Communicable diseases: AQA GCSE Combined Science questions
Every AQA GCSE Combined Science exam question on 4.3.1 Communicable diseases, 2018–2025, with its mark scheme and examiner’s report.
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Q02.1
The whole paper ↗![June 2025 Biology Paper 1 Higher, question 02.1: One symptom of chickenpox is small blisters on the skin. Suggest one way chickenpox spreads from an infected person to other people. [1 mark]](https://pub-e8a9dbab8e2a4d089f52b2a45e0d0b50.r2.dev/bank/8464b1h-jun25-02-1-qp.webp)
Q02.2
The whole paper ↗![June 2025 Biology Paper 1 Higher, question 02.2: Chickenpox is caused by a type of pathogen that cannot be treated with antibiotics. Give the reason why chickenpox cannot be treated with antibiotics. [1 mark]](https://pub-e8a9dbab8e2a4d089f52b2a45e0d0b50.r2.dev/bank/8464b1h-jun25-02-2-qp.webp)
Q02.3
The whole paper ↗![June 2025 Biology Paper 1 Higher, question 02.3: What does a vaccine contain that causes a person to become immune to a disease? [1 mark]](https://pub-e8a9dbab8e2a4d089f52b2a45e0d0b50.r2.dev/bank/8464b1h-jun25-02-3-qp.webp)
Q02.4
The whole paper ↗![June 2025 Biology Paper 1 Higher, question 02.4: Give three reasons why a new vaccine must be tested. [3 marks] 1 2 3](https://pub-e8a9dbab8e2a4d089f52b2a45e0d0b50.r2.dev/bank/8464b1h-jun25-02-4-qp.webp)
Q02.5
The whole paper ↗
Q06.2
The whole paper ↗![June 2025 Biology Paper 1 Higher, question 06.2: Describe the function of ciliated cells in the oviduct. [1 mark]](https://pub-e8a9dbab8e2a4d089f52b2a45e0d0b50.r2.dev/bank/8464b1h-jun25-06-2-qp.webp)
Q02.8
The whole paper ↗![June 2025 Biology Paper 1 Foundation, question 02.8: How could the fungal infection be removed from the tree? [1 mark] Tick () one box. Destroy the affected leaves. Spray the affected leaves with antibiotics. Use](https://pub-e8a9dbab8e2a4d089f52b2a45e0d0b50.r2.dev/bank/8464b1f-jun25-02-8-qp.webp)
Q02.9
The whole paper ↗
Q06.1
The whole paper ↗![June 2025 Biology Paper 1 Foundation, question 06.1: One symptom of chickenpox is small blisters on the skin. Suggest one way chickenpox spreads from an infected person to other people. [1 mark]](https://pub-e8a9dbab8e2a4d089f52b2a45e0d0b50.r2.dev/bank/8464b1f-jun25-06-1-qp.webp)
Q06.2
The whole paper ↗![June 2025 Biology Paper 1 Foundation, question 06.2: Chickenpox is caused by a type of pathogen that cannot be treated with antibiotics. Give the reason why chickenpox cannot be treated with antibiotics. [1 mark]](https://pub-e8a9dbab8e2a4d089f52b2a45e0d0b50.r2.dev/bank/8464b1f-jun25-06-2-qp.webp)
Q06.3
The whole paper ↗![June 2025 Biology Paper 1 Foundation, question 06.3: What does a vaccine contain that causes a person to become immune to a disease? [1 mark]](https://pub-e8a9dbab8e2a4d089f52b2a45e0d0b50.r2.dev/bank/8464b1f-jun25-06-3-qp.webp)
Q06.4
The whole paper ↗![June 2025 Biology Paper 1 Foundation, question 06.4: Give three reasons why a new vaccine must be tested. [3 marks] 1 2 3](https://pub-e8a9dbab8e2a4d089f52b2a45e0d0b50.r2.dev/bank/8464b1f-jun25-06-4-qp.webp)
Q06.5
The whole paper ↗
Q03.1
The whole paper ↗![June 2024 Biology Paper 1 Higher, question 03.1: What type of microorganism causes measles? [1 mark]](https://pub-e8a9dbab8e2a4d089f52b2a45e0d0b50.r2.dev/bank/8464b1h-jun24-03-1-qp.webp)
Q03.2
The whole paper ↗![June 2024 Biology Paper 1 Higher, question 03.2: Suggest two ways the spread of measles can be reduced. Do not refer to vaccination in your answer. [2 marks] 1 2](https://pub-e8a9dbab8e2a4d089f52b2a45e0d0b50.r2.dev/bank/8464b1h-jun24-03-2-qp.webp)
Q03.3
The whole paper ↗![June 2024 Biology Paper 1 Higher, question 03.3: Describe how the measles vaccine helps a person to become immune to the measles pathogen. [4 marks]](https://pub-e8a9dbab8e2a4d089f52b2a45e0d0b50.r2.dev/bank/8464b1h-jun24-03-3-qp.webp)
Q03.4
The whole paper ↗![June 2024 Biology Paper 1 Higher, question 03.4: Explain how viruses cause illness. [2 marks]](https://pub-e8a9dbab8e2a4d089f52b2a45e0d0b50.r2.dev/bank/8464b1h-jun24-03-4-qp.webp)
Q03.5
The whole paper ↗
Q04.1
The whole paper ↗![June 2024 Biology Paper 1 Foundation, question 04.1: Which is a symptom of gonorrhoea? [1 mark] Tick () one box. Damaged immune system Pain when urinating Reduced body temperature Table 2 shows the number of repo](https://pub-e8a9dbab8e2a4d089f52b2a45e0d0b50.r2.dev/bank/8464b1f-jun24-04-1-qp.webp)
Q04.2
The whole paper ↗![June 2024 Biology Paper 1 Foundation, question 04.2: The number of cases of gonorrhoea in each city might not be accurate. Suggest one reason why. [1 mark]](https://pub-e8a9dbab8e2a4d089f52b2a45e0d0b50.r2.dev/bank/8464b1f-jun24-04-2-qp.webp)
All 101 questions on Communicable diseases, as a list
- June 2025, Biology Paper 1 Higher, Q02.1 (1 mark): One symptom of chickenpox is small blisters on the skin. Suggest one way chickenpox spreads from an infected person to other people. [1 mark]
- June 2025, Biology Paper 1 Higher, Q02.2 (1 mark): Chickenpox is caused by a type of pathogen that cannot be treated with antibiotics. Give the reason why chickenpox cannot be treated with antibiotics. [1 mark]
- June 2025, Biology Paper 1 Higher, Q02.3 (1 mark): What does a vaccine contain that causes a person to become immune to a disease? [1 mark]
- June 2025, Biology Paper 1 Higher, Q02.4 (3 marks): Give three reasons why a new vaccine must be tested. [3 marks] 1 2 3
- June 2025, Biology Paper 1 Higher, Q02.5 (6 marks): Explain how a vaccine for chickenpox gives immunity against the disease. You should refer to how the body responds to: • the vaccine • chickenpox pathogens that
- June 2025, Biology Paper 1 Higher, Q06.2 (1 mark): Describe the function of ciliated cells in the oviduct. [1 mark]
- June 2025, Biology Paper 1 Foundation, Q02.8 (1 mark): How could the fungal infection be removed from the tree? [1 mark] Tick () one box. Destroy the affected leaves. Spray the affected leaves with antibiotics. Use
- June 2025, Biology Paper 1 Foundation, Q02.9 (3 marks): Infection with apple scab fungus decreases the number of chloroplasts in the leaves. Explain why apple trees with apple scab fungus produce smaller apples than
- June 2025, Biology Paper 1 Foundation, Q06.1 (1 mark): One symptom of chickenpox is small blisters on the skin. Suggest one way chickenpox spreads from an infected person to other people. [1 mark]
- June 2025, Biology Paper 1 Foundation, Q06.2 (1 mark): Chickenpox is caused by a type of pathogen that cannot be treated with antibiotics. Give the reason why chickenpox cannot be treated with antibiotics. [1 mark]
- June 2025, Biology Paper 1 Foundation, Q06.3 (1 mark): What does a vaccine contain that causes a person to become immune to a disease? [1 mark]
- June 2025, Biology Paper 1 Foundation, Q06.4 (3 marks): Give three reasons why a new vaccine must be tested. [3 marks] 1 2 3
- June 2025, Biology Paper 1 Foundation, Q06.5 (6 marks): Explain how a vaccine for chickenpox gives immunity against the disease. You should refer to how the body responds to: • the vaccine • chickenpox pathogens that
- June 2024, Biology Paper 1 Higher, Q03.1 (1 mark): What type of microorganism causes measles? [1 mark]
- June 2024, Biology Paper 1 Higher, Q03.2 (2 marks): Suggest two ways the spread of measles can be reduced. Do not refer to vaccination in your answer. [2 marks] 1 2
- June 2024, Biology Paper 1 Higher, Q03.3 (4 marks): Describe how the measles vaccine helps a person to become immune to the measles pathogen. [4 marks]
- June 2024, Biology Paper 1 Higher, Q03.4 (2 marks): Explain how viruses cause illness. [2 marks]
- June 2024, Biology Paper 1 Higher, Q03.5 (3 marks): Drugs can help to reduce the symptoms of the norovirus infection. New drugs must go through clinical trials before being licensed for use. Give three reasons wh
- June 2024, Biology Paper 1 Foundation, Q04.1 (1 mark): Which is a symptom of gonorrhoea? [1 mark] Tick () one box. Damaged immune system Pain when urinating Reduced body temperature Table 2 shows the number of repo
- June 2024, Biology Paper 1 Foundation, Q04.2 (1 mark): The number of cases of gonorrhoea in each city might not be accurate. Suggest one reason why. [1 mark]
- June 2024, Biology Paper 1 Foundation, Q04.3 (1 mark): Which is the best way to present the data from Table 2? [1 mark] Tick () one box. Bar chart Line graph Scatter diagram
- June 2024, Biology Paper 1 Foundation, Q04.4 (1 mark): The data is given as per 100 000 of the population and not as the total number of people with gonorrhoea. Suggest why. [1 mark]
- June 2023, Biology Paper 1 Higher, Q01.7 (2 marks): Measles is a communicable disease. A virus causes measles. Describe how the measles virus is transferred from person to person. [2 marks]
- June 2023, Biology Paper 1 Higher, Q01.8 (2 marks): Scientists estimate that 17% of the UK population have athlete’s foot. The estimated UK population is 67 961 900 Calculate how many people are estimated to have
- June 2023, Biology Paper 1 Higher, Q01.9 (1 mark): Athlete’s foot fungus grows in moist conditions. Suggest one way a person could reduce their chance of catching athlete’s foot. [1 mark]
- June 2023, Biology Paper 1 Higher, Q07.2 (2 marks): The scientist concluded: ‘S. aureus is resistant to antibiotics C and E’. Explain the evidence for this conclusion. Use Figure 9. [2 marks]
- June 2023, Biology Paper 1 Higher, Q07.3 (2 marks): The scientist later discovered that S. aureus is not resistant to antibiotic E. Suggest how the method was developed and showed that S. aureus is not resistant
- June 2023, Biology Paper 1 Higher, Q07.4 (1 mark): What was the independent variable in this investigation? [1 mark] Tick () one box. The ratio of area of infection : total tissue area The treatment injected ar
- June 2023, Biology Paper 1 Higher, Q07.7 (1 mark): What is the range of results for the treatment with stem cells only? [1 mark] From to
- June 2023, Biology Paper 1 Higher, Q07.8 (4 marks): A student looked at the results and concluded: ‘Injections of stem cells containing antibiotic should be used to treat all implant-related infections’. Evaluate
- June 2023, Biology Paper 1 Foundation, Q06.7 (2 marks): Measles is a communicable disease. A virus causes measles. Describe how the measles virus is transferred from person to person. [2 marks]
- June 2023, Biology Paper 1 Foundation, Q06.8 (2 marks): Scientists estimate that 17% of the UK population have athlete’s foot. The estimated UK population is 67 961 900 Calculate how many people are estimated to have
- June 2023, Biology Paper 1 Foundation, Q06.9 (1 mark): Athlete’s foot fungus grows in moist conditions. Suggest one way a person could reduce their chance of catching athlete’s foot. [1 mark]
- June 2022, Biology Paper 1 Higher, Q01.2 (1 mark): Salmonella food poisoning is caused by bacteria in food. Give one symptom of salmonella food poisoning. Do not refer to vomiting or diarrhoea in your answer. [1
- June 2022, Biology Paper 1 Higher, Q01.3 (1 mark): What is the name of the first antibiotic developed? [1 mark] A child with a severe bacterial infection was given a course of antibiotics. Figure 1 shows how the
- June 2022, Biology Paper 1 Higher, Q01.4 (1 mark): The concentration of live bacteria in the body continued to increase after starting the course of antibiotics. Suggest one reason why. [1 mark]
- June 2022, Biology Paper 1 Higher, Q01.5 (1 mark): After 3 days of taking the antibiotic: • the child felt better • there were still bacteria in the child’s body. Why did the child feel better? [1 mark] Tick ()
- June 2022, Biology Paper 1 Higher, Q01.6 (1 mark): Suggest why doctors do not give antibiotics to patients with minor infections. [1 mark]
- June 2022, Biology Paper 1 Higher, Q01.7 (1 mark): A vaccine will stimulate the production of antibodies. Which part of the blood in Figure 2 produces antibodies? [1 mark] Tick () one box. A B C D
- June 2022, Biology Paper 1 Foundation, Q03.1 (1 mark): What type of pathogen causes rose black spot disease? [1 mark] Tick () one box. Bacterium Fungus Protist Virus
- June 2022, Biology Paper 1 Foundation, Q03.3 (2 marks): Explain why plants with yellow leaves grow slowly. [2 marks]
- June 2022, Biology Paper 1 Foundation, Q03.4 (2 marks): The spread of rose black spot can be controlled using different methods. Draw one line from each method of control to the explanation of how it works. [2 marks]
- June 2022, Biology Paper 1 Foundation, Q03.5 (1 mark): Tobacco plants may become infected with a pathogen called TMV. What type of pathogen is TMV? [1 mark] Tick () one box. Bacterium Fungus Protist Virus Malaria i
- June 2022, Biology Paper 1 Foundation, Q03.6 (1 mark): How is the malaria pathogen transferred to humans? [1 mark]
- June 2022, Biology Paper 1 Foundation, Q03.7 (1 mark): How can the spread of malaria pathogens be reduced? [1 mark] Tick () one box. Avoid sexual contact Cook food thoroughly Drain water from swamps Use a tissue wh
- June 2022, Biology Paper 1 Foundation, Q05.2 (1 mark): Salmonella food poisoning is caused by bacteria in food. Give one symptom of salmonella food poisoning. Do not refer to vomiting or diarrhoea in your answer. [1
- June 2022, Biology Paper 1 Foundation, Q05.3 (1 mark): What is the name of the first antibiotic developed? [1 mark]
- June 2022, Biology Paper 1 Foundation, Q05.4 (1 mark): The concentration of live bacteria in the body continued to increase after starting the course of antibiotics. Suggest one reason why. [1 mark]
- June 2022, Biology Paper 1 Foundation, Q05.5 (1 mark): After 3 days of taking the antibiotic: • the child felt better • there were still bacteria in the child’s body. Why did the child feel better? [1 mark] Tick ()
- June 2022, Biology Paper 1 Foundation, Q05.6 (1 mark): Suggest why doctors do not give antibiotics to patients with minor infections. [1 mark]
- June 2022, Biology Paper 1 Foundation, Q05.7 (1 mark): A vaccine will stimulate the production of antibodies. Which part of the blood in Figure 8 produces antibodies? [1 mark] Tick () one box. A B C D
- November 2021, Biology Paper 1 Higher, Q04.1 (3 marks): Draw one line from each disease to the pathogen that causes the disease. [3 marks] Disease Pathogen Gonorrhoea Malaria Measles Bacterium Fungus Protist Virus
- November 2021, Biology Paper 1 Higher, Q04.2 (2 marks): Malaria is transmitted by mosquitos. Male mosquitos can be sterilised so they are infertile. The spread of malaria is reduced by releasing sterile mosquitos int
- November 2021, Biology Paper 1 Higher, Q04.3 (1 mark): Name the piece of equipment used to view the virus. [1 mark]
- November 2021, Biology Paper 1 Higher, Q04.4 (3 marks): How many times longer is the fungal spore than the virus? Use Figure 4. [3 marks] Number of times longer =
- November 2021, Biology Paper 1 Higher, Q04.5 (3 marks): Explain why plants infected with tobacco mosaic virus grow slowly. [3 marks]
- November 2021, Biology Paper 1 Foundation, Q02.1 (1 mark): Which substance is used as an antibiotic? [1 mark] Tick () one box. Aspirin Digitalis Penicillin Gonorrhoea and chlamydia are two sexually transmitted infectio
- November 2021, Biology Paper 1 Foundation, Q02.2 (1 mark): Give one symptom of gonorrhoea. [1 mark]
- November 2021, Biology Paper 1 Foundation, Q02.3 (2 marks): Give two control variables used in this investigation. [2 marks] 1 2 Figure 2 shows the results.
- November 2021, Biology Paper 1 Foundation, Q02.4 (1 mark): Which antibiotic did not kill either type of bacterium? [1 mark] Tick () one box. A B C D
- November 2021, Biology Paper 1 Foundation, Q02.5 (1 mark): Which antibiotic would be the most effective to treat a person with a gonorrhoea infection? [1 mark] Tick () one box. A B C D
- November 2021, Biology Paper 1 Foundation, Q02.6 (1 mark): Which antibiotic would be the most effective to treat a person who had both gonorrhoea and chlamydia infections? [1 mark] Tick () one box. A B C D
- November 2021, Biology Paper 1 Foundation, Q02.7 (1 mark): Antibiotics cannot be used to treat HIV infections. Suggest one reason why. [1 mark]
- November 2021, Biology Paper 1 Foundation, Q02.8 (1 mark): Some people go to nail salons to have their nails shaped and painted. Suggest one way workers in nail salons can reduce the risk of infections being spread. [1
- November 2021, Biology Paper 1 Foundation, Q02.9 (1 mark): Suggest one reason why fungal infection of toenails is more common than fungal infection of fingernails. [1 mark]
- November 2021, Biology Paper 2 Higher, Q01.7 (6 marks): A new contraceptive drug for men is being tested. The drug: • is given in one injection • stops sperm being able to fertilise eggs • is effective for up to 13 y
- November 2021, Biology Paper 2 Foundation, Q06.7 (6 marks): A new contraceptive drug for men is being tested. The drug: • is given in one injection • stops sperm being able to fertilise eggs • is effective for up to 13 y
- November 2020, Biology Paper 1 Higher, Q04.2 (4 marks): Gonorrhoea is a bacterial disease. A new vaccine is being developed against gonorrhoea. Describe how a vaccine would work to prevent gonorrhoea. [4 marks]
- November 2020, Biology Paper 1 Higher, Q04.3 (2 marks): Explain how vaccinating chickens reduces the number of cases of salmonella food poisoning. [2 marks]
- November 2020, Biology Paper 1 Higher, Q04.4 (1 mark): Give one way that the spread of salmonella food poisoning from one human to another is controlled. Do not refer to vaccination in your answer. [1 mark]
- November 2020, Biology Paper 1 Higher, Q04.5 (1 mark): The number of cases of salmonella food poisoning is usually higher in summer than in winter. Suggest one reason why. [1 mark]
- November 2020, Biology Paper 1 Higher, Q06.1 (1 mark): How much more time did the clinical trials take compared with the preclinical testing? [1 mark] Tick () one box. 3 years 3.5 years 5 years 6.5 years
- November 2020, Biology Paper 1 Higher, Q06.2 (1 mark): Suggest one reason why low doses of the drug are used in Phase 1 clinical trials. [1 mark]
- November 2020, Biology Paper 1 Higher, Q06.3 (2 marks): Suggest two reasons why healthy volunteers are used in Phase 1 clinical trials. [2 marks] 1 2
- November 2020, Biology Paper 1 Higher, Q06.4 (1 mark): The results of clinical trials can only be published after peer review by other scientists. Suggest one reason why the results must be reviewed by other scienti
- November 2020, Biology Paper 1 Higher, Q06.5 (6 marks): A drug is only licensed for the medical conditions it was tested to treat in the clinical trials. Drug regulations: • control what drugs a doctor can prescribe
- November 2020, Biology Paper 1 Foundation, Q02.1 (1 mark): Preclinical testing is done in a laboratory. What is the drug tested on in a laboratory? Give one example. [1 mark]
- November 2020, Biology Paper 1 Foundation, Q02.2 (1 mark): How many years did the clinical trials take for the drug in Figure 2? [1 mark] Time for clinical trials = years
- November 2020, Biology Paper 1 Foundation, Q02.3 (1 mark): During Phase 1 clinical trials, the drug is tested on healthy volunteers using low doses. What is the main purpose of Phase 1 testing? [1 mark] Tick () one box
- November 2020, Biology Paper 1 Foundation, Q02.4 (1 mark): What is a placebo? [1 mark]
- November 2020, Biology Paper 1 Foundation, Q02.5 (1 mark): Who knows which patients are given the placebo and which patients are given the drug in a double blind trial? [1 mark] Tick () one box. Not the patients or the
- November 2020, Biology Paper 1 Foundation, Q02.6 (2 marks): Give two control variables in this investigation. [2 marks] 1 2
- November 2020, Biology Paper 1 Foundation, Q02.7 (1 mark): None of the children was given a placebo. Suggest one reason why. [1 mark] Figure 3 shows the results. Figure 3
- November 2020, Biology Paper 1 Foundation, Q02.8 (1 mark): What was the mean body temperature after 6 hours for the children given ibuprofen? [1 mark] Mean body temperature = °C
- November 2020, Biology Paper 1 Foundation, Q02.9 (2 marks): The doctors concluded that children with a high body temperature should be given ibuprofen and not paracetamol. Give two reasons for the doctors’ conclusion. Us
- November 2020, Biology Paper 1 Foundation, Q04.1 (2 marks): Draw one line from each disease to the type of pathogen that causes the disease. [2 marks] Disease Type of pathogen Gonorrhoea Measles Bacterium Fungus Protist
- November 2020, Biology Paper 1 Foundation, Q04.2 (2 marks): Give two ways that the body prevents pathogens entering the body. [2 marks] 1 2
- November 2020, Biology Paper 1 Foundation, Q04.3 (6 marks): If pathogens do enter the body the immune system tries to destroy the pathogens. Describe how the immune system defends the body against disease. [6 marks]
- November 2020, Biology Paper 1 Foundation, Q04.4 (1 mark): Give one reason why antibiotics cannot be used to treat HIV infections. [1 mark]
- November 2020, Biology Paper 1 Foundation, Q04.5 (2 marks): Give two ways to prevent the spread of HIV. [2 marks] 1 2
- November 2020, Biology Paper 1 Foundation, Q04.6 (1 mark): Some people with a HIV infection develop AIDS. Some people with AIDS may die from a different type of infection, such as a chest infection. Why do people with A
- June 2019, Biology Paper 1 Higher, Q01.3 (1 mark): Digitalis is a drug that slows the heart rate. Where does the drug digitalis originate from? [1 mark] Tick () one box. Bacteria Foxgloves Mould Willow Beta blo
- June 2019, Biology Paper 1 Higher, Q04.1 (1 mark): What type of pathogen causes malaria? [1 mark] Tick () one box. Bacterium Fungus Protist Virus
- June 2019, Biology Paper 1 Higher, Q04.2 (4 marks): Give two methods used to prevent people catching malaria. Give a reason why each method works. [4 marks] Method 1 Reason Method 2 Reason
- June 2019, Biology Paper 1 Higher, Q04.5 (4 marks): Give one reason for what is happening to the number of bacteria at each of the stages. [4 marks] Stage A Stage B Stage C Stage D
- June 2018, Biology Paper 1 Higher, Q02.1 (2 marks): Explain what a non-communicable disease is. [2 marks]
- June 2018, Biology Paper 1 Higher, Q05.1 (1 mark): Suggest one reason why the actual number of cases of measles in England and Wales might be higher than is shown in Table 3 [1 mark]
- June 2018, Biology Paper 1 Higher, Q05.2 (2 marks): Calculate the percentage decrease in the number of medically confirmed cases of measles between 2012 and 2015 [2 marks] Percentage decrease = %
- June 2018, Biology Paper 1 Higher, Q05.3 (2 marks): One reason for the decrease in the number of cases of measles is that more children were vaccinated against the disease. Vaccinating a large proportion of the p
- June 2018, Biology Paper 1 Higher, Q05.4 (6 marks): Figure 8 shows the concentration of measles antibodies in the blood of a boy. Figure 8 Explain the differences between antibody production after the vaccine inj
- June 2018, Biology Paper 2 Higher, Q02 (6 marks): Pseudomonas bacteria cause infections in hospital patients. A new strain of Pseudomonas bacteria has evolved. This new strain can only be killed by one antibiot
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