Hormonal coordination in humans: AQA GCSE Combined Science questions

Every AQA GCSE Combined Science exam question on 4.5.3 Hormonal coordination in humans, 2018–2025, with its mark scheme and examiner’s report.

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3,069 questions

Q02.1
June 2025 · Biology Paper 2 Higher
1 mark4.5.3 Hormonal coordination in humans
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Q02.2
June 2025 · Biology Paper 2 Higher
1 mark4.5.3 Hormonal coordination in humans
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Q02.3
June 2025 · Biology Paper 2 Higher
1 mark4.5.3 Hormonal coordination in humans
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Q02.4
June 2025 · Biology Paper 2 Higher
6 marks4.5.3 Hormonal coordination in humans
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Q06.1
June 2025 · Biology Paper 2 Higher
1 mark4.5.3 Hormonal coordination in humans
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Q06.2
June 2025 · Biology Paper 2 Higher
6 marks4.5.3 Hormonal coordination in humans
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Q06.3
June 2025 · Biology Paper 2 Higher
1 mark4.5.3 Hormonal coordination in humans
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Q06.4
June 2025 · Biology Paper 2 Higher
4 marks4.5.3 Hormonal coordination in humans 4.4.2 Respiration
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Q01.1
June 2025 · Biology Paper 2 Foundation
1 mark4.5.3 Hormonal coordination in humans
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Q01.2
June 2025 · Biology Paper 2 Foundation
1 mark4.5.3 Hormonal coordination in humans
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Q01.3
June 2025 · Biology Paper 2 Foundation
2 marks4.5.3 Hormonal coordination in humans
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Q01.4
June 2025 · Biology Paper 2 Foundation
2 marks4.5.3 Hormonal coordination in humans
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Q01.5
June 2025 · Biology Paper 2 Foundation
1 mark4.5.3 Hormonal coordination in humans
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Q01.6
June 2025 · Biology Paper 2 Foundation
2 marks4.5.3 Hormonal coordination in humans
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Q06.1
June 2025 · Biology Paper 2 Foundation
1 mark4.5.3 Hormonal coordination in humans
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Q06.2
June 2025 · Biology Paper 2 Foundation
1 mark4.5.3 Hormonal coordination in humans
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Q06.3
June 2025 · Biology Paper 2 Foundation
1 mark4.5.3 Hormonal coordination in humans
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Q06.4
June 2025 · Biology Paper 2 Foundation
6 marks4.5.3 Hormonal coordination in humans
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Q03.5
June 2024 · Biology Paper 2 Higher
4 marks4.5.3 Hormonal coordination in humans
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Q04.1
June 2024 · Biology Paper 2 Higher
2 marks4.5.3 Hormonal coordination in humans
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All 98 questions on Hormonal coordination in humans, as a list

June 2025, Biology Paper 2 Higher, Q02.1 (1 mark): Name one hormone produced in the ovaries. [1 mark]
June 2025, Biology Paper 2 Higher, Q02.2 (1 mark): Give one function of the hormone that is produced in the testes. [1 mark] Different methods of contraception can involve: • barriers • hormones.
June 2025, Biology Paper 2 Higher, Q02.3 (1 mark): Condoms are a barrier method of contraception. Give one advantage of condoms as a method of contraception compared with hormonal methods of contraception. Do no
June 2025, Biology Paper 2 Higher, Q02.4 (6 marks): Describe how hormones are used in different methods of contraception. [6 marks]
June 2025, Biology Paper 2 Higher, Q06.1 (1 mark): Which equation represents a linear relationship? [1 mark] Tick () one box. y = mc + x y = mc2 + x y = mx + c y = mx2 + c
June 2025, Biology Paper 2 Higher, Q06.2 (6 marks): When the body makes insulin, C-peptide is also made. The concentration of C-peptide in the blood is not increased by insulin injections. Some people with Type 2
June 2025, Biology Paper 2 Higher, Q06.3 (1 mark): Which organ produces glucagon? [1 mark] Tick () one box. Liver Pancreas Small intestine Stomach
June 2025, Biology Paper 2 Higher, Q06.4 (4 marks): In some people, glucagon is produced in smaller quantities than is needed. Explain why people who do not produce enough glucagon feel weak and tired. [4 marks]
June 2025, Biology Paper 2 Foundation, Q01.1 (1 mark): A person drinks a glucose solution. What happens to the person’s blood glucose concentration soon after drinking the glucose solution? [1 mark] Tick () one box
June 2025, Biology Paper 2 Foundation, Q01.2 (1 mark): Insulin controls blood glucose concentration. Which organ produces insulin? [1 mark] Tick () one box. Pancreas Pituitary Stomach
June 2025, Biology Paper 2 Foundation, Q01.3 (2 marks): Organs affected by insulin are called target organs. Which two organs are target organs for insulin? [2 marks] Tick () two boxes. Liver Lung Muscle Ovary Spina
June 2025, Biology Paper 2 Foundation, Q01.4 (2 marks): Complete the sentences. Choose answers from the box. [2 marks] DNA glucose glycogen urea Insulin causes cells to take in . The storage molecule made inside the
June 2025, Biology Paper 2 Foundation, Q01.5 (1 mark): Complete the sentence. Choose the answer from the box. [1 mark] increase stay the same decrease Insulin causes blood glucose concentration to .
June 2025, Biology Paper 2 Foundation, Q01.6 (2 marks): Type 2 diabetes is caused when the body cells no longer respond to insulin. Give two ways to reduce the risk of developing Type 2 diabetes. Do not refer to insu
June 2025, Biology Paper 2 Foundation, Q06.1 (1 mark): Name one hormone produced in the ovaries. [1 mark]
June 2025, Biology Paper 2 Foundation, Q06.2 (1 mark): Give one function of the hormone that is produced in the testes. [1 mark] Different methods of contraception can involve: • barriers • hormones.
June 2025, Biology Paper 2 Foundation, Q06.3 (1 mark): Condoms are a barrier method of contraception. Give one advantage of condoms as a method of contraception compared with hormonal methods of contraception. Do no
June 2025, Biology Paper 2 Foundation, Q06.4 (6 marks): Describe how hormones are used in different methods of contraception. [6 marks]
June 2024, Biology Paper 2 Higher, Q03.5 (4 marks): Some people have In Vitro Fertilisation (IVF) treatment to increase the chance of becoming pregnant. Describe how the process of IVF can result in pregnancy. [4
June 2024, Biology Paper 2 Higher, Q04.1 (2 marks): When rats compete, the basal metabolic rate of the rats increases. Basal metabolic rate is controlled in the same way in humans and in rats. Describe how basal
June 2024, Biology Paper 2 Higher, Q06.1 (1 mark): Which gland releases hormones to control other glands? [1 mark] Tick () one box. Adrenal Pituitary Thyroid
June 2024, Biology Paper 2 Higher, Q06.2 (1 mark): Adrenaline can increase blood glucose concentration. What is one other effect of adrenaline? [1 mark] Tick () one box. Decreased breathing rate Decreased metab
June 2024, Biology Paper 2 Higher, Q06.4 (2 marks): People with Type 1 diabetes were selected for the investigation instead of people who did not have diabetes. Explain why. [2 marks]
June 2024, Biology Paper 2 Higher, Q06.5 (2 marks): Control variables between the different people in the investigation included: • age • sex • food and drink consumed before and during the test. Suggest two othe
June 2024, Biology Paper 2 Higher, Q06.6 (1 mark): It was important for the scientists to monitor the health of each person during the investigation. Suggest one reason why. [1 mark] Figure 6 shows the results.
June 2024, Biology Paper 2 Higher, Q06.7 (2 marks): People who do not have diabetes usually have a blood glucose concentration in the range of 4.0 mmol/dm3 to 7.8 mmol/dm3. Describe how the results in Figure 6 sh
June 2024, Biology Paper 2 Higher, Q06.8 (5 marks): Describe how blood glucose concentration is maintained within narrow limits in people who do not have diabetes. [5 marks]
June 2024, Biology Paper 2 Foundation, Q02.1 (3 marks): Label the glands on Figure 2. Choose answers from the box. [3 marks] adrenal gland ovary pituitary gland testis thyroid gland
June 2024, Biology Paper 2 Foundation, Q02.2 (1 mark): Cells in the pancreas detect blood glucose concentration. What type of cells detect blood glucose concentration? [1 mark] Tick () one box. Coordinator cells Mu
June 2024, Biology Paper 2 Foundation, Q02.3 (1 mark): The pancreas produces insulin. How is insulin transported from the pancreas to the rest of the body? [1 mark]
June 2024, Biology Paper 2 Foundation, Q02.4 (1 mark): Which organ is a target organ of insulin? [1 mark] Tick () one box. Liver Small intestine Stomach
June 2024, Biology Paper 2 Foundation, Q02.5 (1 mark): Which chemical is a store of glucose in human cells? [1 mark] Tick () one box. Cellulose Glycogen Protein
June 2024, Biology Paper 2 Foundation, Q02.6 (1 mark): What was the change in blood glucose concentration in person A from 0 minutes to 60 minutes? [1 mark] Change = arbitrary units
June 2024, Biology Paper 2 Foundation, Q02.7 (2 marks): Describe the trend in the relationship between blood glucose concentration and time after the meal. [2 marks]
June 2024, Biology Paper 2 Foundation, Q02.8 (2 marks): A student concluded: ‘Person A has diabetes’. Explain how Figure 3 supports the student’s conclusion. You should refer to insulin in your answer. [2 marks]
June 2024, Biology Paper 2 Foundation, Q02.9 (2 marks): Describe two ways a person with Type 2 diabetes could change their lifestyle to control their diabetes. [2 marks] 1 2
June 2023, Biology Paper 2 Higher, Q05.1 (1 mark): Which hormones are given to women having IVF treatment? [1 mark] Tick () one box. FSH and LH FSH and oestrogen LH and oestrogen
June 2023, Biology Paper 2 Higher, Q05.2 (1 mark): Name the target organ of the hormones used for IVF. [1 mark]
June 2023, Biology Paper 2 Higher, Q05.3 (1 mark): Describe why microscopes are needed in the process of IVF. [1 mark]
June 2023, Biology Paper 2 Higher, Q05.4 (3 marks): Describe how the hormones given to women during IVF treatment interact with other hormones to prepare the body for pregnancy. [3 marks]
June 2023, Biology Paper 2 Higher, Q05.5 (2 marks): Calculate the simplest ratio of the number of women who had successful IVF to the number of women who had unsuccessful IVF. Give the ratio in whole numbers. [2
June 2023, Biology Paper 2 Higher, Q05.6 (1 mark): Suggest one factor that can affect the probability of a woman having a child as a result of IVF treatment. [1 mark]
June 2023, Biology Paper 2 Higher, Q05.7 (2 marks): Give two arguments against the use of IVF treatment. Do not refer to cost or to religion in your answer. [2 marks] 1 2
June 2023, Biology Paper 2 Higher, Q06.5 (1 mark): Which gland secretes hormones to stimulate the adrenal glands? [1 mark]
June 2023, Biology Paper 2 Higher, Q06.6 (5 marks): Explain the role of the adrenal glands in responding to a decrease in body temperature. [5 marks]
June 2023, Biology Paper 2 Higher, Q06.7 (3 marks): Explain how the thyroid gland controls the response to a decrease in body temperature by negative feedback. [3 marks]
June 2023, Biology Paper 2 Foundation, Q05.6 (1 mark): Complete the sentence. Choose the answer from the box. [1 mark] heart pancreas stomach Insulin is produced by the .
June 2023, Biology Paper 2 Foundation, Q05.7 (1 mark): Insulin is a hormone. Which organ system produces hormones? [1 mark]
June 2023, Biology Paper 2 Foundation, Q05.8 (1 mark): Complete the sentence. Choose the answer from the box. [1 mark] decrease stay the same increase When insulin concentration in the blood increases, blood glucose
June 2023, Biology Paper 2 Foundation, Q05.9 (1 mark): Give one risk factor for Type 2 diabetes. [1 mark]
June 2022, Biology Paper 2 Higher, Q05.1 (1 mark): Name the type of hormonal control shown in Figure 4. [1 mark]
June 2022, Biology Paper 2 Higher, Q05.2 (1 mark): Name hormones A and B in Figure 4. [1 mark] A B
June 2022, Biology Paper 2 Higher, Q05.3 (6 marks): Explain how the two hormones in Figure 4 keep the blood glucose concentration within the normal range for 3 hours after a meal. [6 marks]
June 2022, Biology Paper 2 Higher, Q05.4 (3 marks): Follicle Stimulating Hormone (FSH) and then Luteinising Hormone (LH) can be injected into a woman to help her become pregnant by sexual intercourse. Explain how
June 2022, Biology Paper 2 Higher, Q05.5 (4 marks): In some women the injections of FSH and LH are the first steps for In Vitro Fertilisation (IVF). Describe the remaining steps in IVF. [4 marks]
June 2022, Biology Paper 2 Foundation, Q04.1 (1 mark): Which letter shows the pancreas? [1 mark] Tick () one box. A B C D
June 2022, Biology Paper 2 Foundation, Q04.2 (1 mark): Which letter shows the thyroid gland? [1 mark] Tick () one box. A B C D
June 2022, Biology Paper 2 Foundation, Q04.3 (1 mark): Hormones travel from the gland where they are made to the target organ where they have an effect. How do hormones travel from the gland to the target organ? [1
June 2022, Biology Paper 2 Foundation, Q04.4 (1 mark): Name hormone X. [1 mark]
June 2022, Biology Paper 2 Foundation, Q04.5 (2 marks): In what two ways does hormone X cause a decrease in blood glucose concentration? [2 marks] Tick () two boxes. Glucose is broken down. Glucose is converted to g
June 2022, Biology Paper 2 Foundation, Q04.6 (1 mark): Suggest what time of day the woman ate her breakfast of sugar-coated cereal. [1 mark] Time of day =
June 2022, Biology Paper 2 Foundation, Q04.7 (1 mark): The man ate: • the same type and amount of breakfast cereal as the woman • at the same time as the woman. Suggest what his blood glucose concentration would be
June 2022, Biology Paper 2 Foundation, Q04.8 (2 marks): The man: • is an obese office worker • does not exercise • eats sugary snacks at his desk. Give two lifestyle changes a doctor might recommend to the man to hel
June 2022, Biology Paper 2 Foundation, Q04.9 (2 marks): Describe how a low blood glucose concentration would lead to a person feeling weak. [2 marks]
November 2021, Biology Paper 2 Higher, Q01.1 (1 mark): Which organ system includes the glands shown in Figure 1? [1 mark]
November 2021, Biology Paper 2 Higher, Q01.2 (1 mark): Which gland produces insulin? [1 mark] Tick () one box. A B C D
November 2021, Biology Paper 2 Higher, Q01.3 (1 mark): Which gland produces hormones that stimulate the other glands to produce hormones? [1 mark] Tick () one box. A B C D
November 2021, Biology Paper 2 Higher, Q01.4 (1 mark): How do hormones travel from one gland to another gland? [1 mark]
November 2021, Biology Paper 2 Higher, Q01.5 (2 marks): Name two glands involved in human reproduction. Do not refer to glands shown on Figure 1 in your answer. [2 marks] 1 2
November 2021, Biology Paper 2 Higher, Q01.6 (1 mark): Ovulation test kits can help women know when they are most fertile. Ovulation test kits detect the increase in the hormone that stimulates ovulation. Which horm
November 2021, Biology Paper 2 Higher, Q01.7 (6 marks): A new contraceptive drug for men is being tested. The drug: • is given in one injection • stops sperm being able to fertilise eggs • is effective for up to 13 y
November 2021, Biology Paper 2 Higher, Q05.5 (4 marks): Caffeine causes the release of adrenaline. Adrenaline affects heart rate. Explain how the effect of adrenaline on heart rate might cause reaction time to decrea
November 2021, Biology Paper 2 Foundation, Q06.1 (1 mark): Which organ system includes the glands shown in Figure 5? [1 mark]
November 2021, Biology Paper 2 Foundation, Q06.2 (1 mark): Which gland produces insulin? [1 mark] Tick () one box. A B C D
November 2021, Biology Paper 2 Foundation, Q06.3 (1 mark): Which gland produces hormones that stimulate the other glands to produce hormones? [1 mark] Tick () one box. A B C D
November 2021, Biology Paper 2 Foundation, Q06.4 (1 mark): How do hormones travel from one gland to another gland? [1 mark]
November 2021, Biology Paper 2 Foundation, Q06.5 (2 marks): Name two glands involved in human reproduction. Do not refer to glands shown on Figure 5 in your answer. [2 marks] 1 2
November 2021, Biology Paper 2 Foundation, Q06.6 (1 mark): Ovulation test kits can help women know when they are most fertile. Ovulation test kits detect the increase in the hormone that stimulates ovulation. Which horm
November 2021, Biology Paper 2 Foundation, Q06.7 (6 marks): A new contraceptive drug for men is being tested. The drug: • is given in one injection • stops sperm being able to fertilise eggs • is effective for up to 13 y
November 2020, Biology Paper 2 Higher, Q04.2 (3 marks): Label the endocrine glands on Figure 3. [3 marks]
November 2020, Biology Paper 2 Higher, Q04.3 (3 marks): Complete Table 2. [3 marks] Table 2 Hormone Name of gland which releases hormone Target organ of hormone Luteinising hormone (LH) Pituitary gland Adrenal gland
November 2020, Biology Paper 2 Higher, Q05.4 (3 marks): Suggest three reasons for choosing Method 1 instead of Method 2. [3 marks] 1 2 3
November 2020, Biology Paper 2 Higher, Q05.5 (1 mark): Suggest one advantage of Method 2. [1 mark]
November 2020, Biology Paper 2 Foundation, Q01.4 (2 marks): When children reach puberty, reproductive hormones cause changes in their bodies. Draw one line from each hormone to the change the hormone causes at puberty. [
November 2020, Biology Paper 2 Foundation, Q01.5 (2 marks): Draw one line from each method of contraception to how the method prevents pregnancy. [2 marks] Method of contraception How the method prevents pregnancy Condom
November 2020, Biology Paper 2 Foundation, Q01.6 (2 marks): Give one advantage and one disadvantage of taking oral contraceptives to prevent pregnancy. [2 marks] Advantage Disadvantage
November 2020, Biology Paper 2 Foundation, Q04.2 (1 mark): What is the name of gland A? [1 mark] Tick () one box. Pancreas Pituitary Thyroid Before eating a sugar-coated cereal a person had a blood glucose concentratio
November 2020, Biology Paper 2 Foundation, Q04.3 (1 mark): Calculate the increase in the blood glucose concentration. [1 mark] Increase = mmol/dm3
November 2020, Biology Paper 2 Foundation, Q04.4 (1 mark): The person needed medication to decrease their blood glucose concentration. Suggest what disorder the person has. [1 mark]
November 2020, Biology Paper 2 Foundation, Q04.5 (1 mark): There is a problem with the hormone control of the person. What is the problem? [1 mark] Tick () one box. The blood is not taking hormones to target organs. Th
November 2020, Biology Paper 2 Foundation, Q04.6 (2 marks): The person: • works in an office • drives to work • is overweight • watches the television and reads every night • drinks a hot chocolate every night. Suggest t
June 2019, Biology Paper 2 Higher, Q06.2 (1 mark): Name the hormone released if the blood glucose concentration falls too low. [1 mark] Two people were sent to a hospital to find out if they have diabetes. This
June 2019, Biology Paper 2 Higher, Q06.3 (3 marks): Describe how Figure 4 shows that person B has diabetes. Use data from Figure 4. [3 marks]
June 2019, Biology Paper 2 Higher, Q06.4 (2 marks): Person A and person B had a test to measure the concentration of insulin in their blood when they were fasting. Table 4 shows the results. Table 4 Person Fastin
June 2019, Biology Paper 2 Higher, Q06.5 (6 marks): Toxic hypoglycaemia syndrome (THS) has caused the deaths of hundreds of starving children in some tropical countries. • The starving children have had nothing t
June 2018, Biology Paper 2 Higher, Q06.1 (2 marks): Calculate the rate of increase in LH concentration between day 9 and day 12 Give your answer in arbitrary units per hour. Give your answer to 2 significant figu
June 2018, Biology Paper 2 Higher, Q06.2 (5 marks): Describe the sequence of hormone interactions in the menstrual cycle. Name where each hormone is produced. [5 marks]
June 2018, Biology Paper 2 Higher, Q06.3 (1 mark): Progesterone is used in some contraceptives. Suggest one advantage of using a progesterone patch rather than a progesterone oral contraceptive. [1 mark]

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