 (5 marks): A person with the genotype Dd and a person with the genotype dd plan to have a child. Determine the probability that the child will have polydactyly. You should
- June 2023, Biology Paper 2 Foundation, Q06.5 (2 marks): Embryos can be screened for the alleles that cause inherited disorders. Give two advantages of embryo screening. [2 marks] 1 2
- June 2022, Biology Paper 2 Higher, Q05.6 (3 marks): There are two different processes of cell division in humans. Describe three differences between cell division to form sperm cells compared with cell division t
- June 2022, Biology Paper 2 Foundation, Q01.3 (1 mark): What is the name of a piece of DNA that codes for a characteristic? [1 mark]
- June 2022, Biology Paper 2 Foundation, Q01.4 (1 mark): DNA contains a code for making substances in the cell. What type of substance is made using the DNA code? [1 mark] Tick () one box. Fat Protein Starch Sugar Cy
- June 2022, Biology Paper 2 Foundation, Q01.5 (1 mark): What is a recessive allele? [1 mark] Tick () one box. An allele that is always expressed. An allele that is expressed if only one copy is present. An allele th
- June 2022, Biology Paper 2 Foundation, Q01.6 (1 mark): What word describes the alleles of the man? [1 mark] Tick () one box. Heterozygous Homozygous Phenotype
- June 2022, Biology Paper 2 Foundation, Q01.7 (3 marks): The man and the woman want to have a child. Complete Figure 1 to show the possible genotypes of the child. Draw a ring around the genotype of a child who will h
- June 2022, Biology Paper 2 Foundation, Q01.8 (1 mark): What is the chance that a child of the man and the woman will have CF? [1 mark] Tick () one box. 25% 50% 75% 100%
- June 2022, Biology Paper 2 Foundation, Q01.9 (1 mark): The woman is pregnant. The woman can have embryo screening to find out if the child will have CF. Suggest one reason why the woman might not want to have embryo
- November 2021, Biology Paper 2 Higher, Q06.1 (1 mark): Some people are heterozygous for a genetic disorder. Define the term ‘heterozygous’. [1 mark]
- November 2021, Biology Paper 2 Higher, Q06.2 (6 marks): Figure 6 shows the inheritance of a genetic disorder in a family. Figure 6 Person 7 and person 8 plan to have another child. Determine the probability that the
- November 2021, Biology Paper 2 Higher, Q06.3 (4 marks): Polydactyly is a different inherited disorder. Two parents do not have any alleles for polydactyly in their ordinary body cells. These parents produced a child
- November 2021, Biology Paper 2 Foundation, Q01.1 (1 mark): How many chromosomes does a human sperm cell contain? [1 mark] Tick () one box. 22 23 46
- November 2021, Biology Paper 2 Foundation, Q01.2 (3 marks): Draw one line from each word to the meaning of that word. [3 marks] Word Meaning Gene Genome Nucleus A small ring of DNA in the cytoplasm All the genetic materi
- November 2021, Biology Paper 2 Foundation, Q01.4 (1 mark): A person has the genotype Tt. What word describes the person’s genotype? [1 mark] Tick () one box. Heterozygous Phenotype Recessive
- November 2021, Biology Paper 2 Foundation, Q01.5 (1 mark): Give the genotype of a person who cannot taste PTC. [1 mark]
- November 2021, Biology Paper 2 Foundation, Q01.6 (2 marks): A woman and a man plan to have a child. The woman and the man both have the genotype Tt. Complete Figure 1 to show the possible genotypes of the child. [2 marks
- November 2021, Biology Paper 2 Foundation, Q01.7 (1 mark): What is the chance of the child being able to taste PTC? Use Figure 1. [1 mark] Tick () one box. 25% 50% 75% 100%
- November 2020, Biology Paper 2 Higher, Q01.1 (1 mark): Which diagram represents a DNA molecule? [1 mark] Tick () one box.
- November 2020, Biology Paper 2 Higher, Q01.2 (1 mark): Describe the structure of a DNA molecule. [1 mark]
- November 2020, Biology Paper 2 Higher, Q01.3 (2 marks): A gene is a small section of DNA on a chromosome. Complete the sentences. [2 marks] A gene codes for a particular sequence of . This sequence makes a specific .
- November 2020, Biology Paper 2 Higher, Q01.4 (1 mark): What is meant by the term genome? [1 mark]
- November 2020, Biology Paper 2 Higher, Q01.5 (1 mark): The complete human genome is now known. Which important scientific advance was made using knowledge of the human genome? [1 mark] Tick () one box. Discovering
- November 2020, Biology Paper 2 Higher, Q04.1 (2 marks): In sexual reproduction, cells divide by meiosis to form gametes. Which two statements are true for cell division by meiosis? [2 marks] Tick () two boxes. Daugh
- November 2020, Biology Paper 2 Higher, Q04.4 (2 marks): Suggest two advantages for garden centres of growing geraniums by asexual reproduction compared with sexual reproduction. [2 marks] 1 2
- November 2020, Biology Paper 2 Higher, Q04.5 (2 marks): Suggest two disadvantages for garden centres of growing geraniums by asexual reproduction compared with sexual reproduction. [2 marks] 1 2
- November 2020, Biology Paper 2 Higher, Q05.1 (2 marks): Complete Figure 5. [2 marks] Figure 5 Female X X Male
- November 2020, Biology Paper 2 Higher, Q05.2 (1 mark): In some families all children are the same sex. Give the reason why. [1 mark]
- November 2020, Biology Paper 2 Higher, Q05.3 (4 marks): A man and a woman do not have CF. The man and the woman have a child who has CF. Draw a Punnett square diagram to find the probability that their next child wil
- November 2020, Biology Paper 2 Higher, Q05.4 (3 marks): Suggest three reasons for choosing Method 1 instead of Method 2. [3 marks] 1 2 3
- November 2020, Biology Paper 2 Higher, Q05.5 (1 mark): Suggest one advantage of Method 2. [1 mark]
- November 2020, Biology Paper 2 Foundation, Q01.1 (2 marks): Which two statements are true for sexual reproduction in humans? [2 marks] Tick () two boxes. Gametes are formed. Offspring are clones. Offspring are genetical
- November 2020, Biology Paper 2 Foundation, Q01.2 (3 marks): Humans reproduce by sexual reproduction. Complete Figure 1 to show the inheritance of sex. [3 marks] Figure 1 Mother X X Father X XX
- November 2020, Biology Paper 2 Foundation, Q01.3 (1 mark): Draw a ring around the genotype of all male children in Figure 1. [1 mark]
- November 2020, Biology Paper 2 Foundation, Q06.1 (1 mark): Which diagram represents a DNA molecule? [1 mark] Tick () one box.
- November 2020, Biology Paper 2 Foundation, Q06.2 (1 mark): Describe the structure of a DNA molecule. [1 mark]
- November 2020, Biology Paper 2 Foundation, Q06.3 (2 marks): A gene is a small section of DNA on a chromosome. Complete the sentences. [2 marks] A gene codes for a particular sequence of . This sequence makes a specific .
- November 2020, Biology Paper 2 Foundation, Q06.4 (1 mark): What is meant by the term genome? [1 mark]
- November 2020, Biology Paper 2 Foundation, Q06.5 (1 mark): The complete human genome is now known. Which important scientific advance was made using knowledge of the human genome? [1 mark] Tick () one box. Discovering
- June 2019, Biology Paper 2 Higher, Q03.4 (2 marks): Scientists working on the ‘Human Genome Project’ have now mapped the entire genetic code of humans. Explain one way this could be important for people in the fu
- June 2019, Biology Paper 2 Higher, Q04.4 (2 marks): The DNA code determines the sequence of amino acids which are joined together to form a specific protein. Table 3 shows part of the amino acid sequence for the
- June 2018, Biology Paper 2 Higher, Q07.1 (1 mark): Which arrangement of chromosomes will a male oyster have in each body cell? [1 mark] Tick one box. One X and one Y chromosome and 8 pairs of other chromosomes T
- June 2018, Biology Paper 2 Higher, Q07.2 (3 marks): Oyster gametes only contain half the amount of DNA compared to a normal oyster body cell. Describe the type of cell division that produces gametes. [3 marks]
- June 2018, Biology Paper 2 Higher, Q07.3 (1 mark): Suggest why the triploid oysters are not able to reproduce. [1 mark]
- June 2018, Biology Paper 2 Higher, Q07.4 (2 marks): Explain why the triploid oysters grow more quickly than the diploid oysters. [2 marks]
- June 2018, Biology Paper 2 Higher, Q07.6 (6 marks): Oyster farmers grow the triploid oysters from young seed oysters. The production of seed oysters involves the use of a chemical called cytochalasin B. Cytochala
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